The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement
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An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Single-shot adductor canal block, Continuous femoral nerve block.
- Who it may be relevant to
- Registry conditions: Osteo Arthritis Knee, Gonarthrosis. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Russia
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement (AdORe - ACB)
Overview
Total knee replacement (TKR) is considered the most effective and safe method of radical treatment of late stages of knee osteoarthritis. A well-known problem of TKR is a severe postoperative pain syndrome, which is observed in more than 50% of patients. Femoral nerve block (FNB) is the "gold standard" for continuous postoperative analgesia after total knee replacement, as it is effective in reducing the frequency of use of opioid analgetics and reduce the duration of hospitalization. At the same time, the negative effect of this method is the motor blockade of the quadriceps femoris muscle which leads to functional impairment and is associated with an increased risk of falling. Adductor canal block (ACB) provides adequate analgesia comparable to femoral nerve block. Moreover, ACB doesn't affect the motor function of the quadriceps femoris muscle. The possibility of enhanced recovery after total knee replacement is the reason to compare single-shot adductor canal block and continuous femoral nerve block.
Interventions
- Procedure Single-shot adductor canal block
Postoperative analgesia in this group will be carried out by a single-shot bolus of 20 ml Ropivacaine 0.5% in the region of the middle third of the adductor canal. - Procedure Continuous femoral nerve block
Postoperative analgesia in this group will be carried out by continuous infusion of local anesthetics through a catheter installed to the femoral nerve in the area of the femoral triangle. Ropivacaine 0.2% solution will be used for postoperative analgesia. Local anesthetic infusion rate is 4 ml/h to 10 ml/h.
Primary outcome measures
- Ambulation distance [Time frame: postoperative day 1]
Secondary outcome measures (11)
- Ambulation distance [Time frame: postoperative day 2]
- Timed up and go test [Time frame: postoperative day 1]
- Timed up and go test [Time frame: postoperative day 2]
- 10 meters walk test [Time frame: postoperative day 1]
- 10 meters walk test [Time frame: postoperative day 2]
- 30 seconds chair stand test [Time frame: postoperative day 1]
- 30 seconds chair stand test [Time frame: postoperative day 2]
- 5 times sit to stand test [Time frame: postoperative day 1]
- 5 times sit to stand test [Time frame: postoperative day 2]
- time to readiness to dicharge [Time frame: 30 day]
- length of hospitalization [Time frame: 30 day]
Eligibility criteria
Inclusion criteria
- Age ≥ 18
- Planned primary total knee replacement
- Planned neuraxial anesthesia
- Written informed consent
Exclusion criteria
- Urgent surgery
- Planned revision total knee replacement
- Known allergic reaction to anesthetics
- Confirmed localized infection at the puncture sites
- Confirmed localized tumor at the puncture sites
- Peripheral neuropathy of the lower extremities
- Parkinson's disease
- Previously enrolled in this trial
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Treatment
Study locations
Russia · 1 center
- Clinical Hospital on Yauza — Moscow
Identifiers
NCT: NCT05487053 · AdORe - ACB