Risk Factors for AKI in Patients Undergoing VATS for Pulmonary Resection
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Duration of Surgery, Volume of Fluid in Surgery, Blood Loss.
- Who it may be relevant to
- Registry conditions: Acute Kidney Injury, Surgery, Lung Cancer. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Risk Factors for Acute Kidney Injury in Patients Undergoing Video-Assisted Thoracoscopic Surgery for Pulmonary Resection: A Prospective Observational Study
Overview
This study aims to investigate the potential factors contributing to the development of Acute Kidney Injury (AKI) in patients undergoing pulmonary resection with Video Assisted Thoracoscopic Surgery (VATS) for lung malignancy. The study will focus on demographic data, laboratory parameters, perioperative fluid management, and haemodynamics. The research will be conducted at SBÜ Ankara Atatürk Sanatorium Training and Research Hospital. The study will involve patients who have given informed consent and will undergo VATS with standard anaesthesia monitoring. Anaesthesia management will follow our routine protocol in our clinic. Patients will be divided into two groups based on whether they have a more than 25% decrease in estimated glomerular filtration rate (t-GFH) and/or a 1.5-fold increase in serum creatinine and/or a 6-hour urine volume of less than 0.5 ml/kg/h. The patients will be divided into two groups based on this definition, and the risk factors between these groups will be analysed. The preoperative routine blood values, demographic data (age, gender, height, weight, and BMI), ASA physical status, smoking and alcohol habits, comorbidities, and regular medication use will be recorded. Intraoperative urine output and haemodynamic parameters will also be monitored. Routine blood gas analysis, blood urea nitrogen (BUN), glomerular filtration rate (GFR), albumin, haemoglobin, sodium, potassium, chlorine, and magnesium will be measured and recorded, along with urine output and t-GFH. Patients will be evaluated in the hospital on the day the surgeon calls for a postoperative check-up and on the 30th postoperative day to see if there are any complications.
Interventions
- Other Duration of Surgery
Total surgery time in minutes - Other Volume of Fluid in Surgery
Fluid volume given during surgery in ml - Other Blood Loss
Blood loss during surgery in ml
Primary outcome measures
- Glomerular Filtration Rate [Time frame: 1 day]
- Serum Creatinine [Time frame: 1 day]
- Amount of Urine [Time frame: 1 day]
Eligibility criteria
Inclusion criteria
- Over 18 years of age, under 65 years of age,
- American Society of Anesthesiologists (ASA) physical status 1-3,
- Data of patients who will undergo wedge resection, segmentectomy or lobectomy with elective VATS due to lung malignancy will be examined prospectively.
Exclusion criteria
- Patients with a body mass index (BMI) less than 18.5kg/m2 or greater than 35 kg/m2,
- Those with impaired renal function (the upper limit of the creatinine reference range is more than 50%; 1.3 mg/dL for men and 1.1 mg/dL for women),
- A radiological examination was performed using radiocontrast material in the preoperative period,
- Clinically and radiologically diagnosed with congestive heart failure and treatment has been started,
- Having a history of pulmonary edema,
- Those who have used steroids and non-steroidal anti-inflammatory drugs for a long time (exceeding 30 days),
- Intubated to intensive care unit,
- In need of massive peroperative blood transfusion,
- Patients with deficiencies in the parameters examined will be excluded from the study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
Turkey (Türkiye) · 1 center
- Ankara Atatürk Sanatorium Training and Research Hospital — Ankara
Identifiers
NCT: NCT06341933 · 2024-BÇEK/41