Prospective Sinonasal Cancer Multi-institution Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Sinonasal Carcinoma. Basic parameters: 30 Days — 99 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Sinonasal Cancer Study to Evaluate Oncologic Outcomes and Quality of Life
Overview
This is a multi-institution prospective study of patients with sinonasal malignancies. The goal of this study is to learn more about the course of sinonasal cancer, treatment outcomes, and patient quality of life. In addition, central mutational and genomic analysis of tumor tissue will be evaluated.
Primary outcome measures
- Oncologic outcomes as measured by overall survival, disease specific survival and recurrence free survival [Time frame: Through study completion, an average of 5 years]
Secondary outcome measures (2)
- Quality of life outcomes including the University of Washington Quality of Life Questionnaire (UW-QOL v4) and the Sinonasal Outcome Test 22 (SNOT22) [Time frame: Through study completion, an average of 5 years]
- Describe the molecular foundation of sinonasal malignancies utilizing RNA sequencing to identify transcriptomic tumor profiles [Time frame: Through study completion, an average of 5 years]
Eligibility criteria
Inclusion criteria
- Subjects between the ages of 30 days (non-inclusive) and 99 years (inclusive)
- Patients with a diagnosis of sinonasal cancer
- Patients undergoing treatment at Mayo Clinic
Exclusion criteria
- Healthy individuals
- Unwilling to sign the informed consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Mayo Clinic in Rochester — Rochester
Identifiers
NCT: NCT04755855 · 20-010181