a Cohort Study of Ischemic Cerebrovascular Disease
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Intravenous thrombolysis.
- Who it may be relevant to
- Registry conditions: Ischaemic Stroke. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
a Prospective, Multicenter Cohort Study of Ischemic Cerebrovascular Disease
Overview
This study aims to establish a multicenter, large-scale, prospective cohort of patients with ischemic stroke. Various biological samples such as blood, feces, and urine are collected to identify biomarkers associated with ischemic stroke. By integrating demographic information, clinical indicators, imaging parameters, and biomarker parameters, the study aims to develop risk assessment, early warning, and prognosis prediction models. Additionally, the study aims to identify key genes and explore relevant signaling pathways related to ischemic stroke.
Interventions
- Other Intravenous thrombolysis
Intravenous thrombolysis with alteplase within the time window of stroke onset in stroke patients
Primary outcome measures
- Cerebrovascular events [Time frame: 3 months of onset in patients]
- mRS scores [Time frame: 3 months of onset in patients]
Eligibility criteria
Inclusion criteria
- Clinical diagnosis of ischemic stroke.
- Age ≥ 18 years.
- Signed informed consent form.
Exclusion criteria
- Patients with moderate to severe mental disorders or dementia who cannot cooperate to complete the informed consent and follow-up procedures.
- Patients with neurological functional impairment caused by conditions such as migraine aura, epilepsy, or other non-ischemic strokes.
- Agitated patients who cannot cooperate with imaging examinations.
- Pregnant or lactating patients, as well as those planning to become pregnant within 90 days.
- Patients with concurrent malignant tumors or severe systemic diseases with an expected survival period of less than 90 days.
- Patients who have participated in other clinical studies within 30 days prior to enrollment or are currently participating in other interventional clinical studies.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Xiangya Hospital, Central South University — Hunan
Identifiers
NCT: NCT05922540 · 202304068