Recruiting NCT05083754
Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma
Glioblastoma Multiforme
CNS tumors
876 trials in this section
Recruiting NCT07240662
Vorasidenib in CNS WHO Grade 2 IDH-mutant Diffuse Glioma
Glioma
Not yet recruiting NCT07331064
Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor
High Grade Gliomas · Atypical Teratoid Rhabdoid Tumors (ATRT) · Diffuse Midline Glioma
Recruiting NCT07323966
Feasibility of Mask-Free Radiotherapy for Brain Tumor Patients
Brain Tumor
Recruiting NCT06558214
OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd Trial
Recurrent Glioblastoma
Recruiting NCT02358187
A Vaccine Trial for Low Grade Gliomas
Low Grade Glioma
Recruiting NCT07321353
Survivors Journey+
Pediatric Brain Tumor
Enrolling by invitation NCT07316075
Multicenter Study on Cardiovascular and Metabolic Complications in Patients With Biochemically Silent Pheochromocytomas and Paragangliomas
Cardiovascular Abnormalities · Arterial Blood Pressure · Heart Rate
Recruiting NCT05049148
Platelets Activation in Brain Neoplasms
Glioma · Blood Platelets · Inflammation
Recruiting NCT07093814
A Study of VRT106 for Injection in Patients With Recurrent/Progressive Glioblastoma
Glioblastoma
Recruiting NCT06829173
Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas
High-Grade Glioma
Recruiting NCT07306299
A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma
Glioma, High Grade
Recruiting NCT05423210
Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme
Glioblastoma Multiforme
Recruiting NCT07145047
Clinical Study of Oncolytic Virus in Glioblastoma
Glioblastoma (GBM)
Recruiting NCT06468176
Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma
Glioma, Malignant
Not yet recruiting NCT07291102
Comparison of Neurocognitive Outcome in Two Standard Regimen for Treatment of Low-risk Medulloblastoma
Medulloblastoma
Recruiting NCT04543201
Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade Glioma
Glioma
Recruiting NCT05259605
Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification
Glioma · Glioneuronal Tumor · Choroid Plexus Tumor
Recruiting NCT07288931
Al18F-NOTA-LM3 PET/CT in Patients With Pheochromocytoma and Paraganglioma
Pheochromocytoma/Paraganglioma (PPGL)
Recruiting NCT05976490
NeuroPathways Intervention for Brain Tumor Patients
Malignant Brain Tumor · Glioma · Coping Skills
Recruiting NCT05686798
Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.
Malignant Glioma of Brain · Astrocytoma · Malignant Astrocytoma
Not yet recruiting NCT07264023
Correlation Between Nutritional Status of Childhood Neurological Tumors and Quality of Life
Nutritional Status · Quality of Life · Children
Not yet recruiting NCT07286396
Non-invasive Intracranial Pressure Monitoring in Brain Tumor Patients
Brain Neoplasm · Intracranial Pressure Increase
Recruiting NCT06898684
Medulloblastoma Online Video-based Exercise Pilot Study
Medulloblastoma, Childhood
Recruiting NCT07286929
Evaluation of the Variation Over Time of Visuospatial Deficit in Patients With Parietal Lobe Glioma
Glioma · Parietal Lobe Glioma · Visuspatial Deficit
Recruiting NCT07286903
Fluorescence Enhanced Stereotactic Surgery (FESS)
High Grade Glioma · High Grade Glioma (III or IV)
Not yet recruiting NCT07286292
Vorasidenib Study in Pediatric Participants With Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation
Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation
Recruiting NCT03761121
Developing Fast Pediatric Imaging
Pediatric Low-grade Gliomas
Recruiting NCT07077616
Clinical Study for the Safety and Therapeutic Efficacy of the AI-QMMM Designed TamavaqTM Personalised Vaccine in Patients With Newly Diagnosed Glioma.
Glioma
Recruiting NCT02417324
International HIT-MED Registry (I-HIT-MED)
Childhood Brain Tumor
Recruiting NCT07263711
Prospective Real-World Study of Pathology AI for Glioma Molecular Prediction
Glioma
Recruiting NCT05553041
18F-Fluciclovine PET-MRI in High-grade Glioma
Glioma · High Grade Glioma · Glioma, Malignant
Recruiting NCT05990244
Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion
Glioma
Recruiting NCT06964815
Silibinin in Association With Concomitant Chemoradiotherapy and Maintenance Temozolomide in STAT3 Positive IDH Wild-type, Newly Diagnosed Glioblastoma Patients
Glioblastoma · IDH Wild-type and STAT3-positive Glioblastoma
Not yet recruiting NCT07254845
A PROSPECTIVE, SINGLE-CENTERED, ASSESSOR-BLINDED STUDY TO EVALUATE THE CLINICAL EFFICACY OF THE PROPOSED CELL/TISSUE HISTOPATHOLOGY PROCESSOR CCELL (CONFOCAL FLUORESCENCE ENDOMICROSCOPY) FOR INTRAOPERATIVE DIAGNOSIS IN BRAIN TUMORS
Frozen Sections · Indocyanine Green (ICG) · Brain Tumor
Recruiting NCT06613841
Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma
Glioblastoma · Recurrent Glioblastoma · Glioblastoma Multiforme of Brain
Recruiting NCT05770544
DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.
Haematological Malignancy · Malignancy · Malignant Neoplasm
Recruiting NCT04081701
68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.
CNS Tumors · Meningioma · Esthesioneuroblastoma
Recruiting NCT06930846
HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)
Brain Cancer · Brain Tumor · Brain Neoplasms
Recruiting NCT05052957
hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM)
Glioblastoma Multiforme · Glioblastoma Multiforme, Adult · Supratentorial Glioblastoma
Recruiting NCT02914067
Cognitive Biomarkers in Pediatric Brain Tumor Patients
Childhood Brain Tumor
Recruiting NCT04945148
Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide
Glioblastoma, IDH-wildtype
Not yet recruiting NCT07243340
A Phase I/IIa Study of C5252 in Patients With Intracranial Tumor
Glioma, Malignant
Recruiting NCT04299191
Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
High-grade Glioma · Solid Tumor, Unspecified, Child
Not yet recruiting NCT07164053
Evaluation of Image Quality and Safety of the MyVeo Surgical Visualization Headset During Standard Neurosurgical and Reconstructive Procedures Using Compatible Microscopes.
High-Grade Glioma (WHO III-IV) · Cerebral Vascular Conditions Requiring Surgical Intervention · Conditions Requiring Plastic and Reconstructive Surgery
Recruiting NCT06072586
A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions
High Grade Glioma · Glioblastoma
Recruiting NCT05480644
Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors
Brain Tumor, Primary · Brain Metastases, Adult
Not yet recruiting NCT07211841
Correlative Analysis Between Magnetic Resonance Spectroscopy (MRS) and Essential Clinicobiological Data in Glioblatoma Multiforme (GBM)
Glioblastoma · MRI Spectroscopy · Tumor Microenvironment
Recruiting NCT07111182
Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery
Brain Neoplasms
Recruiting NCT02977780
INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Glioblastoma
Recruiting NCT06090903
Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma
Glioblastoma · Recurrent Glioblastoma · Resectable Glioblastoma
Recruiting NCT07225101
Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures
Wound Closure · Brain Tumor Adult · Spine
Recruiting NCT07129317
Pediatric Radiation Therapy Registry
Sarcoma · Pediatric Brain Tumors
Recruiting NCT05717153
Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma
Diffuse Glioma · Malignant Glioma
Recruiting NCT06455605
D2C7-IT + 2141-V11 Combination Post-resection in rGBM
Recurrent Glioblastoma IDH Wildtype
Not yet recruiting NCT04373785
NG101m Adjuvant Therapy in Glioblastoma Patients
Glioblastoma Multiforme
Not yet recruiting NCT07219199
Residual IDH1-Mutant Tumor Cell Quantification Study
Glioma
Recruiting NCT03101813
International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository
Diffuse Intrinsic Pontine Glioma · Diffuse Midline Glioma, H3 K27M-Mutant · Diffuse Midline Glioma
Recruiting NCT03160274
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions
Pheochromocytoma · Paraganglioma · Inherited Cancer Syndrome
Recruiting NCT00870129
Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors
Brain Cancer · Glioma
Recruiting NCT07145112
Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma
Glioblastoma
Recruiting NCT06059690
Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells
Glioblastoma Multiforme · Glycolytic Index · Epidermal Growth Factor Receptor
Not yet recruiting NCT07211360
Integrated PET/MR Imaging With Amino Acid Radiotracers in the Evaluation of Brain Neoplasms: Assessing Diagnostic Accuracy and Therapeutic Response
Primary and Secondary Brain Tumors
Recruiting NCT05734560
D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients
Newly Diagnosed MGMT Unmethylated Glioblastoma
Not yet recruiting NCT07197086
Clinical and Treatment Determinant of Prognosis in Glioblastoma
Glioblastoma
Recruiting NCT04794972
A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors
Recurrent Glioma · Solid Tumor
Recruiting NCT05895344
Long-term Cognitive and Functional Impact of Proton-therapy or Modern Fractionated Radiotherapy in Cavernous Sinus Meningioma: An Open-label Randomized 1:1 Phase III Study
Cavernous Sinus Meningioma · Proton-therapy · Photon Radiotherapy
Recruiting NCT02509442
Measure of the Potential Evoked by Electric Stimulation
Low Grade Glioma of Brain
Recruiting NCT05310448
Tumor Treating Fields for the Treatment of Brainstem Gliomas
Glioma
Recruiting NCT07195500
Clinical Application of Somatostatin Receptor and Norepinephrine Transporter Targeted Imaging for Diagnosis and Staging of Neuroblastoma and Pheochromocytoma/Paraganglioma
Neuroblastoma · Pheochromocytoma · Paraganglioma
Recruiting NCT07193654
Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced Spread
Glioblastoma (GBM)
Recruiting NCT05532397
Evaluation of ex Vivo Drug Combination Optimization Platform in Recurrent High Grade Astrocytic Glioma
Glioma, Astrocytic
Recruiting NCT04772456
Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas
Glioma
Not yet recruiting NCT02864888
Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma
Brain Stem Glioma
Enrolling by invitation NCT07182175
Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors
Primary Aldosteronism · Adrenal Tumor · Cushing s Syndrome
Recruiting NCT05340881
Systematic Light Exposure in Pediatric Brain Tumor Survivors
Brain Tumor
Recruiting NCT06835803
Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial
Glioblastoma (GBM)
Recruiting NCT07179328
Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy
GBM · Glioblastoma Multiforme (GBM) · Glioblastoma Multiforme of Brain
Not yet recruiting NCT02887040
Study of Antineoplaston Therapy + Radiation vs. Radiation Only in Diffuse, Intrinsic, Brainstem Glioma
Brain Stem Glioma
Recruiting NCT06831461
Proton Versus Photon Radiotherapy in Adults With Primary Brain Tumors
Primary Brain Tumors · Diffuse Glioma · Meningioma
Recruiting NCT07141732
Combined Treatment of Patients With Newly Diagnosed Glioblastoma Using the Xoft® Axxent® Electronic Brachytherapy (eBx®) System for Intraoperative Balloon Electronic Brachytherapy
Glioblastoma
Not yet recruiting NCT06492486
Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow
Diffuse Glioma · Glioblastoma · Adaptive Radiotherapy
Enrolling by invitation NCT05014841
The Neural Coding of Speech Across Human Languages
Epilepsy · Brain Tumor · Speech
Not yet recruiting NCT07172178
γδ T-PD-1 Ab Cells in the Treatment of Malignant Meningioma
Malignant Meningioma
Recruiting NCT05386043
Registering Genomics and Imaging of Tumors (ReGIT)
Glioma
Recruiting NCT06552260
A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma
Glioblastoma · Recurrent Glioblastoma · Brain Tumor
Not yet recruiting NCT07162324
A Multicenter, Prospective Study for Glioblastoma Patients
Glioblastoma
Recruiting NCT06989086
FearLess in NeuroOncology
Primary Malignant Brain Tumor · Glioblastoma (GBM) · Astrocytoma
Recruiting NCT07162246
Combined Gamma Knife/Linac Radiosurgery for Large Brain Tumors / Metastases
Brain (Nervous System) Cancers · Brain Metastasases · SRS
Not yet recruiting NCT07021573
Protoporphyrin Imaging in Multispectral Evaluation of Resections
Glioma
Recruiting NCT05622409
A Taiwanese Oncogenetic Panel and Integrated Clinical Data Registry Study for Diffuse Glioma
Primary Malignant Brain Tumors
Recruiting NCT07158710
Phase I Study of HSK42360 in Malignant Brain Tumors With BRAF V600 Mutation
Malignant Brain Tumors
Recruiting NCT07159607
Amino Acid PET-based Response Assessment in IDH-mutant Gliomas (APPEAR)
IDH-mutant Glioma (Oligodendroglioma, Astrocytoma)
Recruiting NCT06102525
A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 With Valganciclovir (VGCV) in Subjects With Glioblastoma
Glioblastoma
Recruiting NCT04977375
Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
Glioblastoma Multiforme
Recruiting NCT06309251
Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients
Drug Resistant Epilepsy · Autism Spectrum Disorder · Chronic Migraine
Recruiting NCT05978557
Brain Slice Explants to Predict Drug Response in Brain Tumors
Central Nervous System Tumor
Recruiting NCT06519682
A Pilot Study Investigating Upfront Adaptive Immunotherapy Approach in Children, Adolescent and Young Adult (CAYA) Patients With Replication-Repair Deficient (RRD) High-Grade Gliomas (HGG)
High Grade Glioma · Replication Repair Deficient
Recruiting NCT07144735
Allogeneic γδT Cells in Glioblastoma
Glioblastoma (GBM) · Glioblastoma Multiforme (GBM)
Recruiting NCT06173076
A Prospective Study to Evaluate Clinical Outcomes in Anti-LGI1 Encephalitis
Autoimmune Encephalitis · Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis