Portsmouth CORE-D Routine Care Data Repository

Официальное название

Portsmouth Clinical Outcomes REsearch Database (CORE-D)- a Research Database of Routine Electronically Recorded Patient Data to Model Adverse Clinical Outcomes and Healthcare Resource Usage

Обзор

An integrated database of depersonalised routine hospital patient data consisting of demographic and disease attributes, physiological or laboratory measurements, care contacts and interventions along with associated clinical outcomes. The database is an essential resource for the development and testing of risk models and classification systems, modified as necessary for patient subgroups, which can then be introduced into clinical care to improve patient outcomes. It can also be used for large scale simulations to evaluate interventions.

Подробное описание

The aims and objectives of this database of depersonalised routinely collected hospital patient data are to:

* Conduct epidemiological and observational studies of acute hospital care. * Develop and use algorithms and risk models to identify the deteriorating / sick adult so that interventions and enhanced care can be provided in a timelier manner with consequent resource and outcome improvements. This covers both the deteriorating inpatient at risk of adverse outcomes and people in the local community at risk of hospitalisation or in need of other health services. * Retrospectively evaluate interventions e.g. impact of system-wide clinical pathway introduction * Conduct simulations of clinical pathways

Первичные конечные точки

• In-hospital death [Срок оценки: At 24 hours after an observation assessment or physiological measurement]
• In-hospital death [Срок оценки: 30 days after admission]
• Unanticipated ICU admission [Срок оценки: At 24 hours after an observation assessment or physiological measurement]
• Unanticipated ICU admission [Срок оценки: 30 days after admission]
• Cardiac arrest [Срок оценки: At 24 hours after an observation assessment or physiological measurement]
• Cardiac arrest [Срок оценки: 30 days after admission]

Вторичные конечные точки (7)

• Diagnosis of Corona Virus Disease (COVID) infection [Срок оценки: 48 hours after presentation]
• Diagnosis of Corona Virus Disease (COVID) infection [Срок оценки: At 48 hours after an observation assessment or physiological measurement]
• Detection of Acute Organ Dysfunction [Срок оценки: 24 hours after presentation]
• Detection of Acute Organ Dysfunction [Срок оценки: 48 hours after presentation]
• Detection of Acute Organ Dysfunction [Срок оценки: 72 hours after presentation]
• Detection of Acute Organ Dysfunction [Срок оценки: 1 week after presentation]
• Detection of Acute Organ Dysfunction [Срок оценки: 30 days after presentation]

Критерии участия

Критерии включения

• Adult presenting at the acute hospital or receiving services from the hospital

Критерии исключения

• Adults who have registered an opt out of research with National Health Service (NHS) Digital
• Adults who have contacted the hospital to ask that their records are not to be included in this study

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Дизайн исследования

Модель наблюдения

Когортное

Центры проведения

Великобритания · 1 центр

• Queen Alexandra Hospital — Portsmouth

Идентификаторы

NCT: NCT04983082 · PHU/2021/11

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗