Menu
Recruiting NCT03125655

Regulation of Inflammatory Genes in Psoriasis

— Observational Psoriasis Inflammation

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Inflammatory markers.
Who it may be relevant to
Registry conditions: Psoriasis, Inflammation. Basic parameters: 19 years — 99 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.

Interventions

  • Diagnostic test Inflammatory markers

Primary outcome measures

  • Inflammatory genes [Time frame: 1 day]

Eligibility criteria

Inclusion criteria

  • Clinical diagnosis of psoriasis
  • Must be age 19 or older.
  • Must be Fitzpatrick skin type I, II, III, IV, V, VI.

Exclusion criteria

  • Subjects who do not have photosensitive disease and are not on photosensitizing medications.
  • Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy).
  • Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants.
  • Subjects who are pregnant.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-control

Study locations

United States · 1 center
  • The Kirklin Clinic — Birmingham

Identifiers

NCT: NCT03125655 · F120628003

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗