Lung cancer

3,760 trials in this section

Not yet recruiting NCT07231380

A Comparison of Cyclic Manual Direct Aspiration Thrombectomy (Plunger Technique) vs. Static Manual Direct Aspiration Thrombectomy for Treatment of Acute Large Vessel Occlusion Stroke

No phase Interventional —

Acute Ischemic Stroke Patients · Large Vessel Occlusion

Not yet recruiting NCT07594834

Clinical Study on the Effects of Pulmonary Vessels on Cryoablation and Preventive Embolization Strategies

No phase Interventional —

Lung Cancer

Not yet recruiting NCT07596732

Statewide Unified Network for Remote Intervention of Strength and Exercise

No phase Interventional —

Gastric Cancer (Diagnosis) · Esophagus Cancer · Pancreas Cancer

Recruiting NCT06898333

Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cancer Screening

— Observational United States

Lung Cancer · Cancer of the Lung

Not yet recruiting NCT07597187

Clinical Utility of LIBS Multi-Element Imaging and the IFF Algorithm in Chronic Lung Diseases

— Observational —

Interstitial Lung Diseases (ILD) · Pulmonary Emphysema · Chronic Lung Diseases

Recruiting NCT06159660

Ventilation Using Radiographic Examination: Functional Lung Imaging Techniques for the Reduction of Toxicity in Functional Avoidance Radiation Therapy

— Observational Australia

Lung Neoplasm

Not yet recruiting NCT07595796

An Exploratory Study on Triple Inhaler Therapy in Patients With Early Lung Function Impairment

No phase Interventional —

Preserved Ratio Impaired Spirometry (PRISM)

Not yet recruiting NCT07596524

Analysis of Different Second Line Treatment in Advanced NSCLC Patients Progressing After 1st Line Immune Checkpoint Inhibitor Therapy

— Observational China

Lung Cancer (NSCLC)

Recruiting NCT07596121

Serplulimab Monotherapy in Elderly Patients With NSCLC and PD-L1 TPS ≥ 50%

Phase II Interventional China

NSCLC (Non-small Cell Lung Cancer)

Recruiting NCT05030207

Respiratory Adaptive Computed Tomography: Feasibility Study on Real-Time Gated 4DCT for Lung Cancer Radiotherapy

No phase Interventional Australia

Lung Cancer

Recruiting NCT06127654

Ventilation Imaging to Improve the Quality of Life for Patients With Lung Cancer Treated With Radiation Therapy

Phase III Interventional Australia

Lung Cancer

Recruiting NCT07154706

Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)

Phase III Interventional United States, Canada +1

Non-small Cell Lung Cancer (NSCLC)

Not yet recruiting NCT07595120

Application of Electromagnetic Navigation System in Pulmonary Nodule Localization

No phase Interventional China

Pulmonary Nodules · Early-Stage Lung Cancer

Recruiting NCT05431270

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

Phase I / Phase II Interventional United States

Non Small Cell Lung Cancer · Pancreatic Ductal Adenocarcinoma

Recruiting NCT06503146

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

Phase II Interventional United States

Sarcoma · Small Cell Lung Cancer or Extrapulmonary Neuroendocrine Cancer (EP-NEC) · Mesothelioma

Not yet recruiting NCT07588347

Construction and Preliminary Evaluation of Dyadic Acceptance and Commitment Therapy for Couples With Fear of Lung Cancer Recurrence

No phase Interventional —

Lung Neoplasms · Acceptance and Commitment Therapy · Spouses

Recruiting NCT06431633

Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free.

Phase III Interventional Spain

Lung Diseases · Carcinoma, Non-Small-Cell Lung · Resectable Lung Non-Small Cell Carcinoma

Recruiting NCT06783647

A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]

Phase II Interventional China

Advanced Solid Tumour

Recruiting NCT04299945

Effects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease

No phase Interventional Canada

Interstitial Lung Disease

Recruiting NCT07594522

A Study of Ivonescimab in People With Non-Small Cell Lung Cancer

Phase I / Phase II Interventional United States

Non-Small Cell Lung Cancer

Recruiting NCT07094204

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Phase I Interventional United States, France +2

Solid Tumor · Non-Small-Cell Lung Cancer · Pancreatic Ductal Adenocarcinoma

Not yet recruiting NCT07593430

The Effect of Aromatherapy Massage-Based Sensory Stımulatıon Program on Cognıtıve and Sensory Functıon ın Intensıve Care Patıents

No phase Interventional —

Cognitive Sensory Perception Level · in Unconscious Patients · Lung Disaases

Recruiting NCT05885698

MYLUNG Consortium Part 3: Observational Study

— Observational United States

Carcinoma, Non-Small-Cell Lung

Not yet recruiting NCT07590596

Preoperative Decision-Making in Patients With Pulmonary Nodules Suspected of Lung Cancer

— Observational China

Pulmonary Nodule · Suspected Lung Cancer · Preoperative Decision-Making

Enrolling by invitation NCT06324110

Evaluating the Impact of Centralized Interventions on Lung Cancer Screening Adherence in Community Settings, ACCELL Trial

No phase Interventional United States

Lung Carcinoma

Not yet recruiting NCT07014878

A Study of DCTY1102 Injection in Participants With Advanced Solid Tumors

Phase I Interventional China

Colorectal Cancer · Lung Cancer · Pancreatic Cancer

Recruiting NCT03851445

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Phase II / Phase III Interventional United States

Previously Treated Non-Small Cell Lung Cancer

Recruiting NCT07309276

A Phase II Clinical Study Evaluating the Combination Therapy of JS212 in Patients With Advanced Lung Cancer

Phase II Interventional China

Advanced Lung Cancer

Not yet recruiting NCT07593872

XR-Assisted PET/CT Navigation for Cervical Lymph Node Dissection in Lung Cancer

No phase Interventional —

Non-Small Cell Lung Cancer · Lymph Node Metastasis · Supraclavicular Lymph Node Metastasis

Recruiting NCT05279040

Trikafta Exercise Study in Cystic Fibrosis

— Observational Canada

Cystic Fibrosis · Lung Diseases

Recruiting NCT06868836

Phase II Clinical Study of JS207 (PD-1/VEGF Bispecific Antibody) Combination Therapies in Patients With Driver Gene-Positive, Advanced Non-Small Cell Lung Cancer After Failure of TKI Therapy

Phase II Interventional China

Non-squamous Non-small Cell Lung Cancer

Recruiting NCT04067830

Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

Phase II Interventional United States

Stage I Lung Cancer AJCC v8 · Stage IA1 Lung Cancer AJCC v8 · Stage IA2 Lung Cancer AJCC v8

Recruiting NCT07394062

Real-World Comparison of Chemo-Immunotherapy Regimens in Metastatic NSCLC With PD-L1 <50% (ALCG-01)

— Observational Turkey (Türkiye)

Nonsmall Cell Lung Cancer, Stage IV · Metastatic Nonsmall Cell Lung Cancer

Not yet recruiting NCT07594470

Case-Based Learning for Bedside Lung Ultrasound Teaching in ICU

No phase Interventional China

Medical Education · ICU · Emergency Medicine

Recruiting NCT06018766

LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome.

Phase II Interventional United States

Bronchiolitis Obliterans Syndrome · Chronic Lung Allograft Dysfunction · Lung Transplantation

Recruiting NCT07160335

A Phase I Clinical Study to Evaluate the PK Profile, Efficacy, Safety and Immunogenicity of HLX17 vs. Keytruda® in Multiple Resected Solid Tumors

Phase I Interventional United States, China +2

Non-small Cell Lung Cancer · Melanoma · Renal Cell Carcinoma

Recruiting NCT05379985

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Phase I / Phase II Interventional United States

Non-small Cell Lung Cancer (NSCLC) · Colorectal Cancer (CRC) · Pancreatic Ductal Adenocarcinoma (PDAC)

Enrolling by invitation NCT07239557

Optimal Interval for Periodic Alveolar Recruitment Maneuvers Achieving 90% Lung Re-expansion During Intraoperative Ventilation

No phase Interventional China

Major Abdominal Surgery · Atelectasis · Lung-protective Ventilation

Not yet recruiting NCT07589101

5T4 Targeting Nanobody Probe for PET Imaging in Solid Tumors

No phase Interventional China

Lung Cancer · Breast Cancer

Recruiting NCT05724264

SingapOre Lung Cancer Screening Through Integrating CT With Other biomarkErs (SOLSTICE)

No phase Interventional Singapore

Lung Cancer

Recruiting NCT07588737

Multimodal AI-Guided Recovery Management After Lung Cancer Surgery

No phase Interventional China

Postoperative Care · Rehabilitation · Artificial Intelligence (Al)

Recruiting NCT03007030

Brentuximab Vedotin in Treating Patients With CD30+ Malignant Mesothelioma That Cannot Be Removed by Surgery

Phase II Interventional United States

CD30-Positive Neoplastic Cells Present · Malignant Mesothelioma

Recruiting NCT05773001

Macrophage Regulation of Ozone-Induced Lung Inflammation

Phase I Interventional United States

Respiratory Viral Infection

Recruiting NCT07591389

Promoting Radon Testing Among Mothers of Young Children

No phase Interventional United States

Lung Cancer (Diagnosis)

Not yet recruiting NCT07460440

SPARC - Screening for Lung Cancer With Platelets Via an AI-enabled RNA-based Classifier

— Observational United States

Lung Cancer · Lung Nodule

Recruiting NCT03800017

Skeletal Muscle Function in Interstitial Lung Disease

No phase Interventional Canada

Interstitial Lung Disease · Idiopathic Pulmonary Fibrosis · Hypersensitivity Pneumonitis

Recruiting NCT06172478

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Phase II Interventional United States, Australia +14

Advanced Solid Tumor · Melanoma · Head and Neck Cancer

Recruiting NCT04977453

GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors

Phase I / Phase II Interventional United States, South Korea

Advanced Solid Tumor · Metastatic Solid Tumor · Cervical Cancer

Recruiting NCT06535074

Lung Function Monitoring During Hypoxemia Episodes

— Observational United States

Hypoxemia of Newborn

Recruiting NCT04296071

Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

— Observational United States

Lung Injury · Cardiopulmonary Bypass

Recruiting NCT04469842

Early Use of Long-acting Tacrolimus in Lung Transplant Recipients

Early Phase I Interventional United States

Lung Transplant; Complications

Not yet recruiting NCT07590440

Indian Lung Screening Trial

No phase Interventional India

Lung Cancer

Recruiting NCT07332858

First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion

Phase I / Phase II Interventional China

Malignant Pleural Effusions (Mpe) · Non Small Cell Lung Cancer

Not yet recruiting NCT07326592

Phase 4, Double-blind Study Evaluating the Response on Computed Tomography (CT) Lung Density Decline Rates of Respreeza / Zemaira Weekly for 3 Years in Adults With alpha1 Antitrypsin Deficiency (AATD)

Phase IV Interventional —

Alpha1 Antitrypsin Deficiency · Alpha1-Proteinase Inhibitor Deficiency · Emphysema

Recruiting NCT06486142

EGFR-mutated Lung Cancer in Randomized Investigator-Initiated Study

Phase III Interventional Sweden

Non-Small Cell Lung Cancer

Not yet recruiting NCT07542210

Barriers and Facilitators of Persistence With Adjuvant Osimertinib

— Observational China

Non-small Cell Lung Cancer

Recruiting NCT06284317

A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer.

Phase III Interventional Australia, Austria +8

Non Small Cell Lung Cancer

Recruiting NCT06922591

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Phase I / Phase II Interventional United States

PDAC · PDAC - Pancreatic Ductal Adenocarcinoma · NSCLC

Recruiting NCT07557225

18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors

No phase Interventional China

Clear Cell Renal Cell Cancer (ccRCC) · Urothelial Carcinoma (UC) · Colorectal Cancer

Recruiting NCT06417814

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Phase III Interventional United States, Australia +25

Metastatic Non-small Cell Lung Cancer

Recruiting NCT04789486

Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer

Phase I / Phase II Interventional United States

Non-small Cell Lung Cancer · Advanced Pancreatic Adenocarcinoma · Unresectable Pancreatic Cancer

Recruiting NCT07216404

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

Phase II Interventional United States

Lung Non-Small Cell Carcinoma · Unipolar Depression

Not yet recruiting NCT07588217

Ondansetron for the Prevention of Patient Self-Inflicted Lung Injury in Patients With ARDS - Pilot RCT

Phase II / Phase III Interventional Canada

ARDS (Acute Respiratory Distress Syndrome) · Invasive Mechanical Ventilation · Patient-Self Inflicted Lung Injury

Recruiting NCT07586826

Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gynecologic, Breast, or Lung Solid Tumors

Phase II Interventional China

Persistent Isolated Chemotherapy-Induced Thrombocytopenia · Chemotherapy-Induced Thrombocytopenia · Gynecologic Cancers

Recruiting NCT03694236

Concurrent Neoadjuvant Chemoradiotherapy Plus Durvalumab (MEDI4736) in Resectable Stage III NSCLC

Phase I / Phase II Interventional South Korea

Potentially Resectable Stage II/IIIa NSCLC

Not yet recruiting NCT07575880

Screening for Obstructive Respiratory Disorders in the General Population During the "Mai Poumon 2026" Prevention Campaign: Prevalence and Impact on the Care Pathway

— Observational —

Chronic Obstructive Lung Disease · Airflow Obstruction

Recruiting NCT06574581

ADSCs Therapy in Patients With CTD-ILD

Phase I / Phase II Interventional Taiwan

Connective Tissue Diseases · Interstitial Lung Disease

Recruiting NCT07489716

A Phase II Clinical Trial of SHR-1826 for Non-Small Cell Lung Cancer

Phase II Interventional China

Non-Small Cell Lung Cancer

Recruiting NCT07038343

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

Phase I / Phase II Interventional United States

Solid Tumor Cancer · Locally Advanced · Metastatic Solid Tumors

Recruiting NCT05834413

Clinical Study on the Prevention of Driver Gene Negative Ib-IIIb Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

No phase Interventional China

Lung Cancer

Not yet recruiting NCT07583316

A Phase 1 First-in-Human Study of CRPA1A2, a MAGE-A1/HLA-A*02:01 Bispecific T-Cell Engager, in Patients With Solid Tumors

Phase I Interventional China

Lung Cancer (Locally Advanced or Metastatic) · Esophagus Cancer · Head and Neck Cancer

Not yet recruiting NCT06982222

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

Phase I Interventional —

Anatomic Stage IV Breast Cancer AJCC v8 · Metastatic Breast Carcinoma · Metastatic Lung Non-Small Cell Carcinoma

Recruiting NCT07109154

DeniLA: Comprehensive Demographics and Clinical Profile of NSCLC Patients: Analyzing Guideline-Concordant Care in First-line Treatment Patterns

— Observational Brazil

Lung Neoplasms

Not yet recruiting NCT07582822

JH021 in Patients With Advanced Solid Tumors or EGFR-Mutant NSCLC

Phase I Interventional China

Advanced Solid Tumor

Recruiting NCT06673329

Brodalumab in the Treatment of Immune-Related Adverse Events

Phase I Interventional United States

Breast Cancer · Esophageal Cancer · Kidney Cancer

Recruiting NCT07436598

3D Virtual Resection for Predicting Lung Function in VATS

— Observational Taiwan

Non-small Cell Lung Cancer · Lung Cancer · Lung Neoplasms

Not yet recruiting NCT07376382

A Phase Ⅲ Clinical Study of SYS6010 in Combination With Osimertinib in Patients With Locally Advanced or Metastatic NSCLC

Phase III Interventional —

NSCLC

Recruiting NCT06437977

Neoadjuvant Therapy of SBRT Sequencial With Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC Patients(neoR-TORCH)

Phase III Interventional China

Stage II-III Non-small Cell Lung Cancer

Recruiting NCT07583511

Teniposide, Cisplatin and Serplulimab for Treatment of ES-SCLC, a Randomized Controlled Study

Phase II Interventional China

Small-cell Lung Cancer

Recruiting NCT07444437

A Phase II Trial of LM103 for Adjuvant Treatment in Patients With Non-small Cell Lung Cancer

Phase II Interventional China

Non-Small Cell Lung Cancer

Recruiting NCT05492682

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

Phase I Interventional Germany, Italy

Melanoma (Skin) · Triple-Negative Breast Cancer · Non-Small Cell Lung Cancer

Recruiting NCT07561723

IMP3-saRNA Vaccine in Advanced NSCLC

Phase I Interventional China

Non-Small Cell Lung Cancer

Recruiting NCT06476132

Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients

Phase II Interventional United States, Canada

Lung Transplant

Recruiting NCT07230405

A Phase II Study of SKB571 in Patients With Lung Cancer

Phase II Interventional China

Lung Cancer (Non-Small Cell)

Recruiting NCT06132698

Immune Checkpoint Inhibitors Intrathecal Injection in Patients With Leptomeningeal Metastases in NSCLC

Phase II Interventional China

NSCLC Associated With Leptomeningeal Metastases

Not yet recruiting NCT07579806

Dexmedetomidine Nasal Spray on Postoperative Delirium in Elderly Thoracoscopic Lung Resection Patients

Phase IV Interventional —

Postoperative Delirium (POD)

Recruiting NCT05351788

SKB264 Combinatiton Therapy in Patients With Advanced or Metastatic Non-small Cell Lung Cancer.

Phase II Interventional China

Non-small Cell Lung Cancer

Recruiting NCT07085091

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

Phase I Interventional United States

NSCLC (Advanced Non-small Cell Lung Cancer) · HNSCC · CRC (Colorectal Cancer)

Recruiting NCT05918302

Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus.

Phase III Interventional Belgium, France +2

Neuroendocrine Tumors · Lung Neuroendocrine Neoplasm · Thymus Neoplasms

Recruiting NCT07451899

TB Type and Spirometry Result vs. Functional Capacity Based on 6MWT in People With Post-TB Lung Disease

— Observational Indonesia

Post Tuberculosis · Lung Disease · Functional Capacity

Not yet recruiting NCT07570888

This is a Trial Designed to Evaluate the Combination of Nerandomilast With Mycophenolate Across a Wide Variety of Pulmonary Fibrosis Subtypes, With the Aim of Providing Clinicians With Assurance That This is an Appropriate Therapeutic Combination.

Phase IV Interventional —

Pulmonary Fibrosis · Interstitial Lung Disease (ILD)

Recruiting NCT07576595

Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans

No phase Interventional United States

Lung Cancer Screening · Tobacco Use Disorder · Smoking Cessation

Recruiting NCT07524114

Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)

— Observational Canada

Breast Cancer · Lung Cancer · Melanoma

Recruiting NCT06644144

P4O2 ILD Extension

— Observational Netherlands

Interstitial Lung Disease · Pulmonary Fibrosis · Interstitial Lung Fibrosis

Recruiting NCT06512935

Ventilator Pressure and Optimization of Compliance and Hemodynamics

No phase Interventional United States

Bronchopulmonary Dysplasia · Pulmonary Hypertension Due to Lung Diseases and Hypoxia · Extreme Prematurity

Recruiting NCT07329322

Phase II Study of Sacituzumab Tirumotecan in Combination With Osimertinib or Sacituzumab Tirumotecan for Neoadjuvant Treatment in Patients With Resectable Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

Phase II Interventional China

Non-Small Cell Lung Cancer

Recruiting NCT07578545

The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores

— Observational Turkey (Türkiye)

Thoracic Surgery · Videoassisted Thoracoscopic Surgery,One-lung Ventilation · Regional Anaesthesia

Not yet recruiting NCT06534528

Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Interstitial Lung Disease

Phase I Interventional —

Interstitial Lung Disease

Recruiting NCT06910956

Deep Learning Using Chest X-Rays to Identify High Risk Patients for Lung Cancer Screening CT

No phase Interventional United States

Lung Cancer · Health Screening · Early Cancer Detection

Recruiting NCT05363280

Phase 2 Study for the Patient, Who Has Diagnosed With Small Cell Lung Cancer (SCLC) or Non Small Cell Lung Cancer (NSCLC) or Renal Cell Carcinoma (RCC) and Finished the First Line Stand Treatment , Need More Treatment

Phase II Interventional United States, Spain

Small Cell Lung Cancer · Renal Cell Carcinoma (RCC) · Non-Small Cell Lung