Heart Failure-USB: Prediction and Progression
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: medical chart review, data generated by direct IT export.
- Who it may be relevant to
- Registry conditions: Acute Heart Failure, Acute Coronary Syndrome, Heart Failure. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Switzerland
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical course of the disease. Data of patients who were hospitalized during the years 2010-2023 with acute coronary syndrome (ACS) and/ or with acute heart failure (AHF) will be collected and analyzed. In a subgroup cohort efficacy and safety of digoxin in patients with acute heart failure triggered by tachyarrhythmia will be evaluated.
Interventions
- Other medical chart review
data generated by medical review include Medical history, Medications at presentation, during hospitalization and at discharge, New York Heart Association (NYHA) class, Killip class, Electrocardiographic (ECG) data, echocardiographic data, Interventions (Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft (CABG), Implantable Cardioverter Defibrillator (ICD) implantation, Cardiac Resynchronization Therapy (CRT) Implantation), Outcome Information: all-cause death, HF hospitaliza - Other data generated by direct IT export
data generated by direct IT export include Anthropometric data (age, sex, height, weight), Vital signs, Laboratory data
Primary outcome measures
- number of all-cause death [Time frame: 1 to 8 years after hospitalization]
- number of HF hospitalizations [Time frame: 1 to 8 years after hospitalization]
- number of cardiovascular death [Time frame: 1 to 8 years after hospitalization]
- number of cardiovascular hospitalizations [Time frame: 1 to 8 years after hospitalization]
Eligibility criteria
Inclusion criteria
- Patients hospitalized with a primary diagnosis of ACS
- Patients hospitalized with a primary or secondary diagnosis of AHF
Exclusion criteria
- Existence of a documented statement of the patient against the scientific use of clinical data
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Switzerland · 1 center
- Cardiology, University Hospital Basel — Basel
Identifiers
NCT: NCT04000061 · 2019-00956; me19Mueller