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Recruiting NCT05008848

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Phase III Interventional Cigarette Smoking-Related Carcinoma

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Smoking Cessation Intervention, Health Promotion and Education, Informational Intervention, Questionnaire Administration.
Who it may be relevant to
Registry conditions: Cigarette Smoking-Related Carcinoma. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Cessation Interventions

Overview

This phase III trial compares the effect of text-based cessation intervention to a manual in helping rural cancer patients who smoke, quit. Text-based scheduled gradual reduction may reduce the frequency of cigarette use to zero and may be effective in quitting smoking.

Detailed description

PRIMARY OBJECTIVES:

I. To evaluate the efficacy of an eight-week text-based scheduled gradual reduction (SGR) intervention (a personalized eight-week reduction schedule paired with National Cancer Institute's \[NCI's\] Smokefree.TXT) compared to a control intervention (NCI Clearing the Air Cessation Booklet) on biochemically-validated smoking cessation six-month post-quit date in rural cancer survivors.

SECONDARY OBJECTIVE:

I. Compare the efficacy of the eight-week text-based SGR intervention and a control intervention on Linear Analog Self-Assessment (LASA)-6 overall quality of life (QOL) at 30-days post-quit date and six-months post-quit date.

OUTLINE: Patients are randomized to 1 of 2 groups.

GROUP I: Patients participate in schedule gradual reduction program over 8 weeks to reduce the frequency of cigarette use. Patients also receive cessation support messages via text messages for 12 weeks.

GROUP II: Patients receive NCI's Clearing the Air booklet to help plan to gradually quit smoking.

After completion of study, patients are followed up at 6 months.

Interventions

  • Behavioral Smoking Cessation Intervention
    Participate in schedule gradual reduction program
  • Other Health Promotion and Education
    Receive cessation support messages
  • Other Informational Intervention
    Receive NCI's Clearing the Air booklet
  • Other Questionnaire Administration
    Ancillary studies

Primary outcome measures

  • Biochemically validated tobacco cessation [Time frame: Up to 6 months post-quit date]
Secondary outcome measures (1)
  • Serially measured overall quality of life (QoL) scores obtained at baseline and at 30-days and 6-months post-quite date [Time frame: Up to 6-months post-quit date]

Eligibility criteria

Inclusion criteria

  • Have a cancer diagnosis within the past 10 years, and can currently be receiving curative treatment
  • Not currently on hospice
  • Currently smokes >= 5 cigarettes daily
  • Lives in a nonmetro/rural county (defined as having a Rural Urban Continuum Code \[RUCC\] code of 4-9)
  • Patient interested in participating in a smoking cessation program, and not currently participating in a smoking cessation clinical trial
  • Not currently using any smoking cessation pharmacotherapy (e.g. nicotine replacement therapy, bupropion or varenicline), or currently participating in any cessation program
  • Patient has a cell phone or smart phone device with texting ability
  • In order to complete the mandatory patient-completed measures, participants must be able to speak and read English
  • Age >= 18 years
  • Participant must be willing to provide a urine sample.

Exclusion criteria

  • Psychiatric illness which would prevent the patient from giving informed consent
  • Patients with impaired decision-making capacity are not eligible for this study.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Prevention

Study locations

United States · 223 centers
  • Kingman Regional Medical Center — Kingman
  • Mercy Hospital Fort Smith — Fort Smith
  • Saint Helena Hospital — St. Helena
  • Banner North Colorado Medical Center — Greeley
  • Banner North Colorado Medical Center - Loveland Campus — Loveland
  • Malcom Randall Veterans Administration Medical Center — Gainesville
  • Northeast Georgia Medical Center Braselton — Braselton
  • Northeast Georgia Medical Center-Gainesville — Gainesville
  • … and 215 more centers

Identifiers

NCT: NCT05008848 · A211901 · NCI-2021-03543 · UG1CA189823

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗