Recruiting NCT05459870
CAR-T Cells Targeting Autoimmune Diseases
Autoimmune Diseases
CAR-T & cell therapy
1,352 trials in this section
Recruiting NCT04010877
Multiple CAR-T Cell Therapy Targeting AML
Acute Myeloid Leukemia
Recruiting NCT04429451
PSMA-specific CAR-T Cell Therapy
PSMA Positive Tumors or Tumor Tissues
Recruiting NCT05436496
CD19/70 Bi-specific CAR-T Cell Therapy
B Cell Malignancies
Recruiting NCT03271632
Multi-CAR T Cell Therapy in the Treatment of Multiple Myeloma
Multiple Myeloma
Recruiting NCT03125577
Combination CAR-T Cell Therapy Targeting Hematological Malignancies
B-cell Malignancies
Recruiting NCT05432882
CD19/22 Bi-specific CAR-T Cell Therapy
B Cell Malignancies
Recruiting NCT05995041
Universal CAR-T Cells Targeting AML
Acute Myeloid Leukemia
Recruiting NCT06006741
Universal CAR-T Cells Targeting Multiple Myeloma
Multiple Myeloma in Remission
Recruiting NCT07564401
A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy
Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Not yet recruiting NCT07663422
Mycophenolate Mofetil w/ Prednisone for Immune Related Hepatitis From Checkpoint Inhibitor Therapy
Immune-mediated Hepatitis · Immune-related Adverse Event
Recruiting NCT05437315
GD2/PSMA Bi-specific CAR-T Cell Therapy
Solid Tumor
Recruiting NCT04427449
4SCAR-CD44v6 T Cell Therapy Targeting Cancer
Cancers Which Are CD44v6 Positive
Not yet recruiting NCT06992934
Immunological Impact of a Post Cell Therapy Treatment With FLT3 Inhibitors
Hematological Malignancies
Not yet recruiting NCT07657481
Comparison of the Effects of Two Different Exercise Programs on Femoral Cartilage Thickness and Clinical Parameters in Individuals With Knee Osteoarthritis
Osteo Arthritis of the Knee
Recruiting NCT04290000
Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies
Lymphoma and Acute Lymphoblastic Leukemia
Not yet recruiting NCT07659704
CD19-Directed CAR-T Cell Therapy in Refractory Systemic Lupus Erythematosus
Lupus Erythematosus, Systemic
Enrolling by invitation NCT06518668
A Study of NKX019, a CD19 CAR NK Cell Therapy, in Subjects With Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
Recruiting NCT07255664
A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC
Metastatic Colorectal Cancer · Prostate Cancer Metastatic · Prostate Cancer Locally Advanced
Recruiting NCT06352242
Is Trogocytosis a Predictive Marker of CAR-T Cell Response in Diffuse Large B-cell Lymphoma?
Diffuse Large B Cell Lymphoma
Recruiting NCT04637503
4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating Neuroblastoma
Neuroblastoma
Recruiting NCT06017258
A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia · Relapsed Acute Myeloid Leukemia · Acute Myeloid Leukemia
Recruiting NCT07493395
Phase IIa Trial of Anti-CD19 CAR T-Cells in Systemic Sclerosis Resistant to Immunosuppressive Therapy
Scleroderma, Systemic
Recruiting NCT07645690
The Safety and Efficacy of Allogeneic CD70 CAR-T Therapy in Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
Recruiting NCT07328503
CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia · B-All
Recruiting NCT04545762
Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma
Refractory Non-Hodgkin Lymphoma · Burkitt Lymphoma · Mantle Cell Lymphoma
Recruiting NCT06579469
Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy
B-ALL · Hematologic Malignancy · Solid Tumor
Not yet recruiting NCT07657585
CIB In Vivo CAR-T Lentiviral Injection in Patients With Advanced Malignant Tumors
Advanced Malignant Solid Tumors
Not yet recruiting NCT07657871
Comparison of Minced Cartilage Implantation Versus Microfracture for Acetabular Chondral Lesions Due to FAI (Femoro-acetabular Impingement)
Femoro-acetabular Impingement (FAI)
Recruiting NCT07116057
MOv19-BBz CAR T Cells in FRa+ Cancers
Metastatic Non Small Cell Lung Cancer · Recurrent Lung Non-Small Cell Carcinoma
Recruiting NCT07656649
Effect of a Liberal Fasting Regime (Sip-til-Send) on Preoperative Gastric Volume Measured Using Point of Care Ultrasound
Fasting Status
Recruiting NCT06138587
Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation
Acute Myeloid Leukemia · Leukemia · Leukemia, Myeloid
Recruiting NCT07074496
Efficacy, Safety, and Pharmacokinetics of ThisCART19A Combined With Olverembatinib in Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia.
Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Not yet recruiting NCT07651618
A Phase II Trial of Tumour Infiltrating Lymphocyte Adoptive Cell Therapy in Patients With Immune Checkpoint Inhibitor Resistant Unresectable or Metastatic Melanoma
Melanoma (Skin Cancer) · Melanoma Metastatic
Recruiting NCT06839976
CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus
SLE · Systemic Lupus Erythematosus (SLE) · CAR T Cell
Recruiting NCT06749366
Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing
Enchondromatosis
Recruiting NCT07575919
Targeted CD22/CD19 CAR-T Therapy for Consolidation in Standard-Risk B-ALL
B-cell Acute Lymphoblastic Leukemia
Recruiting NCT06213311
A Study of Axicabtagene Ciloleucel and Glofitamab as Second-Line Therapy for Relapsed or Refractory Patients With Large B Cell Lymphoma
B Cell Lymphoma
Recruiting NCT06703892
A Study to Evaluate the Safety and Clinical Activity of GF- CART01 (CD20/19 CAR T Cell) in Subjects With Relapsed or Refractory B-Cell Hematological Malignancies
Diffuse Large B Cell Lymphoma Relapsed · Diffuse Large B Cell Lymphoma Refractory · Follicular Lymphoma ( FL)
Recruiting NCT05686226
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
Cervical Cancer · Throat Cancer · Oropharynx Cancer
Recruiting NCT07544992
Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas
Recurrent Astrocytoma, IDH-Mutant, Grade 4 · Recurrent Glioblastoma, IDH-Wildtype
Recruiting NCT06549231
Evaluation of Efficacy and Safety of Rituximab and Mycophenolate Mofetil Combination in Patients With Interstitial Lung Disease Related to Systemic Sclerosis
Interstitial Lung Disease With Systemic Sclerosis
Recruiting NCT06051695
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Solid Tumor, Adult · Colorectal Cancer · NSCLC
Recruiting NCT05483491
KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer
Gastric Cancer · Breast Cancer · Cervical Cancer
Recruiting NCT07641036
Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer
Cholangiocarcinoma · Intrahepatic Cholangiocarcinoma · Extrahepatic Cholangiocarcinoma
Not yet recruiting NCT07643155
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
Hepatic Impairment
Recruiting NCT06163573
Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage.
Patellofemoral Osteoarthritis
Not yet recruiting NCT07335328
Fully Human Bispecific Anti-CD20, Anti-CD19 CAR T Cells for Patients With Relapsed and/or Refractory B Cell Malignancies
B-cell Non Hodgkin Lymphoma
Recruiting NCT05436418
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
Peripheral Blood Stem Cell Transplantation · Hematopoietic Stem Cell Transplantation
Enrolling by invitation NCT06985576
Long-term Study to Evaluate Safety and Persistence of GF-CART01
DLBCL - Diffuse Large B Cell Lymphoma · Follicular Lymphoma (FL) · Primary Mediastinal Large B-Cell Lymphoma
Recruiting NCT05588453
Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain
Clinical Stage IV Cutaneous Melanoma AJCC v8 · Metastatic Malignant Neoplasm in the Brain · Metastatic Melanoma
Recruiting NCT02821806
Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy People for the Expansion of T Cells for Adoptive Cell Therapy
Healthy Volunteer
Not yet recruiting NCT07641868
Management of Focal Cartilage Lesions of the Knee: The Benefits of an Autograft Procedure
Focal Cartilage Lesions of the Knee
Recruiting NCT07641049
Dual-target PSMA/PSCA CAR-NK Cells in Advanced Prostate Cancer
Metastatic Castration-resistant Prostate Cancer · Advanced Prostate Adenocarcinoma · PSCA-positive Prostate Cancer
Recruiting NCT07641023
Dual-Target CAR-NK Cells Targeting MSLN, EGFR, or HER2 in Advanced NSCLC
Non-Small Cell Lung Cancer · Advanced/Metastatic
Recruiting NCT04844866
Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients
Diffuse Large B-cell Lymphoma
Recruiting NCT07481981
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
Pulmonary Arterial Hypertension
Recruiting NCT07640230
Effects of Cartoons and Mobile Games on Preoperative Anxiety and Fear in Children With Appendicitis: An RCT
Preoperative Anxiety · Children · Appendicitis (Diagnosis)
Enrolling by invitation NCT07638579
Comparison of Intraoperative Neuromonitoring With Transcartilaginous Needle Electrodes Versus Endotracheal Tube Electrodes in Thyroid and Parathyroid Surgery
Thyroid Surgeries · Parathyroidectomy
Not yet recruiting NCT06681376
Enhancing the Emergency Department Experience for Older Adults: Study Protocol for the Implementation of a Comfort Menu and Cart
Emergency Department Patient · Comfort
Recruiting NCT02917083
CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)
Hodgkin's Lymphoma · Non-Hodgkin Lymphoma
Not yet recruiting NCT07638982
Axatilimab + CAR-T for High-Risk Lymphoma
Diffuse Large B Cell Lymphoma (DLBCL) · Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma · High-grade B-cell Lymphoma (HGBCL)
Recruiting NCT04892277
CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies
Recurrent B-Cell Non-Hodgkin Lymphoma · Recurrent Chronic Lymphocytic Leukemia · Recurrent Small Lymphocytic Lymphoma
Recruiting NCT07519187
CAR 70-BCMA CAR-T Cells for the Treatment of Relapsed or Refractory Plasma Cell Neoplasms
Relapsed or Refractory Plasma Cell Neoplasms
Not yet recruiting NCT07491367
Pilot Exploration of Platelet Characterization of Platelet Rich Plasma Created by Two Different Systems
Knee Osteoarthristis · Cartilage Damage · Platelet Rich Plasma
Recruiting NCT05135091
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
Mesial Temporal Lobe Epilepsy
Not yet recruiting NCT07490275
Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases
Refractory/Relapsed Systemic Lupus Erythematosus · Refractory / Relapsed / Progressive Systemic Sclerosis · Refractory / Relapsing / Progressive Inflammatory Myopathy
Recruiting NCT04864054
GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC
Hepatocellular Carcinoma · Liver Cancer, Adult · Liver Neoplasm
Recruiting NCT06167785
A Study to Evaluate Zanubrutinib and Tislelizumab in Progressive Lymphoma Post CAR-T
Large B-cell Lymphoma
Recruiting NCT05963217
Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL
Relapsed or Refractory CD19+ B-cell Lymphoma · Relapsed or Refractory Chronic Lymphocytic Leukemia · Relapsed or Refractory Small Lymphocytic Lymphoma
Recruiting NCT07635875
Scar Remodeling After Burn Injury Using Allogeneic Adipose-derived Stromal Cells
Scar Conditions and Fibrosis of Skin · Scar Quality Assessment and Safety · Scar Tissue
Recruiting NCT02621021
A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab
Melanoma
Recruiting NCT07200102
Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma
Multiple Myeloma
Recruiting NCT07145450
Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC
PDAC
Recruiting NCT06158139
Autologous CAR-T Cells Targeting B7-H3 in PDAC
Pancreas Cancer · Relapse · Resistant Cancer
Not yet recruiting NCT07633795
Effect of TECAR Therapy on Pain, Balance, and Quality of Life in Elderly Men With Knee Osteoarthritis
Knee Osteoarthritis
Recruiting NCT06643221
Exercise as an Immune Adjuvant for Allogeneic Cell Therapies
Leukemia · Hematopoetic Stem Cell Transplantation · Donor Lymphocyte Infusion
Recruiting NCT07285694
AB-3028, a Programmable Circuit T Cell Therapy in Patients With Castration Resistant Prostate Cancer (CRPC)
Metastatic Castration Resistant Prostate Cancer (mCRPC)
Recruiting NCT07137494
A Study of MB-CART19.1 Cellular Therapy for People With Central Nervous System Lymphoma (CNSL)
Primary Central Nervous System (CNS) Lymphoma · Secondary Central Nervous System Lymphoma
Recruiting NCT07606937
A Study of Automated Axicabtagene Ciloleucel for R/R Large B-cell Lymphoma.
Relapsed/Refractory Large B-cell Lymphoma
Recruiting NCT07629596
Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of Arnovie101, an mRNA-LNP-Based In Vivo CAR-T Therapy, for the Treatment of B Cell-Mediated Autoimmune Diseases (SLE and AIHA)
Systemic Lupus Erythematosus · Autoimmune Hemolytic Anemia (AIHA)
Recruiting NCT06271057
Golcadomide Post-CAR T-cell in R/R Aggressive Large B-cell Lymphoma Patients With High Risk of Relapse
Diffuse Large B-cell Lymphoma Refractory · Refractory Primary Mediastinal Large B-Cell Lymphoma · Refractory Transformed B-cell Non-Hodgkin Lymphoma
Recruiting NCT03378102
Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation
Allogeneic Hematopoietic Stem Cell Transplantation
Recruiting NCT07627698
Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma
Unresectable Melanoma · Metastatic Cutaneous Melanoma · Metastatic Uveal Melanoma
Recruiting NCT07626879
Feasibility and Effectiveness of a Ring-Type Blood Pressure Device (CART-BP) Compared With 24-Hour Ambulatory Blood Pressure Monitoring in HFrEF
Heart Failure With Reduced Ejection Fraction; Hypertension
Recruiting NCT07627711
Dual-Target CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma (PDAC) · Unresectable Locally Advanced · Metastatic Disease
Recruiting NCT07626476
Autologous BCMA-targeted CAR-T Cell Injection for Relapsed/Refractory Light Chain Amyloidosis
Relapsed/Refractory Light Chain Amyloidosis · AL Amyloidosis · Systemic Light Chain Amyloidosis
Not yet recruiting NCT07443137
CAR-T ceLL for Eradication of Active Residual Disease in LBCL (CLEAR-1 Study)
Large-cell Lymphoma
Recruiting NCT06581198
A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)
Lupus Erythematosus, Systemic · Lupus Nephritis
Recruiting NCT05625594
Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/Mem T-lymphocytes) for the Treatment of Central Nervous System Lymphoma
Central Nervous System Lymphoma
Not yet recruiting NCT07623655
CAR-T Treatment in Pediatric and Adult Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia · B-Cell Acute Lymphoblastic Leukaemia
Not yet recruiting NCT07622784
Pirtobrutinib Maintenance After CAR-T Therapy in Relapsed or Refractory B-Cell Lymphoma
Relapsed or Refractory B-cell Lymphoma
Recruiting NCT07622940
Dual-Target CLDN18.2/HER2 CAR-NK Cells for Advanced Esophageal Adenocarcinoma
Recurrent or Metastatic Esophageal Adenocarcinoma · Biomarker-selected CLDN18.2-positive and/or HER2-positive Disease
Not yet recruiting NCT07619950
EVERolimus and LenvAtinib Versus Everolimus for Bone Sarcoma
Neoplasms of Bone and Articular Cartilage With Unspecified Anatomical Site
Not yet recruiting NCT07621471
IL-15 Enhanced NK Cell Therapy for Solid Tumors
Solid Tumors · Metastatic Cancer
Recruiting NCT04981119
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
Solid Tumor, Adult · Colorectal Cancer · Non Small Cell Lung Cancer
Recruiting NCT07617805
EGFR/HER2 Dual-Target CAR-NK Cells for Recurrent or Metastatic HNSCC
Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma · Biomarker-positive EGFR/HER2- Expressing HNSCC
Not yet recruiting NCT07608874
Comparing Decidual Inclusion vs. Exclusion in Uterine Suture Techniques During Cesarean Section to Improve Scar Thickness and Reduce Isthmocele Risk in Primiparous Women
Isthmocele · Cesarean Scar Diverticula
Recruiting NCT07617285
Allogeneic CAR-T(CT0890B) in NKG2DL+ R/R AML
AML · Refractory/Relapse Acute Myeloid Leukemia
Recruiting NCT07617753
Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16) pt2
Epithelial Ovarian Cancer · Primary Peritoneal Carcinoma · Fallopian Tube Carcinoma