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Not yet recruiting NCT06714201

CUrrent Practices of Intensive Care for the Management of Acute Respiratory Distress Syndrome in EurOpe.

— Observational ARDS (Acute Respiratory Distress Syndrome)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: ARDS (Acute Respiratory Distress Syndrome). Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

This study seeks to gain a comprehensive understanding of current ARDS management practices across European ICUs, with a particular focus on the use of LTV and PP therapy, which have been shown to improve outcomes in ARDS patients. The primary objectives focus on evaluating how LTV and PP are implemented across different institutions, while secondary objectives encompass a broader assessment of other ARDS treatment strategies. These include mechanical ventilation approaches, including PEEP titration, the use of NMBAs, and advanced extra-corporal therapies like ECMO and extracorporeal carbon dioxide removal (ECCO2R). Additionally, the study will explore diagnostic methods and decision-making processes that guide ARDS management in diverse clinical settings.

Detailed description

This is a cross-sectional survey designed to collect data on the current practices of ARDS management in ICUs across Europe. The survey will be administered electronically, allowing for the efficient collection of responses from a broad and diverse group of healthcare professionals.

Primary outcome measures

  • Proportion of ICUs utilising prone positioning for ARDS patients. [Time frame: Survey period (December 2024 - March 2025)]
  • PaO2/FiO2 threshold for starting prone positioning. [Time frame: Survey period (December 2024 - March 2025)]
  • Distribution of the extent of prone positioning used in participating ICUs. [Time frame: Survey period (December 2024 - March 2025).]
  • Mean duration per prone positioning cycles. [Time frame: Survey period (December 2024 - March 2025)]
  • Mean minimum number of prone position cycles. [Time frame: Survey period (December 2024 - March 2025)]
  • Commonly reported criteria for ending prone positioning therapy. [Time frame: Survey period (December 2024 - March 2025)]
  • Proportion of ICUs adhering to tidal volume restrictions [Time frame: Survey period (December 2024 - March 2025)]
  • Mean tidal volumes used for mild, moderate, and severe ARDS. [Time frame: Survey period (December 2024 - March 2025)]
Secondary outcome measures (6)
  • Proportion of ICUs using volume-controlled vs pressure-controlled ventilation. [Time frame: Survey period (December 2024 - March 2025)]
  • Types of PEEP titration methods and recruitment manoeuvres. [Time frame: Survey period (December 2024 - March 2025)]
  • Proportion of ICUs using NMBAs for ARDS patients. [Time frame: Survey period (December 2024 - March 2025).]
  • Frequency of corticosteroid and nitric oxide use. [Time frame: Survey period (December 2024 - March 2025)]
  • Proportion of ICUs with ECMO/ECCO2R availability and implementation. [Time frame: Survey period (December 2024 - March 2025).]
  • Variation in prone position extent by country. [Time frame: Survey period (December 2024 - March 2025).]

Eligibility criteria

Inclusion criteria

  • Healthcare professionals (physicians and nurses) who are currently employed in an ICU that treats ARDS patients and are actively involved in their management.

Exclusion criteria

  • There are no specific exclusion criteria for this study, as the aim is to gather as broad a range of perspectives and practices as possible from ICUs treating ARDS patients.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Other

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT06714201 · UKE-KIM-MH-001

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗