Набор скоро начнётся NCT07616271
Study on the Effect of Oral Diammonium Glycyrrhizinate in Attenuating Toxicity and Enhancing Efficacy of CAR-T Cell Therapy
Patients With Large B-cell Lymphoma Receiving CAR-T Cell Therapy
CAR-T и клеточная терапия
1 352 исследования в этом разделе
Идёт набор NCT05858684
Dual Target CAR-T Cell Treatment for Refractory Systemic Lupus Erythematosus (SLE) Patients
CAR-T Cell Therapy
Идёт набор NCT04422912
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)
Pemphigus Vulgaris
Идёт набор NCT06788964
Loncastuximab Tesirine and Rituximab as Bridging Therapy Before Standard-of-care CAR-T Therapy in Patients With Large B-cell Lymphoma (CORAL)
Relapsed or Refractory Large B-cell Lymphoma
Набор скоро начнётся NCT07613788
Rimegepant Plus Glofitamab and CD19 CAR-T Therapy in R/R LBCL
Relapsed/Refractory Large B-cell Lymphoma (LBCL)
Идёт набор NCT05418088
Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies
Recurrent Acute Lymphoblastic Leukemia · Recurrent B Acute Lymphoblastic Leukemia · Recurrent B-Cell Prolymphocytic Leukemia
Набор скоро начнётся NCT07511426
U96-CAR-T-Cells For R/R B-ALL
Relapsed or Refractory B Cell Leukemia and Lymphoma
Идёт набор NCT06297226
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
Multiple Myeloma
Идёт набор NCT05826535
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Relapsed Non-Hodgkin Lymphoma · Refractory Non-Hodgkin Lymphoma · Non-Hodgkin Lymphoma
Набор скоро начнётся NCT07611149
Study to Evaluate the Safety of UF-KURE-BCMA CAR T-Cells in Advanced Myeloma
Multiple Myeloma in Relapse · Multiple Myeloma, Refractory
Идёт набор NCT07609485
Identifying Cellular and Molecular Determinants of Efficacy and Resistance in Patients Undergoing CAR-T Therapy
Cancer · Hematologic Malignancy
Идёт набор NCT06458439
Epcoritamab-CAR T Cells for Large B-cell Lymphomas
Lymphoma, Non-Hodgkin · Relapsed Diffuse Large B Cell Lymphoma · Refractory Diffuse Large B-cell Lymphoma
Идёт набор NCT07541391
Autologous Chimeric Antigen Receptor (CAR) T-cells Targeting the Kappa Myeloma Antigen (KMA) in Kappa Restricted Multiple Myeloma Patients With Relapsed/Refractory Disease
Relapsed/Refractory Multiple Myeloma
Идёт набор NCT05353530
IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma
Glioblastoma Multiforme · Glioblastoma
Идёт набор NCT07179380
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Pulmonary Hypertension · Interstitial Lung Disease
Идёт набор NCT07048197
A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease
Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)
Идёт набор NCT07343934
huCART19-IL18-eDHFR Cells in Relapsed/Refractory Follicular Lymphoma
Relapsed or Refractory Follicular Lymphoma
Идёт набор NCT06937567
CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors
Biliary Tract Cancer · Colorectal Carcinoma · Gastric Cancer, Metastatic
Идёт набор NCT04889716
CAR-T Followed by Bispecific Antibodies
Large B-cell Lymphoma · DLBCL - Diffuse Large B Cell Lymphoma
Идёт набор NCT05480449
Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)
B Cell Acute Lymphoblastic Leukemia (B-ALL) · B Lineage Lymphoblastic Lymphoma
Набор скоро начнётся NCT07234032
An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Pulmonary Hypertension · Interstitial Lung Disease
Идёт набор NCT04881240
Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia
Acute Lymphoblastic Leukemia, in Relapse · Acute Lymphoblastic Leukemia, Refractory · Pediatric ALL
Набор скоро начнётся NCT07605364
Testing the Addition of an Anti-Cancer Drug, Mycophenolate Mofetil, to the Usual Treatment (Radiation Therapy and Temozolomide) for Advanced Brain Cancer
Advanced Glioblastoma
Идёт набор NCT02443831
CARPALL: Immunotherapy With CD19+CD22 CAR T-cells for CD19+ and CD22+ Acute Lymphoblastic Leukaemia
Acute Lymphoblastic Leukemia
Набор скоро начнётся NCT07602322
LME-Guided Precision Combination Therapy in B-cell Lymphoma Patients After CD19 CAR-T Failure
Large B-cell Lymphoma
Идёт набор NCT07172958
Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)
Rhabdomyosarcoma · Ewing Sarcoma · Neuroblastoma
Идёт набор NCT06326021
Optimised CD33 (FL-33) CAR T Therapy for Refractory/Relapsed Acute Myeloid Leukaemia
Refractory/Relapsed Acute Myeloid Leukaemia
Идёт набор NCT07593820
A Phase I Interventional Open-label, Non-randomized Dose-escalation Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity, and Preliminary Anti-tumor Activity of Autologous p95HER2.CAR-TECH2Me T Cells in Patients With Selected Advanced Cancers.
Metastatic Gastric Cancer · Metastatic Breast Cancer · Endometrial Cancer Metastatic
Набор скоро начнётся NCT07596953
Efficacy of TECAR Therapy on Patient With Mechanical Neck Pain
MECHANICAL BACK PAIN
Набор по приглашению NCT07240857
A Clinical Study Evaluating the Safety and Efficacy of Local Injection of ACT#001 Chimeric Antigen Receptor T Cells in the Treatment of Castration-Resistant Prostate Cancer
Castration-Resistant Prostate Cancer (CRPC)
Идёт набор NCT06056102
CAR-T Cell Therapy for Desensitization in Kidney Transplantation
Kidney Transplant · Kidney Failure · End Stage Renal Failure on Dialysis
Идёт набор NCT06973668
A Randomized Study to Compare Post-transplant Cyclophosphamide, Sirolimus, Ruxolitinib and Post-transplant Cyclophosphamide, Sirolimus, Mycophenolate Mofetil to Prevent Graft Versus Host Disease
AML
Идёт набор NCT06615050
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)
Graft-versus-host Disease (GVHD)
Набор скоро начнётся NCT05976555
Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma
Multiple Myeloma
Идёт набор NCT06868290
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA
ANCA Associated Vasculitis (AAV)
Набор скоро начнётся NCT07599150
Intracranial CArtography of Cortical Contribution to Respiratory Load Compensation in Epilepsy
Epilepsy · SUDEP
Идёт набор NCT07598955
Target-Selected CAR-NK Cells (CD30, CD5, or Mesothelin) for Relapsed/Refractory B2 Thymoma or Thymic Carcinoma
B2 Thymoma · Thymic Carcinoma
Набор скоро начнётся NCT07575893
CD30 CAR-T Cells for Low Risk Relapsed Classical Hodgkin Lymphoma
Classical Hodgkin Lymphoma
Идёт набор NCT04318678
CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)
AML/MDS · B-ALL · T-ALL
Идёт набор NCT07428993
Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma
Pediatric Osteosarcoma
Идёт набор NCT06305299
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells
Ovary Neoplasm · Ovarian Cancer · Epithelial Ovarian Cancer
Идёт набор NCT06777979
CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia · Recurrent Acute Lymphoblastic Leukemia · Recurrent B Acute Lymphoblastic Leukemia
Идёт набор NCT04897321
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
Pediatric Solid Tumor · Osteosarcoma · Rhabdomyosarcoma
Идёт набор NCT07220993
Novel Unedited Allo Cell Therapy For High Risk T-Cell Malignancies Using CD7-Specific Car T Cells
T-cell Acute Lymphoblastic Lymphoma · T-non-Hodgkin Lymphoma · T-cell Acute Lymphoblastic Leukemia
Набор скоро начнётся NCT07572253
A Study of Using CARTO SOUND™ FAM to Guide Pulsed Field Ablation for Atrial Fibrillation
Atrial Fibrillation
Идёт набор NCT03326921
HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant
Juvenile Myelomonocytic Leukemia · Recurrent Acute Biphenotypic Leukemia · Recurrent Acute Undifferentiated Leukemia
Набор скоро начнётся NCT07593482
Bendamustine Versus Fludarabine/Cyclophosphamide for Lymphodepletion in Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T): a Randomized Trial.
B-cell Lymphoma
Набор по приглашению NCT07594496
Prevalence and Clinical Manifestations of Cannabis Withdrawal in Hospitalized Patients With Hematological Malignancies Undergoing Bone Marrow Transplant (BMT) or Chimeric Antigen Receptor T-Cell (CAR-T) Therapy
Hematopoietic and Lymphatic System Neoplasm · Malignant Solid Neoplasm
Идёт набор NCT07589517
Dual-Targeting CAR-NK Cells in Biomarker-Selected Advanced Colorectal Cancer
Colorectal Cancer · Metastatic Colorectal Adenocarcinoma · Unresectable Colorectal Cancer
Идёт набор NCT07589530
Phase 1/2 Study of EB-NK-301 (Allogeneic TROP2-CAR NK Cells) in Advanced TROP2-Expressing Solid Tumors
Advanced Solid Tumors · Metastatic Solid Tumors · TROP2-Expressing Solid Tumors
Идёт набор NCT07589543
Dual-Target CAR-NK Cells in Recurrent or Refractory Epithelial Ovarian Cancer
Epithelial Ovarian Cancer · Epithelial Ovarian Cancer, Fallopian Tube or Peritoneum
Идёт набор NCT01488240
The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars
Burn Scar
Идёт набор NCT07586267
CD19/BCMA UCAR-T for B Cell-Related Autoimmune Disease
Autoimmune Diseases · Systemic Lupus Erthematosus (SLE) · Multi-Drug Resistant Nephrotic Syndrome
Идёт набор NCT07493044
An Open-Label, Phase I Clinical Trial of Super CAR-T With GPC3-Positive Advanced Hepatocellular Carcinoma
Advanced Hepatocellular Carcinoma (HCC) · GPC3 Positive Hepatocellular Carcinoma
Идёт набор NCT07002112
The CD19/CD20 Dual-Target in Vivo CAR-T Lentiviral Product in the Treatment of Relapsed/Refractory B-cell Malignancies
Relapsed/Refractory B-cell Malignancies
Набор скоро начнётся NCT07586709
In Vivo BCMA/GPRC5D Tandem Dual CAR-T Therapy for Relapsed/Refractory Plasma Cell Neoplasms
Plasma Cell Neoplasms
Идёт набор NCT07587840
CD19/CD22 CAR-T as First-line Consolidation in Follicular Lymphoma
Lymphoma
Идёт набор NCT01619917
The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars
Burn Scar
Набор скоро начнётся NCT07584603
Effect of High-Intensity Laser Therapy on Femoral Cartilage in Knee Osteoarthritis
Osteoarthritis (OA) of the Knee · Osteoarthitis
Идёт набор NCT07395479
A Platform Study of In Vivo CAR-T for Treating Advanced Malignant Tumors Based on Target Screening
Advanced Malignant Tumours
Идёт набор NCT07259070
Multicenter, Single-Arm Exploratory Phase I Clinical Study (Assessment of Safety and Efficacy) of Fully Human BAFF-R Chimeric Antigen Receptor T-Cell Injection in Relapsed/Refractory BAFF-R-Positive B-Cell Lymphoma
DLBCL · CLL · FL
Идёт набор NCT07538635
CAR-T Combined With ASCT in the Treatment of Relapsed/Refractory Large B-cell Lymphoma With High-risk Factors.
High-risk R/R LBCL
Идёт набор NCT07052305
NT-I7 (Efineptakin Alfa), a Long-acting Human IL-7, Post-Axicabtagene Ciloleucel or Post-Lisocabtagene Maraleucel in Subjects With Relapsed/Refractory Large B-cell Lymphoma
Large B-cell Lymphoma
Идёт набор NCT07337785
CD19/BCMA-Targeted UCAR-T for Patients With Neurological Autoimmune Diseases
Relapsing or Refractory Multiple Sclerosis (MS) · Myasthenia Gravis (MG) · Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Набор скоро начнётся NCT07579208
A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma
Phase 1 · NK Cell · IL13Ra
Набор скоро начнётся NCT07567378
CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry
Psoriatic Arthritis · Osteoarthitis · Knee
Идёт набор NCT06532851
The Effect of Therapeutic Exercise on Cartilage Morphology and Physical Function for Individuals at High Risk of Knee Osteoarthritis
Meniscus Tear
Идёт набор NCT07178431
MB-CART2019.1 in Refractory Multiple Sclerosis
Multiple Sclerosis · CAR T Cell Therapy
Набор скоро начнётся NCT07577986
A Safety and Efficacy Trial of Chidamide Combined With NKG2D CAR-NK Cell Therapy for Reducing the HIV Viral Reservoir
HIV (Human Immunodeficiency Virus)
Идёт набор NCT07209241
Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM
Recurrent Glioblastoma
Идёт набор NCT06481735
TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALL
Acute Lymphocytic Leukemia
Идёт набор NCT07377435
DC/MM Fusion Vaccine With BCMA CAR-T in R/R MM
Multiple Myeloma · Refractory Multiple Myeloma · Relapse Multiple Myeloma
Набор скоро начнётся NCT05559801
Mesenchymal Cell Therapy in Osteogenesis Imperfecta (OI)
Osteogenesis Imperfecta · Osteogenesis Imperfecta Type III
Идёт набор NCT06964737
Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas
Recurrent Malignant Glioma · Recurrent WHO Grade 3 Glioma · Recurrent WHO Grade 4 Glioma
Идёт набор NCT06768905
IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL
Non Hodgkin Lymphoma · Diffuse Large B Cell Lymphoma
Идёт набор NCT05887167
Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies
Hematologic Malignancy · Large B-cell Lymphoma · Acute Lymphoblastic Leukemia
Идёт набор NCT06874946
Nanobody-Based Anti-CD5 CAR-T for Relapsed/Refractory T-ALL/NHL
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma · T - Cell Lymphoma · PTCL
Идёт набор NCT06500819
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors
Neuroblastoma · Sarcoma · Osteosarcoma
Набор скоро начнётся NCT07569263
IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With Brain Metastases
Brain Metastases
Набор скоро начнётся NCT06326203
Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb Ischemia
Peripheral Arterial Disease · Leg Ulcer
Идёт набор NCT07085676
Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases
Systemic Sclerosis (SSc) · Idiopathic Inflammatory Myopathy (IIM) · Rheumatoid Arthritis (RA)
Идёт набор NCT07093073
Clinical Study of U01（ssCART-19） in Patients With B-Cell Lymphoma
B Cell Lymphoma
Идёт набор NCT06043323
A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma
Follicular Lymphoma
Идёт набор NCT06784726
Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T
Recurrent Diffuse Large B-Cell Lymphoma · Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified · Recurrent Grade 3b Follicular Lymphoma
Идёт набор NCT07374029
Adoptive T Cell Therapy With DC/AML Fusion Vaccine Plus Decitabine and Venetoclax in AML
Acute Myeloid Leukemia · Acute Myeloid Leukemia, in Relapse
Идёт набор NCT06508931
Safety and Efficacy Study of Zamtocabtagene Autoleucel (MB-CART2019.1) in Pediatric Patients With R/R B-Cell Neoplasms
B-Cell Neoplasm
Идёт набор NCT07053059
Phase 2 Study Assessing the Clinical Activity and Safety of Obecabtagene Autoleucel as a Consolidation in Patients With Newly Diagnosed High-risk B-cell Acute Lymphocytic Leukemia (ALL)
Acute Lymphocytic Leukemia (ALL)
Идёт набор NCT07564219
BEAM-MM - β-Hydroxybutyrate-Enhanced Adaptive Immunity in Multiple Myeloma
Multiple Myeloma (MM) · CAR T Cells · Bispecific Antibodies
Идёт набор NCT07094100
Tissue Engineered Cartilage to Repairing Articular Cartilage Defects
Cartilage Injury · OA Knee
Идёт набор NCT05621668
A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma
Soft Tissue Sarcoma · Bone Sarcoma
Идёт набор NCT07361224
Investigator Initiated Study to Assess the Safety of Combination of CLS-015 With Anti-CD-19 CAR-T Cells in Patients With Stable/Progressive Large B Cell Lymphoma at Lymphodepletion.
Large B-Cell Lymphoma (LBCL)
Набор скоро начнётся NCT07562360
The Effectiveness of Tecar Therapy in Management of Calf Muscle Strain Injuries
Muscle Strain
Набор скоро начнётся NCT07009899
BCMA Bispecific Antibody Therapy for Post-BCMA CAR T-Cell Therapy Relapse (RECLAIM)
Multiple Myeloma
Идёт набор NCT05366569
Bio-CAR-T BS Study
Diffuse Large B Cell Lymphoma (DLBCL) · Primary Mediastinal Large B-cell Lymphoma (PMBCL) · Acute Lymphoblastic Leukemia (ALL)
Идёт набор NCT06696846
CD70-CAR-NK Cell Therapy for T Cell Lymphoma and Acute Myeloid Leukemia
Relapsed/Refractory T-cell Lymphoma · Relapsed/Refractory Acute Myeloid Leukemia
Идёт набор NCT07558850
Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune Diseases
Rheumatoid Arthritis · Dermatomyositis · Systemic Lupus Erythematosus
Идёт набор NCT07465549
CART BP Pro-Guided Blood Pressure Management for Uncontrolled Hypertension
Hypertension
Набор скоро начнётся NCT07546630
Nanobody-Based CD19/CD20 Tandem Dual CAR-T-cell Therapy of Relapsed/Refractory B-Cell Lymphoma
Relapsed/Refractory B-Cell Lymphoma
Идёт набор NCT07048535
CAR T-cell Long-Term Follow-Up, Quality of Life and Adverse Reactions
B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Идёт набор NCT07072234
Phase I Study of Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells in Treatment Refractory Clear Cell Renal Cell Carcinoma
Clear Cell Carcinoma · Phase 1 · Growth Factor