Severe Lung Disease in Childhood
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: lung function measurements.
- Who it may be relevant to
- Registry conditions: Lung Disease Chronic. Basic parameters: 1 Day — 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Denmark
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Long Term Outcome of Severe Lung Disease in Childhood
Overview
Only little information exists about the long term consequences of having severe lung disease in childhood. The patient population is heterogenous and the prognostic markers are few. This observational study will investigate which parameters that can be used to predict the outcome of having severe lung disease in childhood.
Detailed description
All patients aged 0-18 years at the HCA Childrens Hospital with a severe lung disease will prospectively be registered in a database.
At a yearly follow up, data from the patient record will be registered. Informed consent from the patients and/or their parents will be obtained. Registered data will include height, weight, results of lung function tests and imaging diagnostics.
The study will provide knowledge of the prognosis of different lung diseases and how to monitor lung function in children.
Interventions
- Diagnostic test lung function measurements
Patients will once a year be monitored with different lung function methods
Primary outcome measures
- FEV1 [Time frame: 18 years]
- FVC [Time frame: 18 years]
- Lung Clearance Index (LCI) [Time frame: 18 years]
Secondary outcome measures (1)
- height [Time frame: 18 years]
Eligibility criteria
Inclusion Criteria: severe lung disease -
Exclusion Criteria: no informed consent
\-
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Denmark · 1 center
- Hans Christian Andersen Children's Hospital — Odense
Identifiers
NCT: NCT06455800 · HCA-Lung