Effect of Sleep Disorder on the Development of Lung Tumors
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Sleep Disorder, Lung Tumor. Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effect of Sleep Disorder on the Development of Lung Tumors, a Perspective, Single-centered Study
Overview
The goal of this observational study is to observe the lung tumor development in lung tumor patients with long-term sleep disorder. The main questions it aims to answer are: * will long-term sleep disorder promote the malignancy of lung tumor * if so, how exactly will the microenvironment of lung tumor change Participants will receive PSQI scale and MRI functional brain imaging before surgery, blood and tumor tissue will be collected during the surgery. Researchers will set non-sleep disorder group as control group to see if lung tumor microenvironment change when long-term sleep disorder exists in lung tumor patiens.
Interventions
- Other
Not applicable, there is no intervention description in this study.
Primary outcome measures
- tumor microenvironment in sleep-disordered lung cancer patients [Time frame: 3 months after surgery]
Secondary outcome measures (2)
- peripheral blood levels of neurotransmitters in sleep-disordered lung cancer patients [Time frame: 3 months after surgery]
- Functional brain imaging in sleep-disordered lung cancer patients [Time frame: 3 months after surgery]
Eligibility criteria
Inclusion criteria
- 18-75 years old
- elective sublobectomy for primary lung tumor
- ASA grade I-II
- Informed consent of the patient or family
Exclusion criteria
- Combination of serious heart, liver, kidney, central nervous system, blood system, immune system diseases or serious mental illness
- Combination of other cancers
- untreated active lung infection
- patients with preoperative neoadjuvant radiotherapy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT05745506 · IIT-2022-0160