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Recruiting NCT06719258

Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation

Observational Humidifier Lung Mechanical Fragility Respiratory Complication

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: MR850, FP950.
Who it may be relevant to
Registry conditions: Humidifier Lung, Mechanical Fragility, Respiratory Complication. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Canada
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation: Benefit of the F & P950 Heated Humidifier: Comparison With the MR 850 on Clinical Events of Under-humidification

Overview

When mechanical ventilation is initiated, a humidification method should be chosen. There is two methods: heat and humidity exchanger filters or heated humidity. The second method is recognized to be more efficient, but many external factors can influence its performance. Insufficient humidity results in observable problems, such as difficult management of respiratory secretions. The study compare two heated humidifiers already used in ICU. Data will be collected retrospectively from June 1, 2021.

Interventions

  • Device MR850
    This humidifier will be used straight away for patients whose intubation is expected to last longer than 24 hours.
  • Device FP950
    This humidifier will be used straight away for patients whose intubation is expected to last longer than 24 hours.

Primary outcome measures

  • Endotracheal tube occlusion requiring emergency tube change [Time frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)]
  • Bronchoscopy [Time frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)]
  • Tracheal saline instillations [Time frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)]
  • Thick secretions [Time frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)]
  • Change humidifier settings [Time frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)]
Secondary outcome measures (1)
  • Other elements that may be influenced by the quality of the humidification used during mechanical ventilation [Time frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)]

Eligibility criteria

Inclusion criteria

  • ≥ 18 years old
  • Admitted to intensive care
  • Under invasive mechanical ventilation with the usual indications for the use of a heated humidifier (prolonged invasive mechanical ventilation and / or protective ventilation requiring high respiratory rates.

Exclusion criteria

  • Mechanical venitilation immediately after surgery (<24h)
  • Imminent extubation or planned intubation of very short duration (<24h)
  • Enrolled in the SAVE-ICU study in the group receiving volatile agents with the AnaConDa system.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

Canada · 1 center
  • Institut Universitaire de Cardiologie et de Pneumologie de Québec — Québec

Identifiers

NCT: NCT06719258 · 2022-3714

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗