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Recruiting NCT02087852

Kidney Cancer DNA Registry

— Observational Renal Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: salvia for germline DNA, the Kidney Cancer Questionnaire, Family History Questionnaire (when applicable), Blood draw.
Who it may be relevant to
Registry conditions: Renal Cancer. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

This registry will help us develop better methods of: * Preventing these cancers * Diagnosing these cancers * Treating these cancers

Interventions

  • Other salvia for germline DNA
  • Behavioral the Kidney Cancer Questionnaire
    Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.
  • Behavioral Family History Questionnaire (when applicable)
    Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.
  • Other Blood draw
  • Behavioral Epidemiologic Questionnaire
    Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.

Primary outcome measures

  • establish a kidney cancer registry [Time frame: 5 years]

Eligibility criteria

Inclusion criteria

Kidney Cancer Case Cohort:

  • Must be ≥ 18 years of age AND
  • Must be an English-speaker AND
  • Must have a diagnosis or suspicion of kidney cancer

Family Member Cohort:

  • Must be ≥ 18 years of age AND
  • Must be an English-speaker AND
  • Must be a blood relative of the proband. Family members of probands including mother, father, sisters, brothers, half-sisters, half-brothers, daughters, sons, grandmothers, grandfathers, as well as aunts and uncles are eligible. These individuals need not have kidney cancer, as they will be used for segregation analysis of suspected variants found in the proband; requesting DNA from relatives is required.

Control Cohort:

  • Must be ≥ 18 years of age AND
  • Must be an English-speaker AND
  • Must not have a personal history of cancer, with the exception of nonmelanoma skin cancer, AND
  • Must not be a blood relative of any cases or controls enrolled in this study

Exclusion criteria

  • Patients who, in the opinion of the primary MSKCC clinician or the investigator, have a condition that precludes their ability to provide an informed consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-control

Study locations

United States · 7 centers
  • Memorial Sloan Kettering at Basking Ridge (Consent and Follow-up) — Basking Ridge
  • Memorial Sloan Kettering Monmouth (Consent and Follow up) — Middletown
  • Memorial Sloan Kettering Bergen (Consent and Follow up ) — Montvale
  • Memorial Sloan Kettering Commack (Consent and Follow-up) — Commack
  • Memorial Sloan Kettering Westchester (Consent and Follow up) — Harrison
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) — New York
  • Memorial Sloan Kettering Nassau (Consent and Follow-Up) — Uniondale

Identifiers

NCT: NCT02087852 · 13-218

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗