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Recruiting NCT04777175

A Retrospective Study: Evaluation of the Efficacy of Immunotherapy With Rare Mutations in Non-small Cell Lung Cancer

Observational Non Small Cell Lung Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: immunity therapy.
Who it may be relevant to
Registry conditions: Non Small Cell Lung Cancer. Basic parameters: 18 years — 75 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

In advanced non-small cell lung cancer, there will be some rare mutations, such as ALK, KRAS, etc. The efficacy of these immunotherapies on these different rare mutations has not been reported. Therefore, we conducted this retrospective clinical study to explore the efficacy of immunotherapy for different rare mutations.

Interventions

  • Drug immunity therapy
    The patient receives immunotherapy

Primary outcome measures

  • PFS [Time frame: January 2021- January 2021 (1 year)]

Eligibility criteria

Inclusion criteria

  • 1.Diagnosed as advanced non-small cell lung cancer
  • 2.Confirmed as KARS, ALK, ERBB2, MET, RET, BRAF mutation

Exclusion criteria

  • The patient is diagnosed with small cell lung cancer

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 2 centers
  • Hunan Cancer Hospital — Changsha
  • Hunan Cancer hospital — Changsha

Identifiers

NCT: NCT04777175 · IRMLC

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗