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Recruiting NCT05914987

Determining Individualized Cancer Therapy in Pancreatic Cancer

Observational Pancreatic Neoplasms

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Targeted Therapy.
Who it may be relevant to
Registry conditions: Pancreatic Neoplasms. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Profile-Related Evidence Determining Individualized Cancer Therapy in Pancreatic Cancer (PREDICT-PANC)

Overview

This is a non-therapeutic exploratory observational precision oncology study designed to collect and analyze data that demonstrate the clinical efficacy and tolerability of personalized treatments based on molecular tumor profiling assessments (i.e., matched therapy) in adult pancreatic cancer patients. Patient medical records, obtained both retrospectively and prospectively, will be examined for results of molecular profiling obtained through standard of care testing to help understand how well molecular testing might predicts response to therapy. Patient demographic and outcome parameters to be evaluated include, but are not limited to, tumor response, time to treatment failure, patient survival, and toxicity.

Interventions

  • Other Targeted Therapy
    Approved interventions based on the subject's genomic profile will be provided to investigators for consideration for anti-tumor therapy.

Primary outcome measures

  • Number of Subjects Receiving Targeted Therapy [Time frame: 5 years]

Eligibility criteria

Inclusion criteria

  • Age ≥18 years.
  • Pathologically confirmed pancreatic cancer.
  • Ability to understand a written informed consent document and the willingness to sign it

Exclusion criteria

  • Age <18 years.
  • Primary cancer diagnosis other than pancreatic cancer.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • Froedtert Hospital and the Medical College of Wisconsin — Milwaukee

Identifiers

NCT: NCT05914987 · PRO00048019

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗