Telerehabilitation in Hemato-oncological Survivors
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Home-based training, Center-based training.
- Who it may be relevant to
- Registry conditions: Hematologic Malignancy, Lymphoma. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Czechia
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Remotely Monitored Rehabilitation in Hemato-oncological Survivors After Treatment: The Tele@Home Study
Overview
This study investigates whether the 12-week home-based exercise training with remote guidance and telemonitoring compared to regular center-based training leads to better long-term cardiorespiratory fitness and physical activity levels in post-treatment patients with lymphoma.
Detailed description
80 lymphoma cancer patients post-treatment (except adjuvant treatment) will be enrolled in the study. Cardiorespiratory fitness (peak oxygen consumption), adverse events, body composition, quality of life, costs and adherence to exercise prescription will be evaluated at baseline, 12-week, and year after enrollment.
Investigators assume that home-based training with remote guidance and telemonitoring with objective training data obtained during rehabilitation after cancer treatment will improve long-term motivation and effectiveness of independent training in cancer survivors, resulting in superior cardiorespiratory fitness and physical activity levels.
Interventions
- Device Home-based training
Patients will be instructed to perform three weekly training sessions at home (30 to 50 min/session, at an intensity of 70-85% of their maximum heart rate). Patients in the home training group complete the first three training sessions in the clinic under direct supervision. During these sessions, patients are introduced to the duration and intensity of training. The trainer will provide remote guidance (feedback on training frequency, duration, and intensity) via telephone call once a week. Dur - Device Center-based training
Patients receive three training sessions a week with 30 to 50 min duration at 70 - 90% of their maximal heart rate at the outpatient clinic under direct supervision. Exercise modalities will be walking on a treadmill, riding a bicycle ergometer, and resistance training. Physiotherapists will track the attendance rate and training adherence during the training program.
Primary outcome measures
- Cardiorespiratory fitness [Time frame: Change from baseline to 12 weeks and 52 weeks]
Secondary outcome measures (8)
- Health-related quality of life [Time frame: Change from baseline to 12 weeks and 52 weeks]
- Satisfaction - self-completed questionnaire [Time frame: 12 weeks and 52 weeks]
- Body water [Time frame: Change from baseline to 12 weeks and 52 weeks]
- Muscle mass [Time frame: Change from baseline to 12 weeks and 52 weeks]
- Body fat percentage [Time frame: Change from baseline to 12 weeks and 52 weeks]
- Incidence of exercise adverse events assessed by 5 grade scale [Time frame: Data will be recorded continuously from the intervention's baseline for 12 weeks and then for 52 weeks]
- Training adherence (Number of compliant participants) [Time frame: 12 weeks]
- Maximum Grip Strength [Time frame: Change from baseline to 12 weeks and 52 weeks]
Eligibility criteria
Inclusion Criteria: Participants
- with hemato-oncological malignancy / lymphoma (in last two months)
- after cancer systemic chemotherapy-based treatment
- with clinically stable state
- with the ability to perform a cardiopulmonary exercise test
- with the ability to understand and write in the Czech language
- with an internet connection at home
- literacy with information and communication technology
Exclusion Criteria: Participants
- with acute heart disease or decompensation in the previous six weeks,
- with psychological severe, cognitive disorders,
- serious training limitations (musculoskeletal disorders)
- currently carried out the recommendations for physical activity (150min per week)
- who take part in a training program under supervision elsewhere
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Supportive care
Study locations
Czechia · 1 center
- University Hospital Brno — Brno
Publications
- Chamradova K, Batalik L, Winnige P, Dosbaba F, Hartman M, Batalikova K, Janikova A, Nehyba S, Felsoci M, Pepera G, Su JJ. Effects of home-based exercise with telehealth guidance in lymphoma cancer survivors entering cardio-oncology rehabilitation: rationale and design of the tele@home study. Cardiooncology. 2024 Jul 30;10(1):46. doi: 10.1186/s40959-024-00249-7. PMID 39080734
Identifiers
NCT: NCT05779605 · NU23-09-00048