Recruiting NCT03932279
Characterization of the Microbiome in Cutaneous T Cell Lymphoma
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cutaneous T Cell Lymphoma. Basic parameters: 18 years — 89 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Investigators plan to perform a pilot study that aims to characterize the microbiome of human cutaneous T cell lymphoma patients and compare this to the microbiome of age and sex matched controls.
Primary outcome measures
- Bacterial diversity index [Time frame: 3 months]
Eligibility criteria
Inclusion criteria
- Group 1: Patients with stage IA-IIA cutaneous T cell lymphoma
- Group 2: Patients with stage IIB and above cutaneous T cell lymphoma
- Group 3: Patients with CD30+ lymphoproliferative disorder including lymphomatoid papulosis and cutaneous anaplastic large cell lymphoma
- Group 4: Patients with plaque psoriasis with BSA>5% on routine phototherapy per standard of care
- Group 5: Patients with moderate to severe atopic dermatitis on routine bleach bath therapy per standard of care
- Group 6: Healthy individuals without the above skin conditions, similar age and sex distribution to the patients with cutaneous T cell lymphoma
- All Groups: subjects who are age 18-89 years of age at time of enrollment
- All Groups: Subjects who are able and willing to give informed consent for this study and the Dermatology Tissue Acquisition and Biorepository (STU00009443).
Exclusion criteria
- All Groups: Subjects who are younger than 18 years of age or older than 90 years of age
- All Groups: Subjects who are unable to give consent
- Patients currently on systemic antibiotics or recent (within past 4 weeks) exposure to systemic antibiotics
- We will not recruit the following populations: adults unable to consent, individuals who are not yet adults (infants, children, teenagers), pregnant women, prisoners and other vulnerable populations.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Northwestern University — Chicago
Identifiers
NCT: NCT03932279 · XZ05212018