Recruiting NCT06531460
Nutritional Therapy Enriched With Omega-3 in Patients With Lung Resection
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Fish oil enteral supplementation, Fish oil oral supplementation, Enteral nutrition without fish oil, Oral nutritional supplement without fish oil.
- Who it may be relevant to
- Registry conditions: Lung Cancer, Surgery. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Mexico
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effect of Perioperative Nutrition Enriched With Omega-3 on the Incidence of Infections in Oncologic Patients Following Lung Resection
Overview
The aim of this study is to analyze the effect of enriched formula with omega-3 in the 30-day incidence infection and inflammatory response following lung resection surgery in lung cancer patients.
Interventions
- Dietary supplement Fish oil enteral supplementation
Omega-3 (4.2 g), administered through an enteral feeding tube, three days before surgery - Dietary supplement Fish oil oral supplementation
Omega-3 (4.2 g), orally administered enriched nutritional formula, drinking at home three days before surgery - Dietary supplement Enteral nutrition without fish oil
Enteral formula without omega-3 administered through an enteral feeding tube, three days before surgery - Dietary supplement Oral nutritional supplement without fish oil
Oral nutritional supplement without omega-3 orally administered, drinking at home three days before surgery
Primary outcome measures
- 30-day incidence infection [Time frame: 30-day incidence infection following lung resection in lung cancer patients.]
Secondary outcome measures (5)
- Changes in prostaglandin E2 [Time frame: At the beginning of nutritional therapy and at day-4 following surgery]
- Changes in Interleukin-6 [Time frame: At the beginning of nutritional therapy and at day-4 following surgery]
- Changes in Tumor Necrosis Factor Alpha (TNF-α) [Time frame: At the beginning of nutritional therapy and at day-4 following surgery]
- Number of participants with therapeutic antibiotics prescription [Time frame: During the hospital stay until 30-day]
- Hospital lenght of stay [Time frame: During the hospital stay until 90-day]
Eligibility criteria
Inclusion criteria
- Lung cancer diagnosis
- Elective surgery for lung resection schedule at least four days before surgery
- Signed informed consent.
Exclusion criteria
- Acute or chronic organ failure as hepatic or renal insufficiency
- Patients with fish-allergy
- History of any surgery within 3 months
- Immunocompromised patients
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Prevention
Study locations
Mexico · 1 center
- National Institute of Respiratory Diseases — Mexico City
Identifiers
NCT: NCT06531460 · C34-24