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Recruiting NCT03034187

Radiation-induced Toxicity in Prostate Cancer/ Standard-Follow-Up Program Prostate

Observational Prostate Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Prostate Cancer. Basic parameters: from 18 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Netherlands
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Radiation Induced Toxicity in Prostate Cancer

Overview

The goal is to gain insight in the development and course of the toxicity after a curative treatment of prostate cancer

Detailed description

All with curative intent treated prostate cancer patients will be enrolled in the SFP (Standard Follow-up Programme). It also includes the post -operative adjuvant treatments and the patients with positive lymph nodes.

Patients will complete weekly questionnaires to score the patient -rated toxicity. Biweekly patients are seen by the treating radiation oncologist and / or AIOS in which the physician -rated toxicity is scored. In the follow-up will always patient -rated toxicity and physician -rated toxicity can be determined.

Use of an SFP should yield a profit for the practitioner , such as the automatic generation of letters. This should apply to all SFPs .

Quality of life and toxicity in patients will be completed on the touch-screen computers at FU visits.

Primary outcome measures

  • 1. Change in Acute toxicity [Time frame: Toxicity:First visit/Wekely during RT, Acute Toxicity: 2-wekely and at the end of RT/ 2 months after RT/1, 2, 3, 4, 5 years after RT]
Secondary outcome measures (1)
  • 2. Change in patient -rated Quality-of-Life [Time frame: First visit/End of RT/ 2 months after RT/1, 2, 3, 4, 5 years after RT]

Eligibility criteria

Inclusion criteria

  • All curative treated patients with prostatecancer( with positive lymph nodes)
  • All patients who will be treated with RT( including post-operative, adjuvant treatments)
  • Are willing to fill in toxicity and QOL-questionnarys (QLQ-PR25 en de QLQ-C30)

Exclusion criteria

Patients who are not willing to fill in toxicity and QOL-questionnarys Patients who will not get RT Non-curative or palliative treated patients (with bone mestasis) Non-prostate cancer-patients

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Netherlands · 1 center
  • University Medical Center Groningen — Groningen

Identifiers

NCT: NCT03034187 · H1998-12/SFP-Prostate

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗