Набор скоро начнётся NCT06708455
Phase 2b of RAPA-201 Cell Therapy in Post-PD-(L)-1 Melanoma
Malignant Melanoma With Metastasis · Malignant Melanoma · Malignant Melanoma Stage IIIc
CAR-T и клеточная терапия
1 352 исследования в этом разделе
Набор скоро начнётся NCT07481721
IL13Rα2 CAR-T Cells Secreting Anti-PD-L1 Antibody for Recurrent Malignant Glioma
Recurrent Malignant Glioma
Набор скоро начнётся NCT07479043
To Evaluate the Safety and Potential Therapeutic Activity of JadiCell™, an Investigational Umbilical Cord-Derived Mesenchymal Stem Cell Therapy, in Patients Diagnosed With Acute Respiratory Distress Syndrome (ARDS).
Acute Respiratory Distress Syndrome
Идёт набор NCT05538208
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
Lupus Nephritis
Идёт набор NCT07480954
Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16)
Epithelial Ovarian Cancer · Primary Peritoneal Carcinoma · Fallopian Tube Carcinoma
Идёт набор NCT07480928
Dual-Targeting CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma (PDAC) · Unresectable Locally Advanced or Metastatic Disease
Идёт набор NCT07479927
Telematic Cognitive Training and Mindfulness in Pediatric Patients After CAR-T Cell Therapy, Single Hematopoietic Allogeneic Transplant or Chemotherapy
Acute Lymphoblastic Leukemia
Идёт набор NCT07480213
Adaptive Phase 1/2 Study of Dual-Target CAR-NK Cells in Relapsed/Refractory Small Cell Lung Cancer (SCLC)
Small Cell Lung Cancer (SCLC) · Relapsed/Refractory SCLC · SCLC, Extensive Stage
Идёт набор NCT07480941
Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
Glioblastoma · High-grade Glioma · Malignant Glioma
Набор скоро начнётся NCT07476027
Efficacy and Safety of CD7 CAR-T in Newly Diagnosed High-Risk T-LBL/ALL
T Lymphoblastic Lymphoma · T Acute Lymphoblastic Leukemia
Идёт набор NCT07477912
Anti BCMA CAR- T Cell Therapy for Adults With Relapsed or Refractory Multiple Myeloma
Multiple Myeloma Refractory
Идёт набор NCT07164560
Exploratory Study of Umbilical Cord Blood-Derived CAR-NK Cell Therapy Targeting TRBC1/2 for Relapsed/Refractory T-Cell Lymphoma
Refractory/Recurrent Peripheral T-cell Lymphoma
Идёт набор NCT05024175
Long-term Follow-up of Subjects Treated With CAR T Cells
Long Term Adverse Effects · CAR-T · Duty to Follow Up
Идёт набор NCT06026319
CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma
Non-hodgkin Lymphoma · Relapsed Non-Hodgkin Lymphoma · Refractory Non-Hodgkin Lymphoma
Идёт набор NCT07475182
Exploratory Clinical Study of Targeted Activated DC and CAR-T Therapy in Advanced Solid Cancers
Advanced Solid Cancers
Идёт набор NCT06431347
Prospective Observational Cohort Study of Transplant and Cell Therapy Candidates and Recipients to Assess Social Determinants of Health
Transplant and Cell Therapy
Набор по приглашению NCT07474051
Long-Term Follow-Up of AvenCell Sponsored CAR-T Cell Clinical Trials
B-cell Lymphoma · Chronic Lymphocytic Leukemia · Hematologic Malignancy
Идёт набор NCT07472972
Dynamic Individualized Risk Profiling of Patients With Relapsed/Refractory Lymphoid Malignancies and CD19-CAR T Cell Therapy (INTeRCePT 2.0)
Lymphoma · Lymphoid Hematological Malignancies
Идёт набор NCT06711146
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Moderate to Severe Active SLE Clinical Research
Systemic Lupus Erythematosus
Идёт набор NCT07470073
A Clinical Study Exploring the Safety, Efficacy and Cell Metabolic Kinetics of Universal Car-t Cell Injection in CD19 and / or CD20 Positive Relapsed / Refractory B-cell Acute Lymphoblastic Leukemia in Adolescents, Children and Adults
ALL (Acute B-Lymphoblastic Leukemia)
Идёт набор NCT07462364
The Effect of a Kaleidoscope and Cartoons for Dental Treatment in Children
Dental Anxiety · Dental Fear · Pain
Набор скоро начнётся NCT07463781
Neurocognitive Assessment in Adults Undergoing CD19 Targeted CAR-T Cell Therapy
Diffuse Large B Cell Lymphoma (DLBCL) · High Grade B Cell Lymphoma · Primary Mediastinal B-cell Lymphoma (PMBCL)
Идёт набор NCT07471789
Safety and Efficacy of GYA01 (CART84) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) and Acute Lymphoblastic T Leukemia Patients (T-ALL).
Acute Myeloblastic Leukaemia · Leukemia, T-Cell
Набор скоро начнётся NCT07471191
Partial Thickness vs Full Thickness Tragal Cartilage Grafts in Endoscopic Type 1 Tympanoplasty
Tympanoplasty Surgery
Идёт набор NCT06875063
GB5005 CART-cell Injection in the Treatment of Patients With CD19-positive RR B-NHL
Non-hodgkin Lymphoma · Refractory Lymphoma · Chimeric Antigen Receptor T-cell
Идёт набор NCT07340463
The Efficacy and Safety of Biologics (Belimumab/ Telitacicept) Induction Therapy in Proliferative Lupus Nephritis Patients for 6 Months Compared With Mycophenolate Mofetil Treatment
Systemic Lupus Erythematosus (SLE) · Lupus Nephritis (LN)
Идёт набор NCT05141058
T Cell Therapy Opposing Novel COVID-19 Infection in Immunocompromised Patients
SARS-CoV-2 Infection
Набор скоро начнётся NCT05651997
Study Comparing Two Methods for the Treatment of Large Chondral and Osteochondral Defects of the Knee
Articular Cartilage Defect · Chondral Defect · Osteochondritis
Идёт набор NCT07467122
Exploratory Clinical Study of TCR-T for MAGE-A4-positive Mesenchymal Malignancies
Advanced Mesenchymal Malignancies
Идёт набор NCT07467863
Dual-Target CAR-NK Cells Directed Against MSLN, EGFR, or HER2 in Advanced NSCLC
Non-Small Cell Lung Cancer · Advanced/Metastatic NSCLC
Идёт набор NCT06623630
Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function
Multiple Myeloma
Набор скоро начнётся NCT07465198
Autologous Stem Cell Therapy in Patients With Multiple System Atrophy
MSA - Multiple System Atrophy · MSA
Идёт набор NCT04296487
Introduction of ACI for Cartilage Repair
Articular Cartilage Defect · Chondral Defect · Osteochondritis
Идёт набор NCT05535855
UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1
Acute Lymphoid Leukemia · Acute Lymphoblastic Leukemia
Идёт набор NCT06316856
CD5 Chimeric Antigen Receptor (CAR) T Cells in Subjects With Relapsed or Refractory T-cell Malignancies
T-Cell Acute Lymphocytic Leukemia · Acute Lymphoblastic Leukemia, in Relapse · Refractory Acute Lymphoblastic Leukemia
Набор скоро начнётся NCT07214974
Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
Mild Cognitive Impairment (MCI) · Early Stages of Cognitive Decline · Alzheimer's Disease Dementia
Идёт набор NCT06585514
Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE) · Lupus Nephritis (LN)
Набор скоро начнётся NCT07326059
Safety and Outcomes of MUSE Stem Cell Therapy in Individuals With Traumatic Brain Injury
Traumatic Brain Injury · Traumatic Brain Injury (TBI) Patients · Traumatic Brain Injury (TBI); Concussion, Initial Encounter
Идёт набор NCT06688799
Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases
Autoimmune Diseases
Идёт набор NCT07462650
Dual-Target CAR-NK Cells for Biomarker-Selected Advanced Colorectal Cancer
Colorectal Cancer Metastatic · Adenocarcinoma of Colon
Идёт набор NCT06326008
Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial
B-cell Acute Lymphoblastic Leukemia · Acute Lymphoblastic Leukemia, in Relapse
Набор скоро начнётся NCT07458659
Clinical Study of BCMA-Targeted CAR T-Cell Injection in the Treatment of Patients With Relapsed/Refractory Multiple Myeloma
Relapsed/Refractory Multiple Myeloma (MM)
Набор скоро начнётся NCT07454122
CD5CAR-NK Cells for Refractory Invasive Mold Disease
Fungal Infection
Набор скоро начнётся NCT07455500
Study of an Innovative Therapy Using CAR-T Cells Targeting IL-1RAP in Patients With High-Risk Myelodysplastic Syndromes (MDS
Myelodysplastic Syndrome
Идёт набор NCT06548607
Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases
SLE (Systemic Lupus) · Systemic Sclerosis · ANCA Associated Vasculitis
Набор скоро начнётся NCT07451236
CD19-BCMA Dual Nanobody Based CAR-T Cells for Patients With DSA
Transplantation Candidates With Hematological Diseases
Идёт набор NCT05672147
CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia
Acute Myeloid Leukemia · Recurrent Adult Acute Myeloid Leukemia · Refractory Acute Myeloid Leukemia
Идёт набор NCT05801913
Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin Lymphoma
High Grade B-Cell Non-Hodgkin's Lymphoma · Intermediate Grade B-Cell Non-Hodgkin's Lymphoma · Recurrent B-Cell Non-Hodgkin Lymphoma
Идёт набор NCT06880380
The Efficacy and Safety Study of CAR-T Cells for Functional Cure in HIV-1/AIDS Patients
HIV Infected Individuals · HIV
Идёт набор NCT07042438
Fecal Microbiome Transplant to Remodel Intestinal Microbiota for Patients With Relapsed or Refractory Lymphoma With Exposure to High-Risk Antibiotics Who Are Receiving Chimeric Antigen Receptor T Cells
Recurrent Diffuse Large B-Cell Lymphoma · Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements · Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Идёт набор NCT04510051
CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children
Malignant Brain Neoplasm · Recurrent Malignant Brain Neoplasm · Refractory Malignant Brain Neoplasm
Идёт набор NCT05934448
Pembro Plus CAR T-cell Therapy in R/R in PMBCL
Primary Mediastinal Large B-cell Lymphoma (PMBCL) · Primary Mediastinal Large B Cell Lymphoma · Primary Mediastinal Large B-Cell Lymphoma Refractory
Идёт набор NCT04328298
French Register Of Patients With Hemopathy Eligible For CAR-T Cell Treatment (DESCAR-T)
Hematopathology Eligible or CAR-t Cell Treatment
Набор скоро начнётся NCT06251544
TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer
Breast Cancer · Tumor, Breast · Breast Tumor
Идёт набор NCT04592640
Human Amniotic-Derived Mesenchymal Stem Cell Therapy for Calciphylaxis
Chronic Kidney Diseases · Calciphylaxis · Calcific Uremic Arteriolopathy
Идёт набор NCT06066346
A Study of Talquetamab for People With Multiple Myeloma Who Have Received BCMA CAR T-Cell Therapy
Multiple Myeloma
Идёт набор NCT03391778
Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
Neoplasms
Набор скоро начнётся NCT07447726
Exploratory Clinical Study on the Safety and Efficacy of CD19X CAR-T Cell Injection in the Treatment of Relapsed/Refractory Large B-Cell Lymphoma
Large B-Cell Lymphoma (LBCL)
Набор скоро начнётся NCT07447713
Reference Range Study for the Quantra System With the QPlus Cartridge in Pediatric Patients
Pediatric · Coagulation
Идёт набор NCT05306080
Tadekinig Alfa (IL-18BP) Rescue Therapy for CAR T Cell Related Cytokine Release Syndrome (CRS) and HLH-like Syndrome
CRS - Cytokine Release Syndrome · HLH
Идёт набор NCT07444281
An Phase I Trial of a CAR T-cell Infusion C-CAR031 in Participants With GPC3+ Advanced/Metastatic Squamous Cell Lung Cancer
Squamous Cell Lung Cancer
Идёт набор NCT06947473
Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.
Refractory Lupus Nephritis · Systemic Sclerosis · Primary Sjogren's Syndrome Combined With Pulmonary Hypertension
Идёт набор NCT06173518
A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)
Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia · Relapsed or Refractory B Cell Non-Hodgkin Lymphoma
Идёт набор NCT07444307
A Clinical Study of Dual-Target, Universal CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE)
Идёт набор NCT07169500
Clinical Study on the Safety and Efficacy of BCMA-CART±ASCT in Treating Young Multiple Myeloma Patients
Multiple Myeloma
Идёт набор NCT07441525
UCAR-T Targeting CD19/BCMA in Subjects With Autoantibody-Mediated Autoimmune Benign Hematological Diseases
Autoimmune Hemolytic Anemia · Primary Immune Thrombocytopenic Purpura · Evans Syndrome
Набор скоро начнётся NCT07438392
Tecar Therapy in Chronic Knee Osteoarthritis
Osteearthritis
Идёт набор NCT06612645
Safety and Efficacy of CMD03 CAR T Cell in Children With Relapse or Refractory Solid Tumors
Pediatric Cancers · Solid Tumor Pediatric
Идёт набор NCT06481241
Efficacy and Safety of Chemotherapy Combined With CAR-T Cells in Newly Diagnosed Adult Patients With Ph- B-ALL
Philadelphia Chromosome Negative ALL · Acute Lymphoblastic Leukemia, Adult
Идёт набор NCT07236801
Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune Diseases
Systemic Lupus Erythematosus (SLE) · Systemic Sclerosis · Sjogren's Syndrome (SS)
Идёт набор NCT06481228
Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL
Philadelphia Positive Acute Lymphoblastic Leukemia · Acute Lymphoblastic Leukemia, Adult
Идёт набор NCT07078929
Clinical Trial of CMD63 Chimeric Antigen Receptor T-cell (CAR T-cell) in Children With Acute Lymphoblastic Leukemia (ALL)
Relapse B Acute Lymphoblastic Leukemia · Refactory Childhood Acute Lymphoblastic Leukemia
Идёт набор NCT06474676
T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.
Metastatic Soft-tissue Sarcoma
Идёт набор NCT07435779
Autologous CAR-T Cell Therapy for Refractory and Relapsing Ulcerative Colitis: A Single-Center Exploratory Study
UC
Идёт набор NCT03552705
The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients
Anterior Cruciate Ligament Reconstruction
Идёт набор NCT06138132
A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis
Multiple Sclerosis · Multiple Sclerosis, Primary Progressive · Multiple Sclerosis, Secondary Progressive
Идёт набор NCT06209619
CC-99282 + Rituximab Early Post CART for Non-Hodgkin's Lymphoma
B-Cell Non-Hodgkin Lymphoma-Recurrent · Diffuse Large B-Cell Lymphoma-Recurrent · Follicular Lymphoma-Recurrent
Идёт набор NCT07049055
A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer
Pancreatic Cancer, Metastatic · PDAC - Pancreatic Ductal Adenocarcinoma
Идёт набор NCT07441291
CD19 CAR-T vs DLI for Post-HSCT MRD in Ph- ALL: A RCT
B ALL · Allogenetic Hematopoietic Stem Cell Transplantation · MRD-positive
Идёт набор NCT04536103
Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry
Bone Diseases, Infectious · Musculoskeletal Diseases · Joint Diseases
Идёт набор NCT07369492
Safety and Efficacy Study of BAFF-R CAR-T Cells in Adult Subjects With CD19-Negative Relapsed or Refractory B-Cell Lymphoma
B-cell Lymphoma
Набор скоро начнётся NCT06632301
DEXA Bone Density Analysis of the CoreHip® Prosthesis System
Primary Osteoarthritis · Cartilage Degeneration · Osteoarthritis, Hip
Набор скоро начнётся NCT07432100
Clinical Study on the Safety, Efficacy and Pharmacokinetics of Universal CLL1 Chimeric Antigen Receptor T-Cell in Relapsed/Refractory Acute Myeloid Leukemia
Acute Myeloid Leukemia · Chimeric Antigen Receptor T-cell · Universal CLL1 CAR-T
Идёт набор NCT06626919
A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases
Muscular Diseases · Neuromuscular Manifestations · Autoimmune
Идёт набор NCT07246096
Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases
Autoimmune Diseases · Systemic Lupus Erythematosus · Systemic Sclerosis
Идёт набор NCT06389305
CIK Cell Therapy for Relapsed or Refractory Acute B-Lymphoblastic Leukemia: Prognostic Impact on Patients With Early CAR-T Cell Dysfunction
B-cell Acute Lymphoblastic Leukemia · Acute Lymphoblastic Leukemia, in Relapse · Refractory Acute Lymphoid Leukemia
Идёт набор NCT07425483
CAR-NK Cells (CL-NK-003) in Pancreatic Cancer
Pancreatic Cancer
Идёт набор NCT06610344
BHB & CAR-T for Lymphomas
Large B-cell Lymphoma
Набор скоро начнётся NCT07427628
A Proof-of-concept Trial to EvaluAte the efficaCy and Safety Of Cell Therapy TRX103 in Patients With Active, Non-infectious Uveitis
Non Infectious Uveitis
Идёт набор NCT05432635
Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma
B-Cell Non-Hodgkin Lymphoma · Diffuse Large B-Cell Lymphoma · Mantle Cell Lymphoma
Идёт набор NCT06252402
CMV-specific HIV-CAR T Cells as Immunotherapy for HIV/AIDS
HIV-1
Набор скоро начнётся NCT07423572
Clinical Study of Anti-CD19/BCMA Universal Chimeric Antigen Receptor T Cells (UCAR-T) in the Treatment of Refractory Idiopathic Membranous Nephropathy (IMN)
Refractory Idiopathic Membranous Nephropathy
Идёт набор NCT03425526
Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease
Hematopoietic and Lymphoid Cell Neoplasm · Immunocompromised
Набор скоро начнётся NCT07417852
Effect of Cartoon Projection and Ball Squeezing on Pain During Venipuncture in Children
Venipuncture Pain
Идёт набор NCT07410494
Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors
Cancer · Breast Cancer · Non-Small Cell Lung Cancer (NSCLC)
Идёт набор NCT07416240
Exploratory Clinical Study of Claudin18.2-Targeted Activated DC and CAR-T Therapy in Advanced Pancreatic Cancer.
Advanced Pancreatic Cancer
Идёт набор NCT07174427
Multi-center Study of TBI-1301 (INN: Mipetresgene Autoleucel; Mip-cel) in Patients With NY-ESO-1 Positive Synovial Sarcoma
Synovial Sarcomas
Идёт набор NCT07342179
CAR-T Immunomonitoring in Multiple Myeloma (CART I5M)
Multiple Myeloma (MM)
Набор скоро начнётся NCT07412405
This Clinical Trial is a Single-arm, Non-randomized Pilot Trial to Determine the Safety of Administering Autologous Anti-C19 Cells (ARI-0001) and the Feasibility of Local CAR-T Cell Production in Patients Over 18 Years of Age With Relapsed/Refractory (R/R) CD19+ Hematologic Malignancies, Including R
Adult B-cell Acute Lymphoblastic Leukemia · Follicular Lymphoma (FL) · Mantle Cell Lymphoma (MCL)
Идёт набор NCT06823089
Early Feasibility Study of Cartilage Defect Repair
Osteoarthritis, Hip · Femoroacetabular Impingement · Osteonecrosis