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Recruiting NCT03770923

Effect of Some Drugs on Rheumatoid Arithritis Activity

Phase III Interventional Rheumatoid Arthritis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Rupatadine, Montelukast.
Who it may be relevant to
Registry conditions: Rheumatoid Arthritis. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Clinical Study Evaluating the Effect of Histamine 1 Receptor Antagonist and Leukotreine Receptor Antagonist on Patients With Rheumatoid Arithritis

Overview

Effect of Some Drugs on Rheumatoid Arithritis Activity.

Detailed description

The study aims at evaluating the effect of Some Drugs on Rheumatoid Arithritis Activity.

Interventions

  • Drug Rupatadine
    Rupatadine 10 mg daily
  • Drug Montelukast
    Montelukast 10 mg daily

Primary outcome measures

  • se level of IL-17 [Time frame: 6 months]

Eligibility criteria

Inclusion criteria

  • Rheumatoid arthritis

Exclusion criteria

  • liver or renal disease

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Sherief Abd-Elsalam — Tanta

Publications

  • Mostafa TM, Hegazy SK, El-Ghany SEA, Kotkata FAE. Comparative study evaluating antihistamine versus leukotriene receptor antagonist as adjuvant therapy for rheumatoid arthritis. Eur J Clin Pharmacol. 2021 Dec;77(12):1825-1834. doi: 10.1007/s00228-021-03181-2. Epub 2021 Jul 4. PMID 34218304

Identifiers

NCT: NCT03770923 · Rheumatoid Arithritis

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗