Portsmouth CORE-D Routine Care Data Repository
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Adult Hospital Patients at Risk of Adverse Outcomes. Basic parameters: from 16 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United Kingdom
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Portsmouth Clinical Outcomes REsearch Database (CORE-D)- a Research Database of Routine Electronically Recorded Patient Data to Model Adverse Clinical Outcomes and Healthcare Resource Usage
Overview
An integrated database of depersonalised routine hospital patient data consisting of demographic and disease attributes, physiological or laboratory measurements, care contacts and interventions along with associated clinical outcomes. The database is an essential resource for the development and testing of risk models and classification systems, modified as necessary for patient subgroups, which can then be introduced into clinical care to improve patient outcomes. It can also be used for large scale simulations to evaluate interventions.
Detailed description
The aims and objectives of this database of depersonalised routinely collected hospital patient data are to:
* Conduct epidemiological and observational studies of acute hospital care. * Develop and use algorithms and risk models to identify the deteriorating / sick adult so that interventions and enhanced care can be provided in a timelier manner with consequent resource and outcome improvements. This covers both the deteriorating inpatient at risk of adverse outcomes and people in the local community at risk of hospitalisation or in need of other health services. * Retrospectively evaluate interventions e.g. impact of system-wide clinical pathway introduction * Conduct simulations of clinical pathways
Primary outcome measures
- In-hospital death [Time frame: At 24 hours after an observation assessment or physiological measurement]
- In-hospital death [Time frame: 30 days after admission]
- Unanticipated ICU admission [Time frame: At 24 hours after an observation assessment or physiological measurement]
- Unanticipated ICU admission [Time frame: 30 days after admission]
- Cardiac arrest [Time frame: At 24 hours after an observation assessment or physiological measurement]
- Cardiac arrest [Time frame: 30 days after admission]
Secondary outcome measures (7)
- Diagnosis of Corona Virus Disease (COVID) infection [Time frame: 48 hours after presentation]
- Diagnosis of Corona Virus Disease (COVID) infection [Time frame: At 48 hours after an observation assessment or physiological measurement]
- Detection of Acute Organ Dysfunction [Time frame: 24 hours after presentation]
- Detection of Acute Organ Dysfunction [Time frame: 48 hours after presentation]
- Detection of Acute Organ Dysfunction [Time frame: 72 hours after presentation]
- Detection of Acute Organ Dysfunction [Time frame: 1 week after presentation]
- Detection of Acute Organ Dysfunction [Time frame: 30 days after presentation]
Eligibility criteria
Inclusion criteria
- Adult presenting at the acute hospital or receiving services from the hospital
Exclusion criteria
- Adults who have registered an opt out of research with National Health Service (NHS) Digital
- Adults who have contacted the hospital to ask that their records are not to be included in this study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
United Kingdom · 1 center
- Queen Alexandra Hospital — Portsmouth
Identifiers
NCT: NCT04983082 · PHU/2021/11