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Recruiting NCT06354959

Prehab for Lung and Esophageal Cancer

No phase Interventional Neoplasm of Lung Neoplasms Exercise Surgery

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Prehabilitation.
Who it may be relevant to
Registry conditions: Neoplasm of Lung, Neoplasms, Exercise, Surgery. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Canada
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Prehab for Lung and Esophageal Cancer: Optimizing Well-being for Better Outcomes

Overview

Research indicates that individuals diagnosed with lung or esophageal cancer who enter treatment with higher functional capacities, improved body composition, and better nutrition status tend to experience better outcomes and a higher quality of life. The primary objective of a prehabilitation health coaching program is to enhance the overall health and well-being of patients before they undergo major surgery.This personalized 8-week program encompasses elements such as nutrition, smoking cessation, sleep hygiene, and movement, equipping participants with the knowledge and tools needed to adopt healthier lifestyles.

Detailed description

The purpose of this study is to explore the implementation, feasibility and effectiveness of a community-based prehabilitation health coaching program, including nutrition, smoking cessation, sleep hygiene and movement for individuals scheduled to undergo surgery for lung or esophageal cancer.. Participants will have the option to engage in a one-on-one prehabilitation health coaching program tailored to their needs, led by a Qualified Exercise Professional (QEP). The personalized prehabilitation plan will encompass 4-6 in-person or virtual meetings before surgery, including a structured movement plan, education on smoking cessation, sleep quality, stress reduction, mindfulness, and nutrition. Post-surgery, the QEP will provide support through counselling and scheduled sessions for a month after surgery and include one session while the patient is in hospital.

This research adopts a repeated measure, mixed-methods approach. Participants will undergo three clinical assessments at different stages: baseline, pre-surgery, and 4-6 weeks post-surgery. The findings from this study will guide future grant applications aimed at funding larger studies and the implementation of prehabilitation as part of standard of care in lung and esophageal cancer patients in Nova Scotia.

Central to the research endeavor is the driving question: "How can a community-based prehabilitation program be successfully implemented in the community, and can it lead to improved functional outcomes in patients undergoing surgery for lung or esophageal cancer?" This overarching question provides the study with its core focus and serves as a guiding force throughout the research process.

Interventions

  • Behavioral Prehabilitation
    8-week community based prehab program

Primary outcome measures

  • Feasibility- Recruitment [Time frame: 2 years]
  • Feasibility- Participant fidelity [Time frame: 2 years]
  • Feasibility - Safety [Time frame: 2 years]
  • Feasibility - Retention/Attrition [Time frame: 2 years]
  • Feasibility - Participant Experience [Time frame: 2 years]
  • Feasibility- Attendance [Time frame: 2 years]
Secondary outcome measures (7)
  • Functional Assessment of Cancer Therapy - Lung OR Esophageal (FACT-L/ FACT- E) [Time frame: 8-10 week change]
  • Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-F) [Time frame: 8-10 week change]
  • 5x chair stand [Time frame: 8-10 week change]
  • Stair climb test [Time frame: 8-10 week change]
  • Grip strength [Time frame: 8-10 week change]
  • Resting Heart rate [Time frame: 8-10 week change]
  • Resting blood pressure [Time frame: 8-10 week change]

Eligibility criteria

Inclusion criteria

  • Diagnosed with lung or esophageal cancer
  • Scheduled to receive surgical intervention in minimum 2-weeks
  • Surgeon approval
  • Able to read and write in English
  • >18 years of age

Exclusion criteria

  • Not able to provide informed consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Supportive care

Study locations

Canada · 1 center
  • Victoria General Hospital — Halifax

Publications

  • Langley JE, Sibley D, Chiekwe J, Keats MR, Snow S, Purcell J, Sollows S, Hill L, Watton D, Gaudry AE, Hashish I, Wallace A. Prehabilitation Program for Lung and Esophageal Cancers (Boosting Recovery and Activity Through Early Wellness): Protocol for a Nonrandomized Trial. JMIR Res Protoc. 2025 Mar 10;14:e60791. doi: 10.2196/60791. PMID 40063931

Identifiers

NCT: NCT06354959 · 1030020

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗