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Recruiting NCT04819542

Use of Compression Bandages in the Prevention of Post-mastectomy Lymphoceles

No phase Interventional Lymphocele

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Bandage, No bandage.
Who it may be relevant to
Registry conditions: Lymphocele. Basic parameters: from 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

Lymphocele secondary to a mastectomy whether or not associated with a lymph node procedure (sentinel lymph node or axillary dissection) is an almost systematic consequence observed in the postoperative situation in this type of surgery. This can be the source of pain, skin complications, and infection with a significant impact on the length of hospitalization for patients treated for breast cancer. There is no consensus regarding the management of lymphocele. The placement of a compression bandage after mastectomy and / or axillary dissection would allow a more efficient and rapid reduction of the lymphocele and a reduction in recurrences. This would make it possible to reduce the duration of the wearing of the drain, which determines the length of hospitalization and reduce the recurrence of lymphoceles, the punctures of which can be one of the risk factors for secondary lymphedema.

Interventions

  • Device Bandage
    Bandage
  • Device No bandage
    No bandage

Primary outcome measures

  • Proportion in percentage of patients treated successfully [Time frame: 6 months]
Secondary outcome measures (8)
  • Lymphocele volume in milliliter [Time frame: 6 months]
  • Number of lymphocele punctures [Time frame: 6 months]
  • Clinical signs associated with lymphocele [Time frame: 8 days]
  • Frequency of adverse events [Time frame: 6 months]
  • Clinical signs associated with lymphocele [Time frame: 8 days]
  • Clinical signs associated with lymphocele [Time frame: 8 days]
  • Changes in quality of life [Time frame: 6 months]
  • Changes in quality of life [Time frame: 6 months]

Eligibility criteria

Inclusion criteria

  • Patients over 18 years old,
  • Undergoing mastectomy-type surgery with or without axillary dissection for breast cancer
  • Affiliated with a health insurance plan

Exclusion criteria

  • Recurrence of breast cancer,
  • Mastectomy with RMI (immediate breast reconstruction) at the same time of operation
  • Anticoagulant treatment at curative dose
  • Arteritis obliterans of the upper limbs,
  • Other cancer during treatment,
  • Decompensated heart failure,
  • Acute infectious episode (cellulitis, erysipelas, lymphangitis)
  • Acute deep vein thrombosis upper limb ipsilateral to mastectomy,
  • Cutaneous atrophy of the upper limb,
  • Bullous dermatoses,
  • Hyperalgesia of the shoulder
  • Inability to submit to the constraints of the protocol,
  • Impossibility for the patient to achieve self-restraint at the thoracic level
  • Pregnancy,
  • Feeding with milk
  • BMI> 35
  • Adult protected by law (guardianship, curatorship and safeguard of justice).
  • Anyone who is not in a position to give their consent in writing

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

France · 1 center
  • University Hospital — Toulouse

Identifiers

NCT: NCT04819542 · RC31/17/0350

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗