Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: enhanced recovery after surgery.
- Who it may be relevant to
- Registry conditions: Pancreatectomy, Enhanced Recovery After Surgery, Pancreatic Cancer Resectable. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Greece
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy; Experience From Two Referral Centers in Central Greece.
Overview
This study assesses whether patients with pancreatic cancer who undergo surgery experience improved outcomes following the implementation of a multidisciplinary care pathway, specifically an enhanced recovery after surgery (ERAS) program. This pathway includes various interventions in the preoperative, intraoperative, and postoperative care of these patients, all aimed at enhancing their health status and postoperative results.
Detailed description
This prospective observational study is conducted by the same surgical team at two high-volume pancreatic cancer referral centers in Greece.
Patients undergoing elective pancreatic surgery are prospectively enrolled and managed according to a standardized ERAS protocol (ERAS group).
A control group, which received standard perioperative care before the implementation of ERAS, was retrospectively selected and matched based on demographic and clinical parameters.
The primary study endpoint is the length of hospital stay (LOS), while secondary endpoints include 30-day mortality and morbidity.
Interventions
- Other enhanced recovery after surgery
ERAS group follows the enhanced recovery after surgery program which involves 20 elements
Primary outcome measures
- impact on length of stay [Time frame: within 30 days of surgery]
Secondary outcome measures (1)
- impact on overall morbidity [Time frame: within 30 days from surgery]
Eligibility criteria
Inclusion criteria
- adult patients
- diagnosis of pancreatic cancer
- elective open pancreatic surgery
Exclusion criteria
- age <18 years
- emergency pancreatic surgery
- other surgical procedures
- missing data
- lost to follow-up
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-control
Study locations
Greece · 1 center
- University of Thessaly — Larissa
Publications
- Cardini B, Primavesi F, Maglione M, et al. Outcomes following pancreatic resections-results and challenges of an Austrian university hospital compared to nationwide data and international centres. Eur Surg (2019) 51:81-89. https://doi.org/10.1007/s10353-019-0585-x
- Lau CS, Chamberlain RS. Enhanced Recovery After Surgery Programs Improve Patient Outcomes and Recovery: A Meta-analysis. World J Surg. 2017 Apr;41(4):899-913. doi: 10.1007/s00268-016-3807-4. PMID 27822725
Identifiers
NCT: NCT06935448 · UNIVERSITY OF THESSALY 2412