Recruiting NCT04863950
Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma
Glioblastoma
CNS tumors
876 trials in this section
Enrolling by invitation NCT02670161
Quality Improvement and Practice Based Research in Neurology Using the EMR
Brain Tumors · Epilepsy · Migraine
Not yet recruiting NCT07138001
Phase 2 Clinical Trial of KH617
Recurrent Glioblastoma
Recruiting NCT06018363
Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection
Brain Gliomas · High-Grade Gliomas · GBM
Enrolling by invitation NCT07130149
Sonodynamic-Chemoradiotherapy Integration in Glioblastoma
Glioblastoma (GBM)
Recruiting NCT07126821
A Vision-Language Foundation Model for Brain Disease Diagnosis From Multimodal Data
Brain (Nervous System) Cancers · Brain Arterial Disease · Neuro-Degenerative Disease
Recruiting NCT06385132
Psychological and Psychiatric prOfile in Glioblastoma and Head and Neck Cancer
Glioblastoma · Head and Neck Cancer
Recruiting NCT07121842
Glioblastoma Imaging for the Detection of Tumor Progression Using APTw-CEST MRI
Glioblastoma
Not yet recruiting NCT07120984
A Study to Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent IDH-mutant Astrocytoma or Oligodendroglioma
Glioma
Recruiting NCT07119294
Molecular Imaging of Cancer-associated Fibroblasts in Glioblastoma: a FAPI PET/MR Study.
Glioblastoma
Recruiting NCT03672721
IA Carboplatin + Radiotherapy in Relapsing GBM
Glioblastoma Multiforme · Relapse
Recruiting NCT07111195
Feasibility of ONCOhabitats for Surgical and Treatment Planning in IDH-Wildtype Glioblastoma (SINUE)
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Not yet recruiting NCT06617208
Prognostic IntraOperative Biomarkers ideNtification in Tumor rElatEd suRgery
Glioma · Glioblastoma (GBM) · Brain Tumor-Glioma
Recruiting NCT05180825
Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy
Grade 1 Glioma · Mixed Glio-neuronal Tumors · Pleomorphic Xanthoastrocytoma
Recruiting NCT06002711
Multi-Dimensional MRI Spatial Heterogeneity Analysis for Predicting Key Genes and Prognosis of High-Grade Gliomas: A Multi-Center Study
High-grade Glioma
Not yet recruiting NCT07109362
ERP-Based Research on the Modulation of Remimazolam on Working Memory and Brain Network Mechanisms in Glioma Patients
Remimazolam Mild Sedation · Healthy Brain and Glioma Brain
Recruiting NCT06356883
Intraarterial Carboplatin + Caelyx vs Intraarterial Carboplatin + Etoposide Phosphate for Progressing Glioblastoma
Glioblastoma Multiforme · Relapse
Not yet recruiting NCT07106008
Radiolabeled TSPO Targeted Molecular Probe in Glioma
Glioma (Any Grade) in the Brain
Recruiting NCT07105358
Visual Plasticity Following Brain Lesions
Visual Field Defect · Stroke · Hemianopia
Recruiting NCT07025018
Phase I Study of HMPL-306 for the Treatment of Gliomas With IDH1 and/or IDH2 Mutations
Gliomas Harboring IDH1 and/or IDH2 Mutations
Recruiting NCT06430424
Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma
Relapsed Cancer · Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Recruiting NCT06506578
Nausea Induced by Radiation of the Dorsal Vagal Complex for Benign Brain Tumors (NausiCAA)
Benign Brain Tumor
Recruiting NCT05929495
Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma
Glioblastoma, IDH-wildtype · Metformin · Malignancies
Recruiting NCT07066475
A Registry-Based Cohort Study on the Clinical Outcomes of Spinal Cord Glioma Resection Via the Dorsolateral Sulcus Approach
Spinal Cord Cancer · Spinal Cord Neoplasm · Spinal Cord Tumor
Recruiting NCT04523688
Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate in Glioblastoma
Glioblastoma · Vaccination
Recruiting NCT05909618
Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases
Advanced Glioblastoma · Metastatic Melanoma in the Central Nervous System · MGMT-Unmethylated Glioblastoma
Recruiting NCT06377033
Using the EHR to Advance Genomic Medicine Across a Diverse Health System
Genetic Predisposition · Paraganglioma · Pheochromocytoma
Recruiting NCT05609994
ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas
Low Grade Glioma of Brain
Recruiting NCT06501521
Non-invasive Brain Tumor Molecular Diagnostics and Monitoring
Brain Tumor
Recruiting NCT06092125
Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease
Alzheimer Disease · Parkinson Disease · Epilepsy
Recruiting NCT06099743
ASCENT Intervention for Brain Tumor Patients
Malignant Brain Tumor · Glioma · Coping Skills
Not yet recruiting NCT07061626
Determine Maximum Tolerated Dose, Safety, and Tolerability of Rhenium (186Re) in Pediatric Recurrent, Refractory or Progressive Ependymoma and High-Grade Glioma
Ependymoma · High Grade Gliomas
Not yet recruiting NCT07052877
The Effect of Glioblastoma PSMA Expression Following Tumour VEGF Blockade From Bevacizumab
Glioblastoma · Glioblastoma Multiforme (GBM)
Recruiting NCT06773481
BC008-1A Injection for Recurrent CNS WHO G4 Glioma
Glioma · Glioma Tumor Recurrence · Glioma, Recurrent High Grade
Recruiting NCT04266977
Restrictive Use of Dexamethasone in Glioblastoma
Glioblastoma · Dexamethasone · Steroids
Recruiting NCT06632860
A Dual-targeting Tracer TATE-RGD for the Diagnosis of SSTR- and RGD- Positive Tumors
Iodine-resistant Thyroid Cancer · Meningioma · NETs
Recruiting NCT06954636
Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study
Glioblastoma Multiforme, Adult · Glioblastoma or Gliosarcoma · Glioblastoma, Adult
Not yet recruiting NCT07020052
Phase II Exploratory Study of Sequential Triple Therapy (Temozolomide/Anlotinib/Bemarituzumab) in Combination With Concurrent Radiotherapy With Temozolomide and Anlotinib for the Maintenance Treatment of Diffuse Midline Gliomas in Children
Maintenance Treatment of Diffuse Midline Gliomas in Children
Recruiting NCT07049094
The Analgesic Effect of Scalp Nerve Block Using Bupivacaine Liposomes for Postoperative Pain Relief After Craniotomy
Brain Tumor Adult · Cerebrovascular Disease
Not yet recruiting NCT07047066
A Phase II Clinical Study to Evaluate the Efficacy and Safety of Flazoparib Combined With Temozolomide After the Completion of Standard Concurrent Chemoradiotherapy (CCRT) in Newly Diagnosed Glioblastoma
Glioblastoma
Recruiting NCT07044076
Translation and Validation of the MQOL Self-questionnaire Into French for Assessing Quality of Life in Patients With Meningiomas
Quality of Life · Meningioma
Recruiting NCT04765098
Tamoxifen Versus Etoposide After First Recurrence in GBM Patients
Glioblastoma Multiforme
Enrolling by invitation NCT06896110
Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma
Glioblastoma (GBM) · Diffuse Midline Glioma (DMG) · Astrocytoma, IDH-Mutant, Grade 4
Recruiting NCT05879367
Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma
Glioblastoma, IDH-wildtype · Glioblastoma · Glioblastoma Multiforme
Not yet recruiting NCT07036783
3D Decision Support Tool for Brain Tumour Surgery Development and Validation: Observational Study
Brain (Nervous System) Cancers · Brain Tumor, Primary
Recruiting NCT06036706
Neurocognitive Impact of Different Irradiation Modalities for Patients With Grade I-II Skull Base Meningioma:
Meningioma · Radiation Toxicity
Recruiting NCT04111588
Diagnostic Assessment of Amino Acid PET/MRI in the Evaluation of Glioma and Brain Metastases
Brain Neoplasms
Not yet recruiting NCT07029100
Feasibility of ORGAnoids in Routine Clinical Practice for Molecular Analysis of the GLIOvascular Niche in Patients With Primary Brain Tumors.
Glioblastoma
Recruiting NCT07021339
Anterior Temporal Lobectomy in Temporal Glioblastoma
Newly-diagnosed Glioblastoma · Temporal Lobe
Recruiting NCT06183983
Hitting the Mark: Introducing State-of-the-art MRI for Precision Radiotherapy of Glioblastoma
Glioblastoma
Recruiting NCT05702944
The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma
Pheochromocytoma · Paraganglioma · Adrenalectomy; Status
Recruiting NCT05831631
Characterization of Circulating and Tumor-infiltrating Immune Cells in Malignant Brain Tumors
Brain Tumor, Primary · Brain Tumor - Metastatic
Recruiting NCT05775458
Glutamate Excitotoxicity and Its Role in Glioblastoma Biology
Brain Tumor, Primary
Recruiting NCT06551909
Radioimmunotherapy in Solid Tumors (PNRR-MCNT2-2023-12378239-Aim2)
Glioblastoma
Recruiting NCT05226494
Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma
Glioma, Malignant
Not yet recruiting NCT07004075
FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration
Low-grade Glioma · Pediatric Low-grade Gliomas · pLGG With BRAF Alteration
Enrolling by invitation NCT06999148
Study on The Sensitizing Effect of Sonodynamic Therapy on The Treatment of Brainstem Glioma With Radiotherapy and Chemotherapy and Survival Analysis
Glioma (Any Grade) in the Brain
Recruiting NCT05564949
A Ketogenic Diet as a Complementary Treatment on Patients With High-grade Gliomas and Brain Metastases
Brain · Cancer
Not yet recruiting NCT01777919
Disulfiram/Copper Combination In The Treatment of Newly Diagnosed Glioblastoma Multiform
Glioblastoma Multiforme
Recruiting NCT05439278
Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly Glioblastoma
Glioblastoma
Recruiting NCT06975332
Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) Progression
Glioblastoma · High-Grade Gliomas · Grade III Astrocytoma
Recruiting NCT05474573
Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases
Glioma, Malignant · Metastases to Brain
Recruiting NCT05380349
Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma
Newly Diagnosed Glioblastoma
Recruiting NCT06381570
Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas
Low-grade Glioma
Recruiting NCT06160492
Phase III Clinical Trial Evaluating the Resection Efficacy of 5-Aminolevulinic Acid Hydrochloride (5-ALA HCl) Fluorescence-Guided Microsurgery Versus Conventional White Light Microsurgery in Patients With Malignant Glioma (WHO Grade 3/4)
5-aminolevulinic Acid · Fluorescence-guided Resection
Recruiting NCT04254419
Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells
High Grade Glioma
Recruiting NCT05397873
Biofeedback for Hemianopia Vision Rehabilitation
Hemianopsia, Homonymous · Brain Injury · Stroke
Recruiting NCT06959979
Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma
Medulloblastoma, Childhood
Recruiting NCT06598787
A Study of BL-B01D1 in Patients With Recurrent Glioblastoma
Recurrent Glioblastoma
Not yet recruiting NCT06869577
A Supportive Group Intervention for Caregivers to Patients Diagnosed With a Glioblastoma
Caregiver · Glioblastoma Multiform (Grade IV Astrocytoma)
Recruiting NCT05432518
Pilot Trial for Treatment of Recurrent Glioblastoma
Glioblastoma · Recurrent Disease · Recurrent Glioblastoma
Recruiting NCT06632236
5G-EMERALD: Amivantamab in Malignant Brain Tumours
Malignant Primary Gliomas · Glioblastoma Multiform (Grade IV Astrocytoma) · Diffuse Hemispheric Glioma, H3 G34-Mutant
Recruiting NCT06943742
Non-Helium Magnetoencephalography in Pediatric Brain Tumors
Pediatric Brain Tumor
Recruiting NCT06874426
The Impact of Endoscopic Endonasal Skull Base Surgery on Olfaction
Meningioma · Pituitary Disease · Pituitary Adenoma
Not yet recruiting NCT06939400
Photodynamic Therapy for Glioblastoma Multiforme Based on Metaverse and Yellow Fluorescence
Glioblastoma Multiforme (GBM)
Not yet recruiting NCT06750458
Dapagliflozin Versus Dexamethasone Role in Pre-operative Management of Non- Diabetic Brain Tumor Patients
Glioma · Dapagliflozin (Forxiga) · Dexamethasone
Not yet recruiting NCT06937268
DOTATATE PET for Meningioma Radiation Planning
Meningioma
Recruiting NCT06936046
Enhanced Adjuvant Therapy for Newly Diagnosed GBM With Partial Surgical Resection or Short-term Progression
Glioblastoma
Not yet recruiting NCT06929819
Research on the Safety and Efficacy of Intraoperative Radiation Therapy in Malignant Cerebral Tumor
Glioblastoma · Brain Tumor, Primary · Brain Tumor - Metastatic
Recruiting NCT04997317
Treatment of Recurrent or Progressive Meningiomas With the Radiolabelled Somatostatin Antagonist 177Lu-satoreotide
Meningioma
Recruiting NCT06924099
TTFields General Routine Clinical Care in ndGBM Patients: a French Prospective Non-Interventional Study (TIGER France)
Glioblastoma
Recruiting NCT06779487
Systemic Biomarkers to Predict Radiation-Induced Neurocognitive Decline
Brain Tumors · Medulloblastoma · Glioma
Recruiting NCT06381531
Tracing Brain Tumors Through Deep Time
Brain Tumor · Oncology
Recruiting NCT06016452
A Study of Chlorophyllin for the Management of Brain Radio-necrosis in Patients With Diffuse Glioma
Diffuse Glioma · Radionecrosis of Brain · High Grade Glioma
Recruiting NCT04250064
A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma
DIPG
Recruiting NCT04775485
A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
Low-grade Glioma · Advanced Solid Tumor
Recruiting NCT06922487
Assessment of Tiredness During Awake Resection of Intracerebral Tumors
Brain Tumor Adult · Awake Surgery
Recruiting NCT06922500
Processed EEG for Monitoring of Anesthetic Depth in Intracranial Tumor Surgery
Brain Tumor Adult · Processed EEG · Total Intravenous Anesthesia
Recruiting NCT06687681
Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas
Glioma Glioblastoma Multiforme · High Grade Glioma (III or IV)
Recruiting NCT06036381
Spatial and Temporal Characterization of Gliomas Using Radiomic Analysis
Glioma
Recruiting NCT04474964
Focal Radiotherapy Plus Low Dose Craniospinal Irradiation Followed by Adjuvant Chemotherapy in WNT Medulloblastoma.
Medulloblastoma, WNT-activated
Recruiting NCT06036394
Artificial Intelligence in CNS Radiation Oncology
CNS Tumor
Recruiting NCT06915649
Exploration and Evaluation of Amygdalo-Hippocampectomy According to Prof. Coubes' Technique: An Anatomical, Clinical, and Educational Approach
Hippocampal Sclerosis · Dysembryoplastic Neuroepithelial Tumor · Cortical Dysplasia
Recruiting NCT05495295
First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Advanced Solid Tumours
Malignant Tumor · Advanced Solid Tumor · Glioblastoma Multiforme
Not yet recruiting NCT06914427
PET/CT Imaging Study With Simultaneous Dual-nuclide Imaging Technique
Prostatic Neoplasms · Glioma · PARKINSON DISEASE (Disorder)
Recruiting NCT06282562
FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients
Brain Tumor, Primary · Exercise
Recruiting NCT06899516
Project MILANO: Connections Between Patients With Brain Tumors and Their Pets: an Analysis of Concerns and Needs
Brain (Nervous System) Cancers
Recruiting NCT06306118
Autoguide Positioning Device for Multiple Stereotactic Biopsies
Multiple Stereotactic Tumor Biopsies During a Brain Tumor Resection
Recruiting NCT03849430
Longitudinal Analysis of the Health-related Quality of Life in Glioma Patients
Glioma of Brain
Not yet recruiting NCT06749925
Clinical Trial Assessing the Efficacy and Safety of Dendritic Cell-Based Immunotherapy for Glioblastoma
Glioblastoma