Nutriomics and Artificial Intelligence Nutrition Obesity Cohort
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Obesity. Basic parameters: from 19 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- South Korea
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The purpose of this study is to establish a prospective cohort. From registration to the 5th year, basic investigation, specific examinations for cardiovascular and metabolic disease, basic blood tests, collection of human material samples, and clinical event follow-up are conducted yearly. The obese group will be examined yearly, and telephone follow-up will be conducted if necessary. The control group will participate in the baseline survey once enrollment and clinical event follow-up by phone will be conducted annually thereafter. From the 6th year, only clinical event follow-up will be conducted.
Detailed description
The obese group will enroll 500 people within 1 year of study initiation and follow-up annually. The control group will enroll 30 patients a year for 5 years.
Primary outcome measures
- Differences of nutriomics according to obesity phenotypes [Time frame: At five years of study]
Secondary outcome measures (1)
- Clinical events [Time frame: three years, four years, five years, etc]
Eligibility criteria
Inclusion criteria for the obese group
- Adults 19 years of age or older
- Obese patients with chronic diseases such as cardiovascular disease, hypertension, diabetes, and metabolic syndrome (BMI ≥ 25 kg/m2, \[BMI ≥ 30 kg/m2, including 10% or more\])
Inclusion criteria for the control group
- Adults 19 years of age or older
- Those with BMI 18.5\~24.9 kg/m2
Exclusion criteria for the obese group
- Serious non-cardiovascular disease with life expectancy less than 6 months
- Pregnant or suspected of being pregnant or are lactating
- Patients within 3 months of organ transplantation
- Patients currently being treated for acute transplant rejection
- Patients treated for acute coronary syndrome (myocardial infarction, unstable angina) and discharged within 6 months
- Patients with acute cerebral infarction within 6 months of being hospitalized and discharged
- Type 1 Diabetes
- Patients taking steroids, female hormones
- Those who have difficulty using smartphones
Exclusion criteria for the control group
- Serious non-cardiovascular disease with life expectancy less than 6 months
- Pregnant or suspected of being pregnant or are lactating
- Persons who are continuously taking medications prescribed by a doctor due to chronic diseases excluding hypertension and dyslipidemia
- Within 5 years of diagnosis of malignant tumor
- Those who have difficulty using smartphones
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
South Korea · 1 center
- Yonsei University Health System, Severance Hospital — Seoul
Identifiers
NCT: NCT05494138 · 4-2022-0645