Recruiting NCT05732480
Influence of Gut Microbiome in Gallstone Disease
Gall Stone · Gall Stones, Common Bile Duct · Pancreatitis
GI & liver
8,202 trials in this section
Not yet recruiting NCT06106100
Anti-reflux Mucosal Ablation Therapy Randomized Sham Control Trial for Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease
Not yet recruiting NCT06255912
Clinical Trial for Advanced or Metastatic Pancreatic Cancer
Pancreas Cancer
Not yet recruiting NCT06272162
Locally Advanced Pancreatic Cancer After Systemic Therapy: Ablative MR-guided Radiotherapy
Locally Advanced Pancreatic Adenocarcinoma
Recruiting NCT06270017
Evaluation of Metastatic Disease and Oncological Treatment in Patients With Colon Cancer Using Zebra Fish Avatars
Colon Cancer
Recruiting NCT06266832
The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma
Rectal Adenocarcinoma
Recruiting NCT04886635
Surgery As Needed for Oesophageal Cancer - 2
Cancer of Esophagus
Recruiting NCT06265350
Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases
Hepatocellular Carcinoma · Liver Cancer Stage IV · Pulmonary Metastases
Recruiting NCT06057350
Surgery Versus Endoscopic Resection for Incompletely Removed Early Colon CAnceR
Treatment Side Effects · Colorectal Cancer
Not yet recruiting NCT06227845
Preterm Infant Intestinal Microbiota Development and Maternal Fecal Transplant
Microbial Colonization
Not yet recruiting NCT05807646
Reduced Dissemination of Tumor Cells With Primary Ligation of the Inferior Mesenteric Vein in Rectal Cancer Patients.
Rectal Cancer
Recruiting NCT05007132
Trifluridine/ Tipiracil Plus Panitumumab Versus Trifluridine/ Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Not yet recruiting NCT06250413
Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With Antibiotics
Microbial Colonization · Antibiotic Side Effect
Recruiting NCT03222895
Distribution of Lymph Node Metastases in Esophageal Carcinoma
Esophageal Neoplasms · Lymph Node Metastases
Recruiting NCT05988814
Trial Evaluating the Efficacy and the Safety of FOLFIRINOX3 Treatment in Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer in First Line of Chemotherapy
Metastatic Pancreatic Cancer
Recruiting NCT06254521
The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer
Rectal Cancer · Rectal Cancer Stage II · Rectal Cancer Stage III
Recruiting NCT04815525
The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong
Colorectal Neoplasia · Colorectal Cancer
Not yet recruiting NCT06160271
Study of Liver Fibrosis Stage Assessment by Fibroblast Activation Protein Imaging in Patients With Biopsy for Suspected or Proven Nonalcoholic Steatohepatitis
Non-alcoholic Steatohepatitis
Recruiting NCT05912075
Preoperative Radiotherapy And ASTX660 in Rectum Cancer
Locally-advanced Rectal Cancer
Recruiting NCT05794048
METabolic PROFILE of Hepatocarcinoma and Pancreatic Tumors
Hepatocarcinoma · Pancreatic Tumor
Recruiting NCT06245330
A Phase I/II Study of AST-001 in Subjects With Advanced Solid Tumors
Solid Tumor · Pancreatic Cancer
Recruiting NCT01479608
Liver Transplantation and Colorectal Cancer
Colorectal Cancer · Liver Metastasis
Recruiting NCT06236568
Impact of Graft Reconditioning With Hypothermic Machine Perfusion on HCC Recurrence After Liver Transplantation
Hepatocellular Carcinoma · Liver Transplant; Complications
Recruiting NCT05678270
A Study of ICP-192 in Patients With FGFR2-Rearranged Unresectable or Metastatic Intrahepatic Cholangiocarcinoma
Intrahepatic Cholangiocarcinoma (ICC)
Recruiting NCT05515315
Induction Tislelizumab Combined With Chemotherapy Followed by Definitive Chemoradiotherapy in the Treatment of Locally Unresectable Esophageal Squamous Cell Carcinoma
Immunotherapy Esophagus Cancer
Recruiting NCT02215889
Partial Liver Segment 2/3 Transplantation Study
Colorectal Cancer
Recruiting NCT06244225
HAIC (Hepatic Artery Infusion Chemotherapy，HAIC）Plus Sintilimab and Donafenib in the First-line Treatment of Unresectable Hepatocellular Carcinoma
Hepatocellular Carcinoma
Recruiting NCT03494946
Liver Transplantation Compared to Chemotherapy in Patients With ColoRectal Cancer
Liver Metastases · Colorectal Cancer
Not yet recruiting NCT06241469
Efficacy and Safety of Sintilimab Combined With Nab-paclitaxel and Tegio (aTS) as First-line Treatment of Unresectable Locally Advanced, Recurrent or Metastatic Adenocarcinoma of Gastric and Gastroesophageal Junction，a Phase II Clinical Study
Gastric Cancer · GastroEsophageal Cancer · Adenocarcinoma
Recruiting NCT06059495
Watch-and-Wait Approach With Dostarlimab in Localized dMMR/MSI-H Gastric Cancer: GERCOR Phase II Study
Adenocarcinoma - GEJ · Gastric Adenocarcinoma
Recruiting NCT06242067
Second-line Treatment of Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Enrolling by invitation NCT06242613
National Multicenter Cohort Study of Robot-Assisted Gastrectomy Versus Laparoscopy in Gastric Cancer
Gastric Cancer
Not yet recruiting NCT06234072
Comparing Astragalus Plus Gemcitabine to Gemcitabine Alone as Neoadjuvant Treatment for Pancreatic Cancer Patients
Pancreatic Cancer
Recruiting NCT06163729
Camrelizumab Combined With Chemotherapy and Radiotherapy Perioperative Treatment of Esophageal Gastric Junction Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma (Siewert II-III)
Not yet recruiting NCT06238167
Tislelizumab Plus Chemotherapy as Postoperative Adjuvant Therapy in Elderly Patients With LA GC/GEJC
Gastric Cancer
Recruiting NCT06220617
Multi-omics Study for Early Detection of Colorectal Cancer (MOED-CRC)
Colorectal Cancer · Adenomatous Polyps · Adenoma
Not yet recruiting NCT05745168
Pilot Implementation of HIV Self-testing Delivery in Private Pharmacies Combined to a Respondent Driven Sampling Method to Improve HIV Testing for MSM and TGW in Phnom Penh - ANRS 0100s
HIV Infections
Not yet recruiting NCT06230432
Exploring the Mechanism of Severe Acute Pancreatitis Based on Metagenomics, Metabolomics and Proteomics
Acute Pancreatitis
Recruiting NCT05450991
Long-term Qualitative and Quantitative Outcomes of Children With Hirschsprung's Disease and Anorectal Malformations
Hirschsprung Disease · Anorectal Malformations
Not yet recruiting NCT06231576
Digital Home-Based Prehabilitation Before Surgery
Cancer Colorectal · Frailty · Surgery
Recruiting NCT06226857
Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer
Colorectal Neoplasms · Chemotherapy Effect · Molecular Sequence Variation
Recruiting NCT06229041
Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi)
Rectal Cancer
Not yet recruiting NCT06229197
Billroth II With Braun Anastomosis After Radical Distal Gastrectomy for Gastric Cancer
Gastric Cancer · Surgery · Anastomosis
Recruiting NCT05918094
Comparing Modified XELOX Plus Sintilimab With Standard XELOX Plus Sintilimab in First-line Treatment for HER2-negative Gastric/Gastroesophageal Junction Adenocarcinoma
Gastric Cancer
Not yet recruiting NCT06225609
No Stoma VS Ghost Stoma in Patients Undergoing Total Mesorectal Excision for Rectal Cancer
Rectal Neoplasms
Recruiting NCT05746897
A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors
Ovarian Cancer · Melanoma · Triple Negative Breast Cancer
Not yet recruiting NCT06222944
Anlotinib, TQB2450 (PD-L1 Inhibitor), and Albumin-bound Paclitaxel Regimens in the Treatment of GC/GEJA
Gastric Cancer · Adenocarcinoma of Esophagogastric Junction
Recruiting NCT04282083
Protocol ITANET - Registry
Gastro-entero Pancreatic Neuroendocrine Tumors
Recruiting NCT06222255
The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)
Low Anterior Resection Syndrome · Rectal Cancer · Insomnia
Recruiting NCT06098547
LIver Transplantation for Non-Resectable Intrahepatic CholAngiocarcinoma (LIRICA)
Intrahepatic Cholangiocarcinoma
Recruiting NCT06218810
Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer
Metastatic Colorectal Cancer · Microsatellite Stable Colorectal Carcinoma · RAS Mutation
Recruiting NCT04936581
Patient Reported Outcomes Following Cancer of the Rectum
Sphincter Ani Incontinence · Rectal Cancer
Not yet recruiting NCT06218888
A Phase II Clinical Study of the Efficacy and Safety of Tislelizumab Combined With Fruquintinib and Chidamide in the Treatment of Unresectable or Advanced Microsatellite Stabilized (MSS/pMMR) Colorectal Cancer With Liver Metastases
Colo-rectal Cancer
Recruiting NCT06219096
Application of ICG@HSA Complexes in Fluorescence Image-Guided Laparoscopic Anatomical Liver Resection
Malignant Tumor of Liver · Randomized Controlled Trial
Recruiting NCT05967910
The Effect of Chronic Stress on Efficacy of ICIs in Esophageal Cancer Patients (STRESS-ESCA Study)
Esophageal Cancer · Immunotherapy
Not yet recruiting NCT06217042
HR070803 in Combination With Oxaliplatin, 5-fluorouracil/LV Versus GX as Adjuvant Therapy for Pancreatic Cancer
Pancreatic Cancer
Not yet recruiting NCT06212115
Anti-infection Therapy Based on mNGS Etiological Diagnosis and Infection After Liver Transplantation
Infection
Recruiting NCT06212635
Hemostasis in Liver Cirrhosis and Hepatocellular Cancer
Hemostasis in Decompensated Liver Cirrhosis · Inflammation in Decompensated Liver Cirrhosis
Not yet recruiting NCT06213519
HIPEC Combined With SOX and Sintilimab in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis
Peritoneal Metastases · Gastric Cancer
Not yet recruiting NCT06192680
Liposomal Irinotecan and Capecitabine Plus Bevacizumab as Second-line Therapy in Metastatic Colorectal Cancer
Colorectal Cancer
Not yet recruiting NCT06210360
Perioperative Treatment in High-risk Resectable Pancreatic Cancer With NALIRIFOX
Pancreatic Cancer
Recruiting NCT02735057
Chemoradiotherapy in Elderly Patients With Oesophagus Cancer
Oesophagus Cancer · Elderly Patients
Recruiting NCT05265169
Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM)
Colorectal Liver Metastases
Recruiting NCT05872685
Perioperative Chemotherapy Combined With Serplulimab or Placebo for pMMR Locally Advanced Gastric Adenocarcinoma (FOCUS-05)
Adenocarcinoma of the Stomach · Adenocarcinoma of Esophagogastric Junction · Proficient Mismatch Repair
Recruiting NCT06123494
SHR-A1811 for Subjects With Her2-positive Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on or After First-line Anti-HER2 Therapy-containing Regimen
HER2-positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
Not yet recruiting NCT06190080
Outcome of Children With Eosinophilic Esophagitis
Esophagitis, Eosinophilic
Recruiting NCT06205472
Phase II Study of Adjuvant SIB Radiotherapy Following Narrow-Margin Hepatectomy in Patients With HCC.
Hepatocellular Carcinoma · Narrow Margin · Radiotherapy
Recruiting NCT06204484
MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer
Colorectal Cancer
Not yet recruiting NCT06204939
Extended Pouch Gastric Bypass vs One-anastomosis Gastric Bypass in Patients With BMI≥45
Bariatric Surgery Candidate
Recruiting NCT06190665
DEB-TACE With Visualable Microspheres Versus PVA Microspheres for HCC
Hepatocellular Carcinoma
Recruiting NCT06201065
FOLFOX-HAIC Plus Lenvatinib and Toripalimab vs. FOLFOX-HAIC Plus Lenvatinib for Advanced Hepatocellular Carcinoma: a Randomized Controlled and Double-blind Trial
Hepatocellular Carcinoma
Recruiting NCT05245474
Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer
Locally Advanced Rectal Cancer
Not yet recruiting NCT06196931
Clinical Value of DWI-ADC Matching in the Short-term Prognosis of Wilson's Disease
Hepatolenticular Degeneration; Wilson
Not yet recruiting NCT06196775
A Study of Cadonilimab Combined With AK112 as Second-line Therapy in Patients With Advanced Hepatocellular Carcinoma
Hepatocellular Carcinoma
Recruiting NCT05140746
Prediction of Neoadjuvant Chemotherapy Efficacy in Locally Advanced Gastric Cancer
Gastric Cancer
Not yet recruiting NCT06195670
Clinical Study of Short-course Radiotherapy Followed by Fruquintinib Plus Sintilimab vs Bevacizumab Plus Capecitabine as First Line Treatment in Advanced mCRC
CRC · Metastatic Colorectal Cancer · Metastatic Colorectal Adenocarcinoma
Recruiting NCT05403242
RC48-ADC Combined With S-1 for First-line Treatment of Advanced Gastroesophageal Adenocarcinoma With Moderate Expression of HER2
Advanced Gastroesophageal Adenocarcinoma
Recruiting NCT06194708
Reasons for Non-reversal of Temporary Stomas After Surgeries of Mid-low Rectal Cancer （NORESTO Study）
Rectal Cancer
Not yet recruiting NCT06195111
A Real-world Study of Trifluridine/Tipiracil Containing Regimen for the Treatment of Patients With mCRC (REFLECT Study)
Metastatic Colorectal Cancer
Not yet recruiting NCT06195904
Genomic Profiling of Pancreatic Cystic Tumors
Pancreatic Cyst
Recruiting NCT06190639
A Clinical Study of Sintilimab as Adjuvant Therapy in Node-positive ESCC
Esophageal Squamous Cell Carcinoma
Recruiting NCT06189898
Functional Imaging to Identify Radiosensitive Esophageal Cancer - a Biomarker Validation Study
Esophagus Cancer
Not yet recruiting NCT05312853
Evaluating the Diagnostic and Predictive Value of Non-invasive Tests (NITs) on the Progression of Chronic Liver Disease.
Chronic Liver Disease
Not yet recruiting NCT06188273
Impact of Skeletal Muscle Quality and Loss on the Outcome of Liver Transplantation
Liver Transplantation · Muscle Loss · Muscle Quality
Enrolling by invitation NCT06160557
A Clinical Study of Non-curative Resection Plus Radiotherapy After Endoscopic ESD for Superficial Esophageal Squamous Cell Carcinoma
Esophagus Cancer · Radiotherapy · Endoscopic Mucosal Resection
Recruiting NCT05089604
Tacrolimus Associated Tremors in Liver Transplantation: Immediate-Release Versus Extended-Release Formulations
Liver Transplantation · Immunosuppression · Neurotoxicity
Recruiting NCT06185621
The Effect of Aspirin on Recurrent Acute Pancreatitis
Recurrent Acute Pancreatitis · Prevention · Aspirin
Enrolling by invitation NCT04066608
Prevalence of Advanced Fibrosis in Patients Living With HIV
Fatty Liver Disease
Recruiting NCT06176885
Efficacy and Safety of Combined With Immunotherapy After Induction Therapy With Chemotherapy and Targeted Therapy in the First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer
Colorectal Cancer
Recruiting NCT05833594
Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs for Local Advanced Patients With Inoperable Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma · Chemoradiotherapy · Immunonutrition
Not yet recruiting NCT04889742
Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors
Recurrent Cancer · Prostate Cancer · Cervical Cancer
Recruiting NCT06181396
Time of Oxytocin Initiation at 2nd Stage of Labor and Adverse Outcomes
Delivery Complication · Cesarean Delivery Affecting Fetus
Recruiting NCT06061146
Tislelizumab Plus Concurrent Chemoradiation in Older With ESCC
Esophageal Cancer
Not yet recruiting NCT04209842
Effectiveness Gastric Balloon in Obese Adolescents
Obesity, Morbid
Recruiting NCT06178315
EUS-guided Celiac Plexus Block vs. Sham in Chronic Pancreatitis
Chronic Pancreatitis
Recruiting NCT06168786
Cadonilimab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With MSS CRC
Colorectal Cancer
Recruiting NCT05991102
Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With TAS-102 (Lonsurf) and Bevacizumab in Refractory Metastatic Colorectal Cancer
Refractory Metastatic Colorectal Cancer
Recruiting NCT06155318
68Ga-DOTATOC PET for the Evaluation of Gastroenteropancreatic Neuroendocrine Tumours
Gastroenteropancreatic Neuroendocrine Tumor
Not yet recruiting NCT06178211
Neoadjuvant Adebrelimab Plus Chemotherapy for Resectable ESCC: a Single Arm, Prospective Phase 2 Clinical Trial
Esophageal Squamous Cell Carcinoma
Recruiting NCT05427383
KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy
Stomach Cancer