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Not yet recruiting NCT06452459

Glymphatic MRI Study

Observational Sleep Deprivation

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: No interventinon.
Who it may be relevant to
Registry conditions: Sleep Deprivation. Basic parameters: 18 years — 89 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Evaluation of Glymphatic Function With MRI

Overview

This study aims at identifying neuroimaging markers of glymphatic function in humans.

Interventions

  • Other No interventinon
    No intervention is anticipated. This is an observational study.

Primary outcome measures

  • Contrast enhancement [Time frame: 2 weeks]

Eligibility criteria

Inclusion criteria

  • Ability to undergo MRI without anesthesia
  • Calculated GFR greater or equal to 60 mL/min/1.73 m2

Exclusion criteria

  • Inability to obtain consent
  • Subject is incarcerated, pregnant, or lactating or suspects they may be pregnant
  • Known allergic or hypersensitivity reactions to gadolinium
  • Three or more drug allergies from separate drug classes
  • Recent or expected beed for imaging with iodinated contrast
  • Contraindications to MRI: claustrophobia, weight greater than maximum MRI scanner capacity, presence of metallic foreign body, or implanted devices not documented as MRI safe
  • History of neurosurgical procedure or cervical surgery
  • Current use of anticoagulation medications
  • Contraindication to lumbar puncture (creatinine or INR elevated above laboratory standard cutoffs)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT06452459 · IT Gadolinium Study

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗