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Recruiting NCT06087692

Efficacy of Video-Based Interactive Game Therapy in Interstitial Lung Patients

No phase Interventional Interstitial Lung Disease

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Exercise.
Who it may be relevant to
Registry conditions: Interstitial Lung Disease. Basic parameters: 40 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

Interstitial lung disease (ILD) is a heterogeneous group of diseases consisting of variable amounts of inflammation and fibrosis and a wide variety of acute and chronic pulmonary disorders affecting both the interstitium and lung parenchyma. The use of gamification elements in order to encourage changes in health behaviors such as physical activity appears as an entertaining option by increasing extrinsic motivation in sedentary individuals or in diseases where physical activity is targeted. The aim of this study is to investigate the effectiveness of Nintendo Wii applied in addition to aerobic exercise in patients with ILD on exercise capacity and peripheral muscle strength, symptoms, activity and participation with objective methods, based on evidence.

Detailed description

Interstitial lung disease (ILD) is a heterogeneous group of diseases consisting of variable amounts of inflammation and fibrosis and a wide variety of acute and chronic pulmonary disorders affecting both the interstitium and lung parenchyma. Many forms of ILD are progressive over time, associated with severely disabling symptoms and poor quality of life, yet medical treatment options are often limited. There are no specific pulmonary rehabilitation guidelines for this patient population, and standard programs are adapted on a patient basis. However, it is seen that the participation and attendance of patients in pulmonary rehabilitation programs is low, and the benefits obtained from the programs are gradually lost after completing the intensive rehabilitation process and breaking contact with the rehabilitation team. For these reasons, the guidelines emphasize the need to implement new strategies that can overcome limitations, and it is stated that there is a need for research and development of new program models that will make evidence-based pulmonary rehabilitation more accessible for patients. The use of gamification elements in order to encourage changes in health behaviors such as physical activity appears as an entertaining option by increasing extrinsic motivation in sedentary individuals or in diseases where physical activity is targeted. The aim of this study is to investigate the effectiveness of Nintendo Wii applied in addition to aerobic exercise in patients with ILD on exercise capacity and peripheral muscle strength, symptoms, activity and participation with objective methods, based on evidence.

Hypotheses:

H0: Video-based game therapy applied in addition to aerobic exercise in patients with ILD has has no effect on exercise capacity, quality of life and physical fitness level.

H1: Video-based game therapy applied in addition to aerobic exercise in patients with ILD increases exercise capacity, quality of life and physical fitness level.

Patients in the Nintendo group will be included a medium intensity (40-60% of the maximum heart rate or 4-6 intensity according to the Modified Borg scale) aerobic exercise program with a horizontal bicycle ergometer 2 days a week for 8 weeks, lasting an average of 30 minutes, accompanied by a physiotherapist, and then they will be included in ''Wii Fit'' exercise program an average of 30 minutes. Patients in the aerobic exercise group will be included a medium intensity (%40-60 of the maximum heart rate or 4-6 intensity according to the Modified Borg Scala) aerobic exercise program with a horizontal bicycle ergometer, 2 days a week for 8 weeks, lasting an average of 30 minutes, accompanied by a physiotherapist. After eight weeks, all assessments will be repeated.

As a result of this study, the contribution of video-based interactive game therapy to exercise capacity, peripheral muscle strength, physical activity level, symptoms, activity and participation levels in patients with ILD will be determined and compared.

Interventions

  • Other Exercise
    -based game therapy applied in addition to aerobic exercise

Primary outcome measures

  • 6 minute walk test [Time frame: through study completion, an average of 1 year]
  • Incremental Shuttle Walk Test [Time frame: through study completion, an average of 1 year]
  • Endurance Shuttle Walk Test [Time frame: through study completion, an average of 1 year]
Secondary outcome measures (9)
  • Respiratory Muscle Strength [Time frame: through study completion, an average of 1 year]
  • Muscle strength [Time frame: through study completion, an average of 1 year]
  • Dyspnea [Time frame: through study completion, an average of 1 year]
  • Fatigue [Time frame: through study completion, an average of 1 year]
  • The Saint George Respiratory Questionnaire [Time frame: through study completion, an average of 1 year]
  • Daily Life Activities: [Time frame: through study completion, an average of 1 year]
  • International Physical Activity Questionnaire (Short Form) [Time frame: through study completion, an average of 1 year]
  • Leicester Cough Questionnaire [Time frame: through study completion, an average of 1 year]
  • Global rating of change (GRC) [Time frame: through study completion, an average of 1 year]

Eligibility criteria

Inclusion criteria

  • Diagnosed with ILD (Interstitial lung disease) by a chest diseases specialist, aged between 40-65 years, and have been under follow-up for at least 6 months according to the current ATS/ERS guidelines.
  • Clinically stable, with no exacerbations or infections.
  • Able to walk, with no visual or auditory impairments.
  • Patients with cognitive abilities sufficient to understand commands.

Exclusion criteria

Orthopedic and neurological problems that could hinder exercise training.

  • Changes in medical treatment during the study.
  • Unstable cardiac diseases.
  • Insufficient cooperation.
  • Diagnosed visual, auditory, vestibular, or neurological problems that could affect balance.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Factorial
Masking
Open label
Primary purpose
Treatment

Study locations

Turkey (Türkiye) · 1 center
  • İstanbul Faculty of Medicine — Istanbul

Publications

  • Holland AE, Hill CJ, Conron M, Munro P, McDonald CF. Short term improvement in exercise capacity and symptoms following exercise training in interstitial lung disease. Thorax. 2008 Jun;63(6):549-54. doi: 10.1136/thx.2007.088070. Epub 2008 Feb 1. PMID 18245143
  • Arslan MS, Ozer AY, Bingol Z, Okumus G. Effectiveness of Active Video Games as a Training Tool in Patients With Interstitial Lung Disease: A Randomised Controlled Trial. Respirology. 2026 Mar;31(3):265-275. doi: 10.1002/resp.70166. Epub 2025 Dec 4. PMID 41344887

Identifiers

NCT: NCT06087692 · PHD Thesis

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗