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Recruiting NCT06506565

Low-Dose Ketamine Infusion During Burn Wound Care

Phase IV Interventional Burn Pain Dissociation Opioid

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Ketamine, 0.9% NaCl.
Who it may be relevant to
Registry conditions: Burn, Pain, Dissociation, Opioid. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

A Randomized, Placebo-Controlled, Double-Blind Evaluation of Low-Dose Ketamine Infusion During Burn Wound Care Procedures to Improve Pain Intensity and Reduce Opioid Consumption

Overview

The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.

Interventions

  • Drug Ketamine
    Infusion during wound care
  • Drug 0.9% NaCl
    Infusion during wound care

Primary outcome measures

  • Analgesia [Time frame: up to 7 days from enrollment]

Eligibility criteria

Inclusion criteria

  • Admitted to burn service with thermal injury

Exclusion criteria

  • unable/unwilling to consent within 72 hours
  • unable to report NRS
  • known contraindication to ketamine
  • < than 18 years of age
  • pregnant
  • incarcerated
  • TBSA over 50 %

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Quadruple blind
Primary purpose
Treatment

Study locations

United States · 1 center
  • Regional One Health — Memphis

Identifiers

NCT: NCT06506565 · 23-09751-FB

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗