Save the Ovaries - Surgical Management of Simple Ovarian Cysts in Children and Adolescents
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Laparoscopic ovarian cyst surgery.
- Who it may be relevant to
- Registry conditions: Ovarian Cyst Benign. Basic parameters: 1 year — 18 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Switzerland
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The purpose of this study is to evaluate which operative technique should be used for managing simple ovarian cysts in girls and adolescents. The two techniques that are being compared are laparoscopic cyst enucleation and laparoscopic cyst deroofing. The investigators will assess the effect of both techniques on the ovarian reserve and the risk of cyst recurrence.
Interventions
- Procedure Laparoscopic ovarian cyst surgery
Laparoscopic ovarian cyst surgery is any surgery with the goal of removal or drainage of an ovarian cyst. The exact surgical technique will be predefined by randomization.
Primary outcome measures
- Postoperative change of AMH level [Time frame: 8 weeks]
Secondary outcome measures (1)
- Postoperative recurrence rate [Time frame: 14 weeks]
Eligibility criteria
Inclusion criteria
- Symptomatic simple cysts ≥ 4 cm with indication for surgical intervention
- Asymptomatic cysts ≥ 4 cm, with surgical indication due to persistence or increase in size
- Asymptomatic cysts ≥ 4 cm with other pathology as surgical indication, if known preoperatively
- Age 12 months - 18 years
- Parents/legal custodian and patient give consent, for patients unable to consent due to their health condition or developmental status they show no signs of unwillingness to participate
- Symptomatic simple cysts ≥ 4 cm with indication for surgical intervention on both ovaries (each ovary will count as one)
Exclusion criteria
- Neonatal ovarian cysts (age <12 months)
- Age >18 years
- Complex cysts (with solid components, e.g., Teratoma, risk or suspicion of malignancy)
- Paratubar/paraovarian cysts
- Medical reason that precludes cyst enucleation (e.g. severe coagulopathy)
- Neither signed informed consent form or inadequate german, french or english language skills to give informed consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Switzerland · 2 centers
- University Children's Hospital Basel — Basel
- University Children's Hospital Zurich — Zurich
Identifiers
NCT: NCT06852313 · SAVEOVPRO2025