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Recruiting NCT05292235

Perioperative Parameter and Treatment Outcomes of Surgical Treatment for Benign Prostate Hyperplasia in Hong Kong

— Observational Benign Prostatic Hyperplasia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Benign Prostatic Hyperplasia. Basic parameters: from 18 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Hong Kong
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

A Prospective Assessment of the Perioperative Parameter and Treatment Outcomes of Surgical Treatment for Benign Prostate Hyperplasia in Hong Kong

Overview

This is a prospective data registry to assess the treatment outcomes and complications of different treatment approaches in our hospital clusters.

Detailed description

Benign prostatic hyperplasia (BPH) is a very common disease affecting men. Patients with BPH may present with voiding symptoms including hesitancy, intermittence, slow stream and sensation of incomplete emptying, and storage symptoms including urinary frequency, urgency and nocturia. Patients may also suffer from complications including urinary retention, recurrent urinary tract infection, bladder stone formation and obstructive uropathy. For patients who have lower urinary tract symptoms refractory to medications, or those who suffer from complications of BPH, transurethral prostatectomy should be considered.

Surgical intervention options have evolved from electrosurgical resection to the use of lasers for enucleation and ablation \[1\]. Aquablation and Rezum system are new minimally invasive surgical technology for BPH management. \[2,3,4\]. Different treatment approaches will result in different treatment successful rate and also potential adverse effects to patients.

However, large-scale studies investigating the different modalities of surgical treatment of BPH are lacking. Therefore, a prospective data registry is created to assess the perioperative surgical outcomes for different surgical treatment of BPH.

Primary outcome measures

  • International Prostate Symptom Score (IPSS) questionnaire total Score [Time frame: Baseline, 3 months after surgical treatment for BPH]
  • Voiding function in uroflowmetry [Time frame: Baseline, 3 months after after surgical treatment for BPH]
Secondary outcome measures (1)
  • Complication after surgical treatment [Time frame: Post operation 30 days after surgical treatment for BPH]

Eligibility criteria

Inclusion criteria

  • Patient at the age of 18 or above

Exclusion criteria

  • Patient is unable to give consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Hong Kong · 3 centers
  • Alice Ho Miu Ling Nethersole Hospital — Hong Kong
  • North District Hospital — Hong Kong
  • Prince of Wales Hospital — Shatin

Publications

  • Kahokehr A, Gilling PJ. Landmarks in BPH--from aetiology to medical and surgical management. Nat Rev Urol. 2014 Feb;11(2):118-22. doi: 10.1038/nrurol.2013.318. Epub 2014 Jan 21. PMID 24445912
  • Magistro G, Chapple CR, Elhilali M, Gilling P, McVary KT, Roehrborn CG, Stief CG, Woo HH, Gratzke C. Emerging Minimally Invasive Treatment Options for Male Lower Urinary Tract Symptoms. Eur Urol. 2017 Dec;72(6):986-997. doi: 10.1016/j.eururo.2017.07.005. Epub 2017 Jul 19. PMID 28734706
  • Faber K, de Abreu AL, Ramos P, Aljuri N, Mantri S, Gill I, Ukimura O, Desai M. Image-guided robot-assisted prostate ablation using water jet-hydrodissection: initial study of a novel technology for benign prostatic hyperplasia. J Endourol. 2015 Jan;29(1):63-9. doi: 10.1089/end.2014.0304. PMID 25000418
  • Dixon CM, Rijo Cedano E, Mynderse LA, Larson TR. Transurethral convective water vapor as a treatment for lower urinary tract symptomatology due to benign prostatic hyperplasia using the Rezum((R)) system: evaluation of acute ablative capabilities in the human prostate. Res Rep Urol. 2015 Jan 30;7:13-8. doi: 10.2147/RRU.S74040. eCollection 2015. PMID 25674555
  • Siu BWH, Leung DKW, Wong RSK, Wong CHM, Liu AQ, Yee CH, Teoh JYC, Chiu PKF, Ng CF, Lo KL. Thulium fiber laser enucleation of the prostate with SOLTIVE SuperPulsed laser systems: a prospective evaluation of early outcomes in an Asian cohort. Front Urol. 2026 Mar 30;6:1753089. doi: 10.3389/fruro.2026.1753089. eCollection 2026. PMID 41983244

Identifiers

NCT: NCT05292235 · CRE-2022.049

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗