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Recruiting NCT06566950

BFR Training on Muscle Morphology

No phase Interventional Blood Flow Restriction Training Eccentric Training Muscle Morphology Patellofemoral Pain Syndrome

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Low load-BFRt, Sham Low load-BFRt, High load-Eccentric training.
Who it may be relevant to
Registry conditions: Blood Flow Restriction Training, Eccentric Training, Muscle Morphology, Patellofemoral Pain Syndrome. Basic parameters: 15 years — 35 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Indonesia
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Effectiveness of Blood Flow Restriction Training on Muscle Morphology and Prevention of Patellofemoral Pain Syndrome and Anterior Cruciate Ligament Injury

Overview

This randomized clinical trial study compares high-load eccentric training (HL-Et), sham LL-BFRt, and low-load blood flow restriction (LL-BFRt) in sportsmen. The primary inquiries it seeks to address are: Is LL-BFR superior to HL-Et and sham LL-BFRt in terms of improving muscle morphology? Is LL-BFR a more effective Patellofemoral Pain Syndrome and ACL injury preventive than HL-Et and sham LL-BFRt? The three intervention groups that will be randomly assigned to participants are LL-BFRt, sham LL-BFRt, and HL-Et. Participants are expected to carry out: Participants in LL-BFRt will be required to perform LL eccentric training at 30% of their repetition maximum (RM) and 70% of their artery occlusion pressure (AOP). This training will include stairs, single leg squat, and single leg deadlift. Participants in HL-Et will be required to perform LL eccentric training at 70% of their maximum number of repetitions (RM). In order to determine whether muscular morphology and the prevention of Patellofemoral Pain Syndrome and ACL injury improve following the interventions and follow-up, researchers will compare LL-BFRt, sham LL-BFRt, and HL-Et.

Interventions

  • Procedure Low load-BFRt
    The participants' two legs will be subjected to 70% arterial occlusion pressure when the physical therapist applies the BFR cuffs. After that, participants will be required to complete eccentric exercises with a maximum repetition count of 30%, such as stairs, single leg squat, and single leg deadlift.
  • Procedure Sham Low load-BFRt
    The participants' two legs will be subjected to 10% arterial occlusion pressure when the physical therapist applies the BFR cuffs. After that, participants will be required to complete eccentric exercises with a maximum repetition count of 30%, such as stairs, single leg squat, and single leg deadlift.
  • Procedure High load-Eccentric training
    The physical therapist will instruct the participants to complete eccentric exercises at a maximum of 70% repetitions, such as stairs, single leg squat, and single leg deadlift.

Primary outcome measures

  • Muscle cross-sectional area [Time frame: 8 weeks]
  • Vastus medial obliques fiber angle [Time frame: 8 weeks]
  • Patella position [Time frame: 8 weeks]
Secondary outcome measures (2)
  • Incidence of patellofemoral pain syndrome [Time frame: 1 year]
  • Incidence of anterior cruciate ligament injury [Time frame: 1 year]

Eligibility criteria

Inclusion criteria

  • Being between the ages of 15 and 35
  • Play level 1 sports (fight martial arts, basketball, futsal, and soccer) at least twice a week
  • Never experienced an Patellofemoral Pain Syndrome or ACL injury before
  • Never experienced a grade III sprain or strain
  • Consent to participate in the study until its conclusion and provide informed consent.

Exclusion criteria

  • Having a tumor, cancer, vena thromboembolic disease, obesity, diabetes, hypertension, anemia, and renal failure
  • Disabilities or those who are disabled.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Indonesia · 1 center
  • Physical therapy laboratory, College of Medicine, Universitas Udayana and ROM Physiotherap — Denpasar

Identifiers

NCT: NCT06566950 · 1791/UN14.2.2.VII.14/LT.2024

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗