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Not yet recruiting NCT06684678

Individualized Automatic Coaching Message for Glycemic Management and Depressive Symptom

No phase Interventional Diabetes Mellitus, Type 1 Continuous Glucose Measurement

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: individualized automatic coaching message for glycemic management and depressive symptom.
Who it may be relevant to
Registry conditions: Diabetes Mellitus, Type 1, Continuous Glucose Measurement. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
South Korea
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Efficacy of Individualized Automatic Coaching Message Based on the Metrics of Continuous Glucose Monitoring and Depressive Symptom: A Randomized Controlled Trial

Overview

This is a single-center, randomized, prospective, confirmatory study of efficacy of individualized automatic coaching message for glycemic management and depressive symptom in patients with type 1 diabetes. The study will enroll patients with type 1 diabetes who are applying continuous glucose monitoring (CGM) and receiving twice-monthly non-face-to-face management by a dedicated education nurse through the Type 1 Diabetes Home Care Project and Educational Consultation program. For 12 weeks, the intervention group will receive weekly personalized coaching messages for glycemic management based on data from continuous glucose monitoring and bi-weekly personalized coaching messages for depression symptoms based on depression questionnaires, instead of non-face-to-face diabetes management. The control group will continue their current treatment and non-face-to-face diabetes management. The aim of this study is to evaluate whether the efficacy of automated, personalized coaching messages for glycemic management and depressive symptoms is non-inferior to the current non-face-to-face management approach in people with type 1 diabetes.

Interventions

  • Other individualized automatic coaching message for glycemic management and depressive symptom
    For 12 weeks, the intervention group will receive weekly personalized coaching messages for glycemic management based on data from continuous glucose monitoring and bi-weekly personalized coaching messages for depression symptoms based on depression questionnaires, instead of non-face-to-face diabetes management.

Primary outcome measures

  • Time In Range [Time frame: Week 12]
Secondary outcome measures (8)
  • Diabetes treatment satisfaction [Time frame: Week 12]
  • Depressive symptoms [Time frame: Week 12]
  • Time In Tight Range [Time frame: Week 12]
  • Level of Glycated Hemoglobin [Time frame: Week 12]
  • Time Above Range [Time frame: Week 12]
  • Time Below Range [Time frame: Week 12]
  • Coefficient of Variation [Time frame: Week 12]
  • Glycemic Management Indicator [Time frame: Week 12]

Eligibility criteria

Inclusion criteria

  • Patients with type 1 diabetes, age 18-75 years old
  • Patients who have used continuous glucose monitoring at least three months and have enrolled in Type 1 Diabetes Home Care Project and Educational Consultation program.
  • Patients with at least 70% of 14 days of continuous glucose monitor data within the past month
  • Glycated hemoglobin 7% or higher, or Glycated hemoglobin 6% or higher but less than 7% and failing to meet 1 of the continuous glucose monitor blood glucose target values: time in range (70-180 mg/L) 70% or less, or time below range (<70 mg/L) 4% or more, or time above range (>180 mg/L) 25% or more, or glucose management indicator (GMI) 7% or more, or coefficient of variation (CV%) 36% or more.
  • Currently receiving treatment with multiple insulin injection therapy
  • Patients who have access to KakaoTalk via smartphone and are able to communicate with it
  • Voluntarily agreed to participate in this clinical study.

Exclusion criteria

  • Steroid and immunosuppressant users. But it can be included if patients continuously maintain same drug dose at least three months.
  • Breastfeeding or pregnant patients
  • Patients who do not voluntarily consent to the study
  • Anyone deemed unsuitable by the investigator to participate in the study

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Supportive care

Study locations

South Korea · 1 center
  • Samsung Medical Center — Seoul

Identifiers

NCT: NCT06684678 · SamsungMC_ENDO_2 · SMO124027 · 2024F-2 · RS-2024-00399025

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗