Recruiting NCT06601829
Congenital Hepatic Fibrosis and Autosomal Recessive Polycystic Kidney Disease in Children at Sohag University Hospital
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: abdominal ultrasound.
- Who it may be relevant to
- Registry conditions: Congenital Hepatic Fibrosis and Autosomal Recessive Polycystic Kidney Disease in Children at Sohag University Hospital. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
polycystic kidney disease is aherditary disorder characterized by the formation of numerous fluid filled cysts in the kidneys which can lead to progressive renal impairment PKDencompasses aspectrum of disorders with autosomal dominant polycystic kidneydisease and autosomal recessive polycystic kidney disease being the two main types
Interventions
- Other abdominal ultrasound
abdominal ulterasound showing multiple cysts in the kidnets and hepatic fibrosis
Primary outcome measures
- incidence of congenital hepatic fibrosis in patient with autosomal recessive polycyctic kidney disease [Time frame: 12 months]
Eligibility criteria
Inclusion criteria
- pediatric patients aged 0-18 years both male and female patients
Exclusion criteria
- patients whose guardians dont provide informed consent patients who are not complient with follow up vists and data collection protocols
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-crossover
Study locations
Egypt · 1 center
- Sohag university Hospital — Sohag
Publications
- Paul BM, Vanden Heuvel GB. Kidney: polycystic kidney disease. Wiley Interdiscip Rev Dev Biol. 2014 Nov-Dec;3(6):465-87. doi: 10.1002/wdev.152. Epub 2014 Sep 3. PMID 25186187
- Salman MA, Elgebaly A, Soliman NA. Epidemiology and outcomes of pediatric autosomal recessive polycystic kidney disease in the Middle East and North Africa. Pediatr Nephrol. 2024 Sep;39(9):2569-2578. doi: 10.1007/s00467-024-06281-0. Epub 2024 Jan 23. PMID 38261064
- Khare A, Krishnappa V, Kumar D, Raina R. Neonatal renal cystic diseases. J Matern Fetal Neonatal Med. 2018 Nov;31(21):2923-2929. doi: 10.1080/14767058.2017.1358263. Epub 2017 Aug 2. PMID 28764564
- Webster AC, Nagler EV, Morton RL, Masson P. Chronic Kidney Disease. Lancet. 2017 Mar 25;389(10075):1238-1252. doi: 10.1016/S0140-6736(16)32064-5. Epub 2016 Nov 23. PMID 27887750
- Lucchetti L, Chinali M, Emma F, Massella L. Autosomal dominant and autosomal recessive polycystic kidney disease: hypertension and secondary cardiovascular effect in children. Front Mol Biosci. 2023 Mar 10;10:1112727. doi: 10.3389/fmolb.2023.1112727. eCollection 2023. PMID 37006611
Identifiers
NCT: NCT06601829 · soh-Med-24-08-01MS