A Clinical Study for Developing Artificial Intelligence(AI)-Based Clustering Model for Personalized Medicine in Acute Respiratory Failure
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Acute Respiratory Failure. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- South Korea
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
A Clinical Study for Developing AI-based Clustering Model for Personalized Medicine in Acute Respiratory Failure: Single Center, Prospective Cohort Study
Overview
The investigators will prospectively collect clinical information to develop a clustering analysis model and confirm phenotype for patients with acute respiratory failure who admit to the intensive care unit and require oxygen supply beyond a high flow nasal cannula, and a control group without acute respiratory failure. and clinical characteristics and prognosis will be compared.
Primary outcome measures
- Hospital Mortality [Time frame: From date of admission until the date of hospital discharge or date of death from any cause, whichever came first, assessed up to 1 year]
Secondary outcome measures (3)
- ICU Mortality [Time frame: From date of ICU admission until the date of ICU discharge or date of death from any cause, whichever came first, assessed up to 6 months]
- Hospital length of stay [Time frame: From date of hospital admission until the date of hospital discharge, assessed up to 1 years]
- ICU length of stay [Time frame: From date of ICU admission until the date of ICU discharge, assessed up to 6 months]
Eligibility criteria
\# Inclusion Criteria:
\- Acute Respiratory Failure group
Among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital, if all of the following conditions are met:
1\) Age 18 or older 2) Patients who require treatment with high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) due to acute respiratory failure.
\- control group For comparative analysis, among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital who meet all of the following conditions, they are registered as a control group with the consent of the subjects and undergo the same research procedure.
- Age 18 or older
- Patients who do not require high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) treatment
- Exclusion Criteria:
If any of the following criteria applies, participants will not be permitted to participate in this clinical trial.
- Patients 48 hours after oxygen treatment (HFNC, NIV (BIPAP or CPAP), MV)
- Patients transferred from another hospital
- Patients with limitations in treatment
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
South Korea · 1 center
- Samsung Medical Center — Seoul
Identifiers
NCT: NCT06479421 · 2023-08-003