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Recruiting NCT06291597

Vaping Adverse Lung and Heart Events Cohort

— Observational Vaping Electronic Cigarette Use

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Vaping.
Who it may be relevant to
Registry conditions: Vaping, Electronic Cigarette Use. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Canada
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

VapALERT: A Prospective, Exploratory and Adaptive Cohort Study to Identify Symptomatic and Asymptomatic Pulmonary and Cardiovascular Effects of Vaping

Overview

This prospective study assesses the pulmonary and cardiovascular effets of vaping in adult electronic cigarette users with biannual visits and a 5-year follow-up.

Detailed description

Daily vaping device users will be recruited in the Quebec City metropolitan area. Subjects will be asked to perform pulmonary function tests (spirometry, oscillometry, plethysmography, methacholine provocation) every 6 months for a 5-year follow up. Subjects will also answer a questionnaire assessing their vaping, tobacco and cannabis smoking habits, as well as their perceived respiratory symptoms. Blood draws and sputum inductions will be performed for cell counts and to measure inflammation markers.

Interventions

  • Other Vaping
    Participants use their vaping products at their own discretion and their intake is monitored via questionnaires.

Primary outcome measures

  • Number of participants who vape daily with impaired lung volumes. [Time frame: Every 6 months for 5 years]
  • Number of participants who vape daily with impaired lung diffusion capacity. [Time frame: Every 6 months for 5 years]
  • Number of participants who vape daily with impaired spirometry. [Time frame: Every 6 months for 5 years]
  • Number of participants who vape daily with airway hyperresponsiveness. [Time frame: Every 6 months for 5 years]
  • Number of participants who vape daily with changes in blood cell count. [Time frame: Every 6 months for 5 years]
  • Number of participants who vape daily with changes in sputum cell count. [Time frame: Every 6 months for 5 years]
  • Vaping, tobacco and cannabis smoking habits of participants. [Time frame: Every 3 months for 5 years]

Eligibility criteria

Inclusion criteria

  • Age 18 years or older
  • Daily electronic cigarette user
  • No respiratory infection in the 4 weeks before a visit

Exclusion criteria

  • Women who are pregnant or breast-feeding.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

Canada · 1 center
  • IUCPQ-UL — Québec

Identifiers

NCT: NCT06291597 · 22071

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗