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Recruiting NCT06213090

Patterns of Neurodevelopmental Disorders

Observational Neurodevelopmental Disorders Autism Spectrum Disorder Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection Pediatric Acute-Onset Neuropsychiatric Syndrome

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Neurodevelopmental Disorders, Autism Spectrum Disorder, Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection, Pediatric Acute-Onset Neuropsychiatric Syndrome. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Patterns of Disease, Outcomes and Treatment Response in Children With Neurodevelopmental Disorders

Overview

The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.

Detailed description

Although neurodevelopmental disorders are very prevalent (for example Autism affects 1 out of every 36 children and dyslexia affects up to 15% of the population), the etiology of such disorders is not known. The purpose of this investigation is to identify common etiologies of neurodevelopmental disorders (i.e., speech delay, global developmental delay, autism) and determine if it is possible to find early indicators of the diagnosis and foster the potential for a better prognosis of these disorders. At this time the investigators examine patients with neurodevelopment disorders with various medical investigations, but the results of these investigations are not systematically evaluated. One of the goals of this research is to systematically examine this information in order to identify patterns of test abnormalities that have not been previously described. Another goal of this research is to identify the common etiologies typically identified by the medical evaluation, so we can further refine our approach. In addition, the investigators now have the ability to evaluate biological samples for biomarkers that have potential to be diagnostically useful.

Primary outcome measures

  • Number of Patients with Specific Medical abnormalities [Time frame: up to 7 years]
Secondary outcome measures (2)
  • The number of children with abnormal clinical lab [Time frame: up to 7 years]
  • The number of children who respond to specific treatments [Time frame: up to 7 years]

Eligibility criteria

Inclusion criteria

Neurodevelopmental delays Clinical visit at an Rossignol Medical Center

Exclusion criteria

\-

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-control

Study locations

United States · 1 center
  • Rossignol Medical Center — Phoenix

Identifiers

NCT: NCT06213090 · NeuroClinical

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗