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Recruiting NCT02527486

Seoul National University Airway Registry

Observational Chronic Obstructive Pulmonary Disease (COPD) Asthma Asthma With Chronic Obstructive Pulmonary Disease Bronchiectasis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Chronic Obstructive Pulmonary Disease (COPD), Asthma, Asthma With Chronic Obstructive Pulmonary Disease, Bronchiectasis. Basic parameters: 20 years — 90 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
South Korea
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Airway Registry for Chronic Airway Diseases

Overview

This is a multicenter, prospective observational cohort study, in which patients with chronic airway diseases including chronic obstructive pulmonary disease(COPD), asthma, asthma-COPD overlap syndrome (ACOS) will be recruited.

Primary outcome measures

  • Death (time to death) [Time frame: upto 20 years]
Secondary outcome measures (1)
  • post-bronchodilator FEV1 change rates [Time frame: upto 20 years (at least 3 years)]

Eligibility criteria

COPD

Inclusion criteria

  • Postbronchodilator FEV1/FVC < 0.7 AND chronic respiratory symptom

Exclusion criteria

\-

Asthma

Inclusion criteria

  • Never smoker or <5PY of smoking history AND Recurrent episodes of asthma symptoms (wheezing, dyspnea, chest tightness, cough) AND (either Positive BDR OR positive metacholine/mannitol/exercise provocation test)

Exclusion criteria

\-

ACOS

Inclusion criteria

  • COPD AND Asthma (regardless of smoking status)

Exclusion criteria

\-

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

South Korea · 3 centers
  • Seoul National University Bundang Hospital — Seongnam-si
  • Seoul National University Hospital — Seoul
  • Seoul Metropolitan Government-Seoul National University Boramae Medical Center — Seoul

Publications

  • Jo YS, Park S, Kim DK, Yoo CG, Lee CH. The cutoff point of clinical chronic obstructive pulmonary disease questionnaire for more symptomatic patients. BMC Pulm Med. 2018 Feb 27;18(1):38. doi: 10.1186/s12890-018-0601-0. PMID 29482616
  • Jo YS, Lee J, Yoon HI, Kim DK, Yoo CG, Lee CH. Different prevalence and clinical characteristics of asthma-chronic obstructive pulmonary disease overlap syndrome according to accepted criteria. Ann Allergy Asthma Immunol. 2017 Jun;118(6):696-703.e1. doi: 10.1016/j.anai.2017.04.010. PMID 28583262

Identifiers

NCT: NCT02527486 · AW_registry

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗