Urology

2,917 trials in this section

Recruiting NCT06921733

Ultrasound Localization Microscopy in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)

— Observational Germany

Congenital Anomalies of Kidney and Urinary Tract · Lower Urinary Tract Obstruction, Congenital · Ureteropelvic Junction Obstruction

Not yet recruiting NCT07176806

The Use of Urinary Dickkopf 3 (u DKK3) as a New Biomarker Which Can Identify Patients at High Risk of Renal Allograft Dysfunction, Earlier That the Current Established Tests.

— Observational United Kingdom

Renal Transplant Failure

Recruiting NCT07172386

Preoperative Therapy of Super-selective Tumor Artery Embolization Combined With Toripalimab and Axitinib in Advanced RCC

Phase II Interventional China

Renal Cell Carcinoma (RCC)

Recruiting NCT07175480

PET/CT-Directed Free of Therapy for Metastatic RCC Patients With IMDC Favorable or Intermediate Risk

Phase II Interventional China

Renal Cell Carcinoma (RCC) · Metastatic Renal Cell Carcinoma (mRCC)

Recruiting NCT06387498

Testicular Tissue Cryopreservation (TTC)

No phase Interventional United States

Fertility Issues

Recruiting NCT04858880

Personalized Radiotherapy for Biochemical Recurrence of Prostate Cancer After Prostatectomy.

No phase Interventional Sweden

Prostate Cancer

Not yet recruiting NCT07175805

Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy

— Observational United States

Lower Urinary Tract Symptoms · Stress Urinary Incontinence · Urge Urinary Incontinence

Recruiting NCT04775355

Study to Detect Changes in Urinary and Gut Microbiome During Androgen Deprivation Therapy and Radiation Therapy in Patients With Prostate Cancer

— Observational United States

Stage I Prostate Cancer AJCC v7 · Stage II Prostate Cancer AJCC v7 · Stage IIA Prostate Cancer AJCC v7

Not yet recruiting NCT07172750

The Effect of Education on Patients' Attitudes and Anxiety Towards CAUTI Prevention

No phase Interventional Turkey (Türkiye)

Catheter Associated Urinary Tract Infection · Indwelling Urinary Catheter · Urologic Surgery

Recruiting NCT07164950

Compression Stockings to Prevent Peripheral Neuropathy Caused by Antibody-Drug Conjugates in Urothelial Carcinoma Patients

No phase Interventional China

Urothelial Carcinoma · Advanced Solid Tumors · Chemotherapy-Induced Peripheral Neuropathy

Recruiting NCT07168616

Study of PSMA PET/CT Imaging to Help Select Men With Low-Risk Prostate Cancer for Active Surveillance

— Observational Turkey (Türkiye)

Low Risk Prostate Cancer · Clinically Significant Prostate Cancer

Recruiting NCT06133543

Robot-assisted ICG-guided Sentinel Node Biopsy in Testicular Cancer

No phase Interventional Germany

Germ Cell Tumor · Seminoma · Nonseminomatous Germ Cell Tumor

Not yet recruiting NCT07172854

Pelvic Floor Muscle Training With Aerobic Exercise and Relaxation After Radical Prostatectomy

No phase Interventional —

Post Prostatectomy Incontinence · Erectile Dysfunction Following Radical Prostatectomy

Not yet recruiting NCT07172126

Clinical Trial to Evaluate the Tolerance of TQB3201 Tablets

Phase I / Phase II Interventional China

Metastatic Castration-resistant Prostate Cancer

Recruiting NCT06394570

Enfortumab Vedotin and Stereotactic Radiation for Localized, Cisplatin Ineligible Muscle Invasive Bladder Cancer

Phase I / Phase II Interventional United States

Bladder Cancer

Recruiting NCT06848868

Ambulatory Flexible URS for UTUC Surveillance

Phase I Interventional Hong Kong

Upper Tract Urothelial Carcinoma

Recruiting NCT07172685

Study on Triple Therapy Combined With HIFU for High-Tumor-Burden mHSPC

No phase Interventional China

Prostate Cancer

Not yet recruiting NCT07173517

Cost Profile and Budget Implications of Rechargeable Versus Non-rechargeable Sacral Neuromodulation Devices for Neurogenic Lower Urinary Tract Dysfunction

— Observational China

Rechargeable Sacral Neuromodulation Device · Neurogenic Lower Urinary Tract Dysfunction

Enrolling by invitation NCT03648359

Multiparametric MRI in Men With Prostate Cancer Enrolled in Active Surveillance

No phase Interventional Denmark

Prostatic Neoplasms

Recruiting NCT07025044

Assessing the Genitourinary Microbiome of Women With Overactive Bladder Undergoing Onabotulinum Toxin Type A Intradetrusor Injections

— Observational United States

Overactive Bladder (OAB) · Urge Incontinence

Enrolling by invitation NCT06958042

The Prevalence of Lower Urinary Tract Symptoms in Individuals With Chronic Obstructive Pulmonary Disease

— Observational Turkey (Türkiye)

Chronic Obstructive Pulmonary Disease (COPD)

Recruiting NCT07167329

Real-World Effectiveness and Pharmacogenetics of Belzutifan in VHL Syndrome: The BELIEVE-VHL Trial

Phase II Interventional Brazil

Von Hippel Lindau · Von Hippel Lindau Disease · Von Hippel Lindau-Deficient Clear Cell Renal Cell Carcinoma

Recruiting NCT06351904

A Study of RAG-01 in Patients With Non-muscle-invasive Bladder Cancer (NMIBC) Who Have Failed Bacillus Calmette Guérin (BCG) Therapy

Phase I Interventional Australia

Non-Muscle-Invasive Bladder Cancer (NMIBC)

Recruiting NCT03678025

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

Phase III Interventional United States, Chile +3

Castration Levels of Testosterone · Metastatic Prostatic Adenocarcinoma · Stage IV Prostate Cancer AJCC v8

Recruiting NCT06200103

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Phase II Interventional United States

Castration-Resistant Prostate Carcinoma · Stage IVB Prostate Cancer AJCC v8

Enrolling by invitation NCT05739071

JING SI HERBAL TEA and Urinary Tract Symptoms in Bladder Cancer

No phase Interventional Taiwan

Lower Urinary Tract Symptoms · Intravenous Drug Usage · Bladder Cancer

Recruiting NCT07165236

Association of POCD With Circulating Biomarkers in Patients Undergoing TUR of Bladder Tumor

— Observational Croatia

Cognitive Decline · Urinary Bladder Cancer · Frail

Enrolling by invitation NCT07164781

Effect of Use of Probiotics on Systemic Infection in Critically Ill Patients: a Double Blind, Randomized, Placebo-controlled Trial

No phase Interventional Egypt

Ventilator Acquired Pneumonia · Catheter Related Bloodstream Infection · Urinary Tract Infection

Not yet recruiting NCT07165418

A Comparison of Vorolanib Tablets Combined With Everolimus Versus Sunitinib in Patients With Advanced Renal Cell Carcinoma Who Have Progressed After Treatment With Immunotherapy Monotherapy or in Combination With TKI

Phase III Interventional China

Renal Cell Carcinoma (RCC)

Recruiting NCT07166445

Deep Learning for Automated Discrimination Between Stage T1-T2 and T3 Renal Cell Carcinoma on Contrast-Enhanced CT

— Observational China

Carcinoma, Renal Cell · Diagnostic Imaging · Pathology

Not yet recruiting NCT07163754

Use of the SiDTM v2.0 Algorithm to Assist Embiyologists in Sperm Selection During ICSI Procedures

No phase Interventional —

Male Fertility · Testicular · Sperm Parameters in Fertile and Infertile Men

Recruiting NCT06943495

Personalized vs. Fixed-Activity 177Lu-PSMA-617 Radiopharmaceutical Therapy (PRODIGY-2)

Phase I Interventional Canada

Metastatic Castrate Resistant Prostate Cancer (mCRPC)

Recruiting NCT05600400

Improving Sexual Quality of Life - Randomized Trial of Two vs Five MRI Guided SABR Treatments for Prostate Cancer

No phase Interventional Canada

Prostate Cancer · Cancer of Prostate · Prostate Adenocarcinoma

Recruiting NCT05786742

Ultra Hypofractionnated Radiotherapy With HDR Brachytherapy Boost.

No phase Interventional Canada

Prostate Cancer · Radiotherapy Side Effect · Hypofractionation

Recruiting NCT06815354

Comprehensive Assessment of Cancer Theranostic Response

No phase Interventional United States

Prostate Cancer

Recruiting NCT07162987

Prehabilitation to Patients With Prostate Cancer

No phase Interventional Denmark

Prostate Cancer (Diagnosis)

Recruiting NCT06642402

Monitoring Lupus Nephritis Through Urinary Extracellular Vesicles

— Observational Denmark

Systemic Lupus Erythematosus Nephritis

Enrolling by invitation NCT07162779

Evaluation of [68Ga]DOTA-IR-780-C-4 in PET Imaging Studies for PSMA-Positive Prostate Cancer Patients

No phase Interventional China

PET CT

Recruiting NCT04510597

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Phase III Interventional United States

Metastatic Clear Cell Renal Cell Carcinoma · Metastatic Renal Cell Carcinoma · Stage IV Renal Cell Cancer AJCC v8

Enrolling by invitation NCT07159165

Registry of MIUS for Benign Prostatic Obstruction

— Observational Turkey (Türkiye)

Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms

Recruiting NCT06834321

Clinical Study on Neoadjuvant Therapy of Homoharringtonine Combined With Androgen Deprivation for Prostate Cancer

Phase II Interventional China

Prostate CA

Recruiting NCT07126977

Video Game-Based Balance Training in Children With Lower Urinary Tract Dysfunction

No phase Interventional Turkey (Türkiye)

Lower Urinary Tract Dysfunction

Not yet recruiting NCT07159191

Envafolimab Combined With Axitinib as First-Line Treatment for Patients With Advanced Renal Cell Carcinoma

Phase II Interventional —

Advanced Renal Cell Carcinoma (aRCC)

Recruiting NCT06262516

Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

No phase Interventional United States

Urothelial Carcinoma

Not yet recruiting NCT07145034

Evaluation Of Efficacy And Safety Of Prosman™ (Prunus Domestica Extract) On Prostate Function, Serum Testosterone Levels And Quality Of Life

No phase Interventional —

Healthy

Recruiting NCT05842044

NSAID Use After Robotic Partial Nephrectomy

Phase II Interventional United States

Kidney Cancer · Renal Cancer · Renal Neoplasm

Not yet recruiting NCT07158138

A Digitally Distributed Yoga Intervention in Prostate Cancer Rehabilitation : Protocol for a Randomized Controlled Trial

No phase Interventional Sweden

Prostate Cancer Patients

Not yet recruiting NCT07055425

Association Between Qmax/eGFR Ratio and LUTS Severity in Men Over 40

— Observational —

Lower Urinary Tract Symptom · Voiding Dysfunction · Male Urological Health

Recruiting NCT05255289

Efficacy/Safety of Midurethral Sling

No phase Interventional Taiwan

Stress Urinary Incontinence

Not yet recruiting NCT07047599

Uroflowmetry and IPSS Factors Influencing Surgical Decision

— Observational —

Lower Urinary Tract Symptom · Benign Prostate Obstruction (BPO) · Voiding Dysfunction

Recruiting NCT07156903

Evaluation of Needs of Patients and Care-givers During and After Radiotherapy of Patients With Prostate Cancer

No phase Interventional Germany

Prostate Cancer Patients

Recruiting NCT07141225

Application of the "Off-Clamp And Sutureless" Technique in Robot-Assisted Partial Nephrectomy

No phase Interventional China

Renal and Urinary Disorders · Renal Cancer · Renal Particial

Not yet recruiting NCT07154914

A Novel Insight Into CRPC Progression and Immune: Evidence From Single-cell Spatial Transcriptome Multi-omics

— Observational —

Metastatic Hormone-Sensitive Prostate Cance

Recruiting NCT01492972

Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer

Phase III Interventional United States

Prostate Cancer

Not yet recruiting NCT07062133

Effectiveness of Electrical Pudendal Nerve Stimulation for Neurogenic Lower Urinary Tract Dysfunction in Pediatric Tethered Cord Syndrome Post-Surgery

No phase Interventional China

Postoperative Neurogenic Lower Urinary Tract Dysfunction Secondary to Tethered Cord Syndrome

Recruiting NCT06687421

Implementation of Precision Medicine in High-risk Prostate Cancer

— Observational Sweden

Prostate Cancer

Not yet recruiting NCT07151560

Efficacy and Safety of Two Bladder-preserving Treatment Durations With Disitamab Vedotin Plus Toripalimab Combination in Her2-expressing Muscle-invasive Bladder Cancer: A Phase II, Open-Label, Randomized Clinical Trial

Phase II Interventional —

Urology

Not yet recruiting NCT07151482

Impact of Oral Supplementation With Bioactive Collagen Peptides and Other Functional Ingredients

— Observational —

Genitourinary Syndrome of Menopause

Recruiting NCT04444440

Antibiotic Prophylaxis for Bladder Botox

Phase IV Interventional Canada

Idiopathic Overactive Bladder · Postoperative Urinary Tract Infection

Recruiting NCT06689163

A Study for the Treatment of Metastatic Prostate Cancer With HRS-1167 Tablets Combined With Abiraterone Acetate Tablets and Prednisone

Phase I / Phase II Interventional China

Prostate Cancer

Recruiting NCT06255223

A Study of Multimodal Radiotherapy for Renal Cell Carcinoma Progressed After Prior Immunotherapy

Phase II Interventional China

Renal Cell Carcinoma · Radiotherapy · Immune Checkpoint Inhibitor

Recruiting NCT05733104

A Study to Learn About the Study Medicine Zavicefta After it is Released Into the Markets in Korea

— Observational South Korea

Complicated Intra-abdominal Infection · Complicated Urinary Tract Infection · Hospital-acquired Pneumonia

Recruiting NCT05649943

Multimodal Approach in Patients With mHSPC. Randomized Trial of APA+ADT vs APA-ADT and Local Treatment

No phase Interventional Italy

Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Not yet recruiting NCT07016776

Uroflowmetry Curve Types and IPSS in Men With LUTS

— Observational —

Lower Urinary Tract Symptoms (LUTS) · Benign Prostatic Hyperplasia (BPH) · Voiding Dysfunction

Not yet recruiting NCT07152067

Stereotactic Focal Radiotherapy as an Alternative Treatment to Active Surveillance for Low and Intermediate Risk Prostate Cancer

Phase II Interventional Belgium

Macroscopic Tumor Visualized at MRI · Tumor Size Allowing Partial Prostate Treatment Volume · CAPRA SCORE ≤5

Recruiting NCT07149831

A Clinical Trial Evaluating the Safety and Tolerability, Biodistribution and Radiation Dosimetry, and Pharmacokinetics of Flotufolastat F-18 Injection in Healthy Chinese Adults

Phase I Interventional China

Prostate Cancer

Recruiting NCT06571708

Gemcitabine/Cisplatin Plus Cemiplimab With or Without Fianlimab in Localized Muscle-invasive Bladder Cancer (NeoSTOP-IT)

Phase II Interventional United States

Bladder Cancer · Muscle-Invasive Bladder Carcinoma

Recruiting NCT05519241

A Phase I Intravesical PPM Therapy for NMIBC

Phase I Interventional United States

Non-muscle-invasive Bladder Cancer

Recruiting NCT05879653

Pembrolizumab and EV With Radiation Therapy for MIBC Patients (PEVRAD)

Phase II Interventional Japan

Bladder Cancer

Recruiting NCT04951817

68Ga-PSMA PET/CT for Ra223 Assessment

No phase Interventional Taiwan

Metastatic Prostate Cancer

Not yet recruiting NCT07149103

Stimulating Percutaneous Array for Urinary Reflex Control (SPARC)

No phase Interventional Australia

Over Active Bladder

Recruiting NCT05230511

Intravesical LGG VS Saline Bladder Wash RCT

Phase II Interventional United States

Spinal Cord Injuries · Neurogenic Bladder

Not yet recruiting NCT07146386

A Phase III Clinical Study of H077 Sustained-Release Tablets Compared With Silodosin Capsules in the Treatment of Benign Prostatic Hyperplasia

Phase III Interventional China

Benign Prostatic Hyperplasia · Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms

Not yet recruiting NCT06607783

PRostate Cancer Enhanced Diagnosis by Calibration Technology

— Observational United Kingdom

Prostate Cancers

Recruiting NCT06331013

CyberKnife Ultra-hypofractionated SBRT for Localized PROStatE cancEr

No phase Interventional Italy

Prostate Cancer

Not yet recruiting NCT07145216

Effect of Knack Pelvic Floor Contraction on Sexual Dysfunction

No phase Interventional Egypt

Stress Urinary Incontinence (SUI) · Sexual Dysfunction

Recruiting NCT06738303

Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer

Phase II Interventional United States

Metastatic Prostate Cancer · Metastatic Castration-resistant Prostate Cancer

Recruiting NCT06134232

Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T

Phase II Interventional United States

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Recruiting NCT06241846

A Phase II Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Patients With mCRPC

Phase II Interventional China

Metastatic Castration-resistant Prostate Cancer (mCRPC)

Recruiting NCT03825874

Research of the Consequences on the Digestive Tract Following the Proposed Treatments for a Urinary Infection in Children

— Observational France

Urinary Tract Infections · Urinary Tract Infections in Children

Recruiting NCT06714630

The PROSECCA Study, Answering New Questions in Prostate Cancer

— Observational United Kingdom

Prostate Cancer

Recruiting NCT07115992

Efficacy and Safety of Radical Prostatectomy (RP) With or Without Salvage Radiotherapy Versus RP With Extended Pelvic Lymph Node Dissection for Localized Intermediate- and High-risk Prostate Cancer With a Briganti Nomogram≥7%

No phase Interventional China

Prostate Cancer · Prostate Adenoma

Recruiting NCT06605508

Regenerative Injection of Stem Cells or Stem Cell-derived Exosomes for Erectile Dysfunction (RISE)

— Observational United Arab Emirates

Erectile Dysfunction · Erectile Dysfunction Associated With Type 2 Diabetes Mellitus · Erectile Dysfunction Following Radical Prostatectomy

Not yet recruiting NCT07142200

A Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin Combined With PD-1 Inhibitor and Radiotherapy as Bladder-preserving Therapy in Patients With Localized HER2-high Expressing Muscle-invasive Bladder Urothelial Carcinoma Following Maximal Transurethral Resection

Phase II Interventional China

Bladder (Urothelial, Transitional Cell) Cancer

Not yet recruiting NCT07026864

MRI-Guided Bladder Preservation Program For Patients With Muscle Invasive Bladder Cancer

No phase Interventional —

Muscle Invasive Bladder Cancer (MIBC)

Recruiting NCT06683846

Ivonescimab in the Treatment of Multiple Advanced Tumors

Phase II Interventional China

Pheochromocytoma/Paraganglioma · Rhabdomyosarcoma · Paget Disease, Extramammary

Not yet recruiting NCT07140588

Pilot Study of a New Nerve Grafting Method During Bladder Cancer Surgery to Help Preserve Erections.

No phase Interventional —

Bladder Cancer Requiring Cystectomy · Erectile Dysfunction Following Radical Prostatectomy

Enrolling by invitation NCT07140549

Survey of Patients Who Received Fertility Preservation Counseling and Underwent Testicular Tissue Cryopreservation Prior to Gonadotoxic Treatment During Childhood or Peripuberty

No phase Interventional Belgium

Satisfaction Survey · Fertility Perservation

Recruiting NCT07135102

A Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of [225Ac]Ac-PSMA-XT Injection in Patients With Metastatic Castration-resistant Prostate Cancer

Phase I Interventional China

Metastatic Castration-Resistant Prostate Cancer Patients

Recruiting NCT07056283

The Study of Urinary Biomarkers in Patients With Hypomagnesemia

— Observational United States

Hypomagnesemia

Recruiting NCT05319015

Neoadjuvant Lenvatinib and Pembrolizumab for IVC Tumor Thrombus

Phase II Interventional United States

Renal Cell Carcinoma

Recruiting NCT05194137

Biofeedback Versus Vaginal Palpation to Teach a Voluntary Pelvic Floor Muscle Contraction

No phase Interventional Brazil

Urinary Incontinence

Recruiting NCT06265519

Association of Urine BDNF and NGF With Lower Urinary System Parameters

No phase Interventional Turkey (Türkiye)

Benign Prostatic Hyperplasia With Outflow Obstruction · Lower Urinary Tract Obstructive Syndrome

Not yet recruiting NCT07134439

Identifying Fundamental Mechanisms of Skeletal Muscle Ageing in Older Men Undergoing Androgen Deprivation Therapy: a Feasibility Study

— Observational —

Sarcopenia · Prostate Cancer · Muscle Atrophy

Recruiting NCT06179654

Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate

No phase Interventional United States

Benign Prostatic Hyperplasia With Outflow Obstruction · Urinary Retention · Lower Urinary Tract Symptoms

Not yet recruiting NCT05576766

Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy

No phase Interventional China

Prostate Cancer · Robot-Assisted Laparoscopic Radical Prostatectomy · Enhanced Recovery After Surgery (ERAS) Protocol

Not yet recruiting NCT07133243

Testicular Torsion Evaluation by ultraSonography Technic Imaging

— Observational France

Testicular Torsion

Recruiting NCT04038502

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

Phase II Interventional United States

Metastatic Castrate Resistant Prostate Cancer · BARD1, BRCA1, BRCA2, BRIP1, CHEK1, FANCL, PALB2 · RAD51B, RAD51C, RAD51D, or RAD54L Mutations

Not yet recruiting NCT07132671

MRI-guided Brachytherapy and Salvage SBRT Program

No phase Interventional —

Prostate Cancer (Post Prostatectomy)

Recruiting NCT07015138

Comprehensive Versus Primary Tumor Radiotherapy in Oligometastatic Prostate Cancer

No phase Interventional China

Prostate Cancer · Oligometastatic Prostate Cancer