Recruiting NCT06946745
Exploration of the Dynamic Changes and Mechanisms of the Immune Microenvironment in Advanced Colorectal Cancer Treated With IBI363 Combination Therapy
Immunotherapy
GI & liver
8,202 trials in this section
Recruiting NCT06946901
The Safety and Effectiveness of Hyperthermic Intraperitoneal Chemotherapy Combined With Intravenous Chemotherapy for Peritoneal Metastatic Pancreatic Cancer, a Phase II Clinical Trial
Hyperthermic Intraperitoneal Chemotherapy · Peritoneal Metastatic Pancreatic Cancer
Recruiting NCT06944587
A New Clinical Pathway for Personalized Management of Borderline Resectable and Locally Advanced Pancreatic Cancer
Locally Advanced Pancreatic Cancer · Borderline Resectable Pancreatic Cancer · Pancreatectomy
Not yet recruiting NCT06944327
Reduction of Complications Associated With PICC Management
Treatment Outcome · Vascular Access · Vascular Access Device
Not yet recruiting NCT06938282
An Exploratory Clinical Study of HRS-4642 in Combination With Immunotherapy and Chemotherapy for Pancreatic Cancer
Pancreatic Cancer
Recruiting NCT01984762
Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in the Treatment of Type 2 Diabetes Mellitus.
Obesity · Type 2 Diabetes · Bariatric Surgery
Enrolling by invitation NCT04065516
ARAT for Reflux Disease After Peroral Endoscopic Myotomy in Patients With Achalasia
Achalasia · Gastroesophageal Reflux
Not yet recruiting NCT06944496
A Study of Disitamab Vedotin Combined With Tislelizumab and Chemotherapy Versus Tislelizumab Combined With Chemotherapy in HER2-Low Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Gastric Carcinoma
Not yet recruiting NCT06941987
Evaluate the Clinical Feasibility of a Novel Neoantigen-Reactive CD8+ T Cell (NART) Detection Technology for Postoperative MRD Surveillance of Pancreatic Cancer
Minimal Residual Disease · Pancreatic Cancer Resectable
Recruiting NCT06822413
Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis
Cancer Diagnosis · Liver Cancer, Adult · Cancer Screening
Recruiting NCT06418659
A Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients
Advanced Hepatocellular Carcinoma
Not yet recruiting NCT06942663
Randomized Phase II Trial Evaluating DFS in The Absence of an Adjuvant Component of Perioperative Chemotherapy in Patients With Gastric Cancer
Gastric Cancer
Not yet recruiting NCT06935643
The Effect of Birth Ball and Perineal Massage on Perineal Pain, Perineal Trauma and Birth Satisfaction
Perineal Pain · Birth Satisfaction · Perineal Laceration, Tear, or Rupture During Delivery
Recruiting NCT06583993
A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α srRNA in Treating Advanced ICC Patients
Intrahepatic Cholangiocarcinoma
Not yet recruiting NCT06943690
Safety and Efficacy Study of Single-port Robotic Versus Multi-port Robotic Radical Rectal Cancer Surgery
Rectal Cancer · Surgery
Enrolling by invitation NCT06942312
Elucidating Hepatic Metabolism in Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease (NAFLD)
Recruiting NCT06621173
A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α SrRNA in Treating Metastatic CRC Patients
Metastatic Colorectal Cancer (mCRC)
Recruiting NCT04448028
Stop of Proton-pump Inhibitor Treatment in Patients With Liver Cirrhosis - a Double-blind, Placebo-controlled Trial
Liver Cirrhosis
Not yet recruiting NCT06162468
Feasibility Trial of EUS-PCA in IPMN Pancreatic Cysts
Intraductal Papillary Mucinous Neoplasm of Pancreas
Recruiting NCT05267379
An European Multi-centre Cohort Study for Unravelling Pharmacokinetic and Genetic Factors Underlying Post-ERCP Pancreatitis
Post-ERCP Acute Pancreatitis
Recruiting NCT06166576
Radioembolization as a Spearhead Treatment of Hepatocellular Carcinoma With Localized Portal Vein Tumor Thrombosis
Hepatocellular Carcinoma
Recruiting NCT06939569
An Observational Study of Inflammatory Bowel Disease (IBD) Patients With Non-alcoholic Fatty Liver Disease (NAFLD)
Inflammatory Bowel Disease (IBD) · Metabolic Dysfunction Associated Fatty Liver Disease
Recruiting NCT06555003
DEBIRI Plus Chemotherapy vs. Chemotherapy Alone in Colorectal Cancer Liver Metastases
Liver Neoplasm · Colorectal Cancer Metastatic
Recruiting NCT06940102
Real-World Study on Nano-Crystalline Megestrol Acetate for Cachexia in TKI-Treated Advanced Digestive Tumors
Cachexia · Digestive System Cancer · Gastric Cancer
Recruiting NCT05342194
Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study
Intrahepatic Cholangiocarcinoma
Recruiting NCT06798948
Effect of the Combined Application of Cynara Scolymus, Silybum Marianum, Curcuma Longa, and Glycyrrhiza Glabra in Improving Metabolic Associated Fatty Liver Disease : a Randomized Clinical Trial
Metabolic-associated Fatty Liver Disease (MAFLD)
Not yet recruiting NCT06938503
AG Plus Nimotuzumab Sequential Irreversible Electroporation Ablation for Locally Advanced Pancreatic Cancer
Pancreatic Cancer, Adult
Not yet recruiting NCT06931925
Recall of a Cohort of Subjects in the Mediterranean Area. Monitoring of Liver Diseases (NUTRIHEP 3).
Cohort Study
Not yet recruiting NCT05041335
Wet Heparinized Suction for Abdominal Cancer
Cancer of Pancreas · Cancer of Stomach · Cancer of Esophagus
Not yet recruiting NCT04760847
Intermittent Fasting for Pancreatitis
Pancreatitis · Pancreatitis, Acute · Pancreatitis, Chronic
Recruiting NCT05518643
Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and Outcomes
ERAS · Pancreas Cancer · Pancreas; Fistula
Not yet recruiting NCT06938451
Relationship Between FGF19 Overexpression and Disease Prognosis
Hepatocellular Carcinoma (HCC)
Not yet recruiting NCT06938490
Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy
Colorectal Cancer (CRC) · Surgery, Colorectal · Oncology
Recruiting NCT06584604
Calibration of Esophageal Balloon Catheter in Spontaneous and Mandatory Mechanical Ventilation
Intensive Care Unit · Mechanical Ventilation · Critical Illness
Recruiting NCT06925243
Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma
Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ]) · Neoadjuvant Therapy · Adjuvant Chemotherapy
Recruiting NCT06935708
Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery
Colorectal Carcinoma · Analgesia, Postoperative · Laparotomy
Enrolling by invitation NCT06936800
Pinaverium Bromide Preventing Post Extracorporeal Shock Wave Lithotripsy Pancreatitis and Painful (PBPEP)
Chronic Pancreatitis · Pancreatic Duct Stones
Not yet recruiting NCT06935734
Robotic Colonoscopy Using the Triton 4.0 System in Adults for Screening, Surveillance, and Diagnosis of Lower Gastrointestinal Conditions
Colonoscopy · Colorectal Cancer Screening · Colorectal Neoplasms
Recruiting NCT06935448
Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy
Pancreatectomy · Enhanced Recovery After Surgery · Pancreatic Cancer Resectable
Enrolling by invitation NCT06936488
A Prospective, Single Arm, Open Label, Phase II Clinical Study on the Efficacy and Safety of Ivonescimab (AK112) Combined With TAS-102 in the Treatment of Refractory MSS/pMMR Advanced Colorectal Cancer
MSS/pMMR Type Metastatic Colorectal Adenocarcinoma Patients
Not yet recruiting NCT06935175
A Study of SHR-1826 Monotherapy or in Combination With Immunotherapy in the Treatment of Advanced Hepatocellular Cancer
Hepatocellular Cancer
Recruiting NCT05239338
Preserving Fertility After Colorectal Cancer Study
Colorectal Cancer
Not yet recruiting NCT06933966
Evaluation of Efficacy and Safety De-escalation Versus Standard Adjuvant Chemotherapy in Patients With Low Risk Localized Gastroesophageal Adenocarcinoma
Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma · Non Metastatic Disease
Recruiting NCT06923345
Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)
Rectal Cancer · Neoadjuvant Therapies · Immune Checkpoint Therapy
Recruiting NCT06908382
Neoadjuvant QL1706 Therapy for ESCC
Locally Advanced Resectable Esophageal Squamous Cell Carcinoma
Not yet recruiting NCT06934824
Clinical Study of Double-Endoscopic Combined With Minimally Invasive Treatment for Early Gastric Cancer at Clinical Stage T1b
Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
Recruiting NCT06884761
Routine Activity and Preterm Delivery Risk in Women With a Short Cervix
Cervical Shortening
Not yet recruiting NCT06779474
Laparoscopic Associating Liver Partition With Portal Vein Ligation for Staged Hepatectomy (ALPPS) for Colorectal Liver Metastases (CRLM)
Colorectal Liver Metastases
Recruiting NCT05905640
One-stop PrEP Care Pathway to Simplify PrEP Delivery in Kenya: The One-Stop PrEP Care Project
HIV Infections
Not yet recruiting NCT06932289
Integrating Metabolic and Vascular Sensors to Monitor Cardiometabolic Disorders After Nutrition Interventions
NAFLD (Nonalcoholic Fatty Liver Disease)
Not yet recruiting NCT06903663
The Epidemiology of Patients Treated With ATZ+BEV in Real Life Setting
Hepatocellular Carcinoma (HCC)
Recruiting NCT06637163
Benmelstobart Combined With Radiochemotherapy as Neoadjuvant Treatment Iin ESCC
Esophageal Squamous Cell Carcinoma
Enrolling by invitation NCT06931808
Intestinal Microbiota Transplantation, Radiochemotherapy and Sintilimab in Localized Advanced Colon Cancer
Localized Advanced Rectal Adenocarcinoma
Recruiting NCT06932445
Effect of Malnutrition on Liver and Spleen Stiffness in Children
Malnutrition in Children · Liver Stiffness · Spleen Stiffness
Not yet recruiting NCT06931873
Neoadjuvant Radiochemotherapy Combined With QL1706 for Low Rectal Cancer
Rectal Cancer
Recruiting NCT05989477
At-home Breast Oncology Care Delivered With E-health Solutions
Patient Engagement · Patient Activation · Patient Reported Outcome Measures
Recruiting NCT06843889
A Phase II Study of Toripalimab Combined With Sequential Neoadjuvant Chemoradiotherapy in Patients With Esophageal Squamous Cell Carcinoma
Locally Advanced Esophageal Squamous Cell Carcinoma
Recruiting NCT06930573
A Study of AK112, a PD-1/ VEGF Bispecific Antibody, for Resectable Hepatocellular Carcinoma With High Recurrence Risk
HCC
Recruiting NCT04735835
Personalized Responses to Dietary Composition Trial 3
Diabetes · Heart Diseases · Diet Habit
Recruiting NCT06930118
The Aim of This Study is to Assess the Efficacy and Safety of Chidamide, Regorafenib in Combination With Iparomlimab and Tuvonralimab for the Treatment of Advanced Colorectal Cancer in Third-line Therapy and Subsequent Lines.
Advanced Colorectal Cancer in the Third-line Treatment and Beyond · pMMR/MSS Advanced Colorectal Cancer
Recruiting NCT06926374
Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery
Colorectal Carcinoma · Rectal Prolapse · Prostate Cancer (Adenocarcinoma)
Recruiting NCT06929949
The Effect of Different Digestive Tract Reconstruction Methods on Postoperative Quality of Life After Proximal Gastrectomy
Gastroesophageal Junction (GEJ) Cancer · Gastric Cancer
Not yet recruiting NCT06919796
mRNA Covid-19 Vaccine Immune Response Comparisons Using Different Delivery Routes
Evaluate Immune Responses Following mRNA COVID-19 Vaccine Administration Through Different Delivery Routes in Healthy Volunteers · SARS CoV-2
Recruiting NCT06925204
Natural Course and Therapeutic Effect of Chronic Pancreatitis
Chronic Pancreatitis
Enrolling by invitation NCT06927258
Application of Changyanning Granule in Endoscopic Resection of Colorectal Polyps
Colorectal Polyps
Recruiting NCT06927830
Frequency of Occurrence and Risk Factors of Postoperative Nausea and Vomiting During Elective C-section Under Spinal Anesthesia With Preventive Medication
Nausea and Vomiting, Postoperative · Cesarean Delivery · Spinal Anesthesia
Not yet recruiting NCT06928415
Efficacy and Safety of Liver Transplantation for Hepatocellular Carcinoma With Bile Duct Tumor Thrombus: a Single-arm, Multicenter, Prospective Study (HCC-BDTT in LT)
Liver Transplant · Hepatocellular Carcinoma · Bile Duct Tumor Thrombus
Recruiting NCT05169073
Virtual Reality Training for Laparoscopic Cholecystectomy
Virtual Reality · Gallbladder · Bile Duct Injury
Recruiting NCT06928584
Hypofractionated Radiotherapy Plus Immunotherapy Versus Conventional Radiotherapy in Locally Recurrent Rectal Cancer
Locally Recurrent Rectal Cancer
Not yet recruiting NCT06927401
Evaluate the Detection of Retained Gastric Contents and Assess Safety Using the Flower Capsule Endoscopy in Healthy Individuals and GLP-1 Receptor Agonist Users
Endoscopy, Digestive System · GLP1-R-related Disease
Recruiting NCT06844604
Carbon Footprint Assessment for Robotic, Laparoscopic and Open Colorectal Operations to Enhance Environmental Sustainability
Colorectal Operations
Not yet recruiting NCT06925074
Quantified Evaluation of Noninvasive System Delivering Microwave Energy for Unwanted Fat Reduction and Skin Tightening in Asians.
Facial Aging · Skin Laxity · Cheek Wrinkles
Recruiting NCT06406062
Artificial Intelligence-assisted System in Colonoscopy
Adenoma Colon Polyp
Recruiting NCT06847126
Empirical Intravenous Beta-Lactam Plus Metronidazole Vs Oral Cefixime Plus Metronidazole for the Treatment of Liver Abscess
Liver Abscess
Recruiting NCT06925997
Metabolic Effects of Endogenous Bile Acids After Gastric Bypass Surgery
Bariatric Surgery Candidate · Bile Acid, Elevated Serum · Glucose Metabolism Disorders
Not yet recruiting NCT06923176
Effect of Biejia-Ruangan Compound on Survival Rate and Recurrence Rate of Hepatocellular Carcinoma After Radical Treatment
Hepatocellular Carcinoma (HCC)
Recruiting NCT06685887
A Clinical Study Evaluating the Efficacy of Systemic Chemotherapy and Immune Checkpoint Inhibitors Combined With Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Gastric Cancer Patients With Peritoneal Metastasis
Gastric Cancer
Not yet recruiting NCT06923215
Glucose Disposal Rate as a Metric for Detection of Metabolic Associated Fatty Liver
MAFLD
Recruiting NCT06215404
Fluid Management Strategies on Blood Loss in Liver Transplantation
Liver Transplant
Enrolling by invitation NCT06923319
Learning Curves of Different Devices for Vaginal Birth on Mannequin
Forceps Delivery Affecting Fetus or Newborn · Ventouse Extraction;Liveborn · Birth; Forced
Recruiting NCT06923449
Gastric Cancer' Textbook Oncological Outcome and Tumor Board Performance
Stomach Neoplasm
Enrolling by invitation NCT06923020
Association of Nutritional Status With Immune Checkpoint Inhibitor Efficacy in Metastatic Metastatic Esophagogastric Cancer.
Gastric Neoplasm · Esophageal Adenosquamous Carcinoma
Not yet recruiting NCT06923475
Neoadjuvant Gemcitabine and Cisplatin in Combination With Perioperative Pembrolizumab Versus Upfront Surgery for Patients With Primary Resectable and Borderline Resectable Perihilar and Distal Cholangiocarcinoma
Extrahepatic Cholangiocarcinoma · Perihilar Cholangiocarcinoma · Distal Cholangiocarcinoma
Recruiting NCT06923150
A Randomised Clinical Investigation to Assess Efficacy of Low Volume Transanal Irrigation by Qufora® IrriSedo MiniGo Versus Conservative Treatment for Low Anterior Resection Syndrome Patients
Gastroenterology · LARS - Low Anterior Resection Syndrome · Rectal Cancer
Recruiting NCT06355427
The Effect of [18F] F-FAPI PET-CT on Management in Patients With Proximal Cholangiocarcinoma
Cholangiocarcinoma
Recruiting NCT06921668
Perioperative Dynamics of Energy Expenditure in Oesophagectomy Patients
Oesophagectomy
Recruiting NCT06718543
Neoadjuvant Short-Course Radiotherapy With or Without Chemotherapy and AK112 in Locally Advanced Rectal Cancer
Rectal Cancer
Recruiting NCT06867497
A Study to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety Between Administration of BR2021 and BR2021-1
Metastatic Adenocarcinoma of the Pancreas
Recruiting NCT06678919
AGMT Metastatic Colorectal Cancer Registry (mCRC) Third Line and Beyond
Metastatic Colorectal Cancer (mCRC)
Recruiting NCT06428617
Fundus Ablation Registry (Gastric Fundus Mucosal Ablation for Weight Loss)
Obesity
Recruiting NCT06760364
A Clinical Study of CHT102 in MSLN-Positive Advanced Pancreatic Cancer
Advanced Pancreatic Cancers
Recruiting NCT06252142
Study for Wait and Watch Suitable in Rectal Cancer
Rectal Neoplasms
Recruiting NCT04980287
Mesogastrium Metastasis in Colon Cancer
Colon Cancer
Recruiting NCT06251297
Feasibility and Benefits of Reflexology in the Prevention of Neuropathy Induced by Oxaliplatin in Colorectal Cancer
Colorectal Cancer
Not yet recruiting NCT06918886
Comparison of Liver Health in Psoriatic Arthritis Patients Using Anti-TNF or Anti-IL17 Treatments
Psoriatic Arthritis (PsA) · Liver Fibrosis · Liver Diseases
Not yet recruiting NCT06917833
Impact of Maternal Body Mass Index on Infant Hypoxic Events at Time of Delivery ,Cross-sectional Study.
Maternal Obesity · Hypoxia Neonatal
Not yet recruiting NCT06919120
The Study on the Effect of Different Administration Methods of Simethicone in Reducing Bubbles During Bowel Preparation
Colonoscopy
Recruiting NCT06909708
SIRT Versus cTACE for Unresectable HCC (CHANCE2506)
Unresectable Hepatocellular Carcinoma
Recruiting NCT06740357
Implementation of a Tumor Response Assessment Program Integrating the Shared Medical Decision Into the Organ Preservation Strategy for Rectal Cancer Patients
Rectal Cancer
Not yet recruiting NCT06919848
Oncolytic Virus H101 Combined With Lenvatinib Plus Toripalimab Compared With FOLFOX in Patients With Advanced Biliary Tract Cancer (OPTIONS-06)
Biliary Tract Cancer (BTC)