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Recruiting NCT06593184

Efficacy of Trans-spinal Magnetic Stimulation on Functional Mobility in Chronic Stroke Patients

No phase Interventional Stroke Sequelae Gait Disorders, Neurologic Stroke

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Trans-spinal magnetic stimulation, Sham Comparator.
Who it may be relevant to
Registry conditions: Stroke Sequelae, Gait Disorders, Neurologic, Stroke. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Brazil
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The goal of this clinical trial is to learn if trans-spinal magnetic stimulation works to treat gait disorders in chronic stroke adults. It will also learn about the safety of trans-spinal magnetic stimulation. The main questions it aims to answer are: Does trans-spinal magnetic stimulation enhance chronic stroke participants gait and functional mobility? Does the technique cause any side effects? Researchers will compare trans-spinal magnetic stimulation to a sham (a look-alike stimulation with no real effect) to see if trans-spinal magnetic stimulation works to treat gait disorders and improve functional mobility. Participants will: Receive trans-spinal magnetic stimulation with treadmill training or a sham stimulation with treadmill training every day for 2 weeks.

Interventions

  • Device Trans-spinal magnetic stimulation
    Trans-spinal magnetic stimulation activates afferent spinal roots and increases cortical excitability.
  • Device Sham Comparator
    Sham trans-spinal magnetic stimulation involves masking, where the sound of stimulation persists even though no magnetic pulses are delivered

Primary outcome measures

  • Functional Mobility [Time frame: Enrollment (Day 0); End of treatment (2 weeks); Follow-up after 30 days post-treatment]
Secondary outcome measures (6)
  • Independency level [Time frame: Enrollment (Day 0); End of treatment (2 weeks); Follow-up after 30 days post-treatment]
  • Lower limb motor function [Time frame: Enrollment (Day 0); End of treatment (2 weeks); Follow-up after 30 days post-treatment]
  • Balance [Time frame: Enrollment (Day 0); End of treatment (2 weeks); Follow-up after 30 days post-treatment]
  • Perceived change in treatment [Time frame: End of treatment (2 weeks)]
  • Spasticity [Time frame: Enrollment (Day 0); End of treatment (2 weeks); Follow-up after 30 days post-treatment]
  • Sensory Function [Time frame: Enrollment (Day 0); End of treatment (2 weeks); Follow-up after 30 days post-treatment]

Eligibility criteria

Inclusion criteria

  • Confirmation of Stroke by digital or physical imaging or medical report
  • Gait impairment
  • Stroke with at least 6 months after ictus

Exclusion criteria

  • Metallic implants in spinal cord
  • Major orthopedic/rheumatological disorders
  • Incapacity of verbal or non-verbal communication

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Triple blind
Primary purpose
Treatment

Study locations

Brazil · 3 centers
  • Federal University of Paraiba — João Pessoa
  • Federal University of Pernambuco — Recife
  • Federal University of Rio de Janeiro — Rio de Janeiro

Identifiers

NCT: NCT06593184 · tsMS_Stroke_Gait

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗