NON-COlorectal Liver METastases Undergoing Liver Resection
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: liver resection.
- Who it may be relevant to
- Registry conditions: Liver Metastases. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Electronic Dataset of NON-COlorectal Liver METastases Undergoing Liver Resection
Overview
Liver metastases (LM) are common in various types of malignant diseases, either at the diagnosis of the primary tumour or at a later time point. While the resection of colorectal LM (CRLM) is a well-established procedure, with survival rates superior to chemotherapy alone, controversial data still exist on liver resection for non-colorectal LM (NCRLM) (2, 3). These patients comprise a diverse and heterogeneous group usually excluded from surgery due to advanced tumour stage or the presence of concomitant extrahepatic disease. To date, no randomized clinical trial on the surgical treatment of NCRLM has been conducted, and only few retrospective reports are available.The scope of this research project is to develop a large registry of patients undergoing liver surgery for non-colorectal liver metastases.
Interventions
- Procedure liver resection
Resection of non-colorectal liver metastases
Primary outcome measures
- Overall Survival [Time frame: From date of enrollment until the date of death from any cause assessed up to 36 months]
Secondary outcome measures (1)
- Disease-free Survival [Time frame: From date of enrollement until the date of first documented progression assessed up to 36 months]
Eligibility criteria
Inclusion criteria
- Signature informed consent
- Age ≥ 18 years
- Histologically confirmed diagnosis of NCRLM (first diagnosis or relapse)
- Liver resection performed.
Exclusion criteria
- ASA IV
- Severe psychiatric pathology
- Unable to follow a clinical examination pattern during observation.
- Patient submitted exclusively to interventional locoregional procedures other than liver resection.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06542926 · NONCOLMET01