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Recruiting NCT06211907

Small Macular Holes Treated With Air

No phase Interventional Macular Holes

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Postoperative intraocular tamponade.
Who it may be relevant to
Registry conditions: Macular Holes. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Greece, Norway, Spain
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Small Macular Holes Treated With Air: A Prospective Randomized Controlled Multicenter Trial

Overview

Non-inferiority trial comparing intraocular air and gas tamponade for closure of macular holes.

Interventions

  • Device Postoperative intraocular tamponade
    Flushing the eye cavity with a tamponade at the end of surgery

Primary outcome measures

  • Macular hole closure after single surgery [Time frame: 4 weeks]
Secondary outcome measures (2)
  • Change in outcome of patient well-being [Time frame: 4 weeks and 4 months]
  • Change in visual acuity i ETDRS lines [Time frame: 4 weeks and 4 months]

Eligibility criteria

Inclusion criteria

  • Primary MH ≤250 μm
  • MH duration ≤12 months
  • No previous vitreoretinal surgery in study eye
  • Ability to sign informed consent
  • Signed informed consent
  • Age ˃18 years

Exclusion criteria

  • Previous vitreoretinal surgery in study eye
  • Secondary MH caused by other conditions than vitreomacular traction
  • Myopic MH, i.e., excessive myopia (more than -6 dioptres)
  • Traumatic MH
  • MH secondary to retinal detachment or other retinal diseases
  • Previously participation in this study

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Norway · 5 centers
  • Stavanger University Hospital — Stavanger
  • University Hospital of Northern Norway — Tromsø
  • St. Olavs University Hospital — Trondheim
  • Haukeland University Hospital — Bergen
  • Oslo University Hospital — Oslo
Greece · 1 center
  • Department of Ophthalmology, University of Thessaly — Thessaly
Spain · 1 center
  • Clinical Universitary Hospital of Santiago — Santiago de Compostela

Identifiers

NCT: NCT06211907 · REK 580226

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗