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Recruiting NCT06684028

PET Image Exploration of Novel Tracer [68Ga]-FAPI-JNU Imaging Studies in Patients with Malignant Tumors

No phase Interventional Cancer Solid Malignancies

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: 68Ga-FAPI-JNU.
Who it may be relevant to
Registry conditions: Cancer, Solid Malignancies. Basic parameters: 18 years — 85 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

To investigate the biological distribution of a new tracer 68Ga-FAPI-JNU in the primary, metastatic and normal tissues of patients with malignant tumors, and to evaluate the biological distribution of 68GA-FAPI-JNU with standardized uptake values.

Detailed description

PET/CT imaging was performed about 1 hour after the patient was injected with the novel tracer 68Ga-FAPI-JNU. SUVmax and SUVmean values of the area of interest were mapped by two diagnostic physicians with more than 5 years of experience after the imaging was completed.

Interventions

  • Drug 68Ga-FAPI-JNU
    Patients will receive the novel tracer 68Ga-FAPI-JNU dose of approximately 2-5 mCi per person

Primary outcome measures

  • Evaluation of the distribution of 68Ga-FAPI-JNU in tumors, metastases and normal tissues [Time frame: 4 hour]

Eligibility criteria

Inclusion criteria

  • The subjects sign the informed consent voluntarily and can complete the test according to the protocol requirements;
  • Age 18-85 years old, male or female;
  • Clinically diagnosed as malignant tumor, diagnostic criteria refer to biopsy or other imaging such as CT and MRI;
  • ECOG score is 0-3 points;

Exclusion criteria

  • Patients with a history or allergic constitution to any component of the developer, including alcohol;
  • pregnant or lactating women;
  • Patients with mental illness or related history;
  • Patients who cannot or cannot undergo a PET/CT scan;

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Diagnostic

Study locations

China · 1 center
  • Affiated Hospital of Jiangnan University — Wuxi

Identifiers

NCT: NCT06684028 · LS2024013

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗